The European Stroke Organisation (ESO) Executive Committee’s Thrombolysis Taskforce has provided “important updates” regarding the security of supply for Metalyse (tenecteplase) and Actilyse (alteplase) in the context of the European launch of Metalyse 25mg for acute ischaemic stroke treatment....
In a systematic review and meta-analysis of the current literature, deep brain stimulation (DBS) with a short pulse width has been shown to potentially induce more tremor reduction in essential tremor patients, but does not appear to offer a...
Siemens Healthineers and the World Stroke Organization (WSO) have announced a two-year partnership to develop the acute stroke workforce, and improve treatment and care for stroke. Stroke is the second-leading cause of death and the third-leading cause of disability in...
Zeto has announced that its innovative, next-generation brain monitoring product, named the ONE, has received 510(k) clearance from the US Food and Drug Administration (FDA). "Zeto ONE is a breakthrough EEG system, revolutionising many aspects of emergency EEG acquisition,” said...
Global conference coverage piqued NeuroNews readers’ interest through the month of May—initially with discussions at the Charing Cross (CX) International Symposium (23–25 April, London, UK) and, later, thanks to new trial data presented at this year’s European Stroke Organisation...

Adnan Siddiqui

While he is a neurosurgeon by trade, Adnan Siddiqui (Buffalo, USA) has delved into an increasing number of domains throughout his career—not only through his interest in endovascular treatments and the neurosciences, but also via significant involvement in clinical...
Nalu Medical has revealed findings from a landmark clinical trial evaluating its Nalu peripheral nerve stimulation (PNS) system, utilising the company’s proprietary micro-implantable pulse generator (micro-IPG) to treat chronic pain patients. Nalu’s COMFORT study is a post-market, multicentre randomised controlled...
In acknowledgement of their shared goals and interests, the European Society of Minimally Invasive Neurological Therapy (ESMINT) and the German Society of Neuroradiology (DGNR) announced today that they have formalised a collaboration to define joint actions, achieve the best possible...
Earlier today, Sensome announced positive results from its first-in-human CLOT OUT clinical trial evaluating the safety and performance of the company’s Clotild smart guidewire system used during mechanical thrombectomy treatments for ischaemic stroke. The results showed that the technology...
Medtronic has today announced the European launch of Artisse—a new intrasaccular device designed to treat intracranial aneurysms by conforming to the shape of the aneurysm. The launch coincides with interim data that examine the safety, efficacy and performance of...
In what has been described as the first study of its kind, researchers from the Keck School of Medicine at the University of Southern California (USC) in Los Angeles, USA and the California Institute of Technology (Caltech) recently designed...
This advertorial, intended for readers outside the USA only, is sponsored by Medtronic. In light of the official European launch of the Artisse aneurysm embolisation system (Medtronic) at LINNC Paris 2024 (3–5 June, Paris, France), NeuroNews speaks to three of...
Following the recent publication in Stroke: Vascular and Interventional Neurology of results from HEMERA-1, a prospective, multicentre trial evaluating the safety of novel neuroprotective agent PP-007 (Prolong Pharmaceuticals) alongside mechanical thrombectomy in acute stroke patients, lead investigator Italo Linfante...
Intravenous thrombolysis (IVT) prior to a mechanical thrombectomy procedure appears to be less effective in ischaemic stroke patients with carotid-artery tandem lesions, as compared to in patients without tandem lesions, according to the findings of a MR CLEAN-NO IV...
Seven-year data from the Chinese CASSISS trial have, in the investigators’ view, provided “compelling evidence” that percutaneous transluminal angioplasty and stenting (PTAS) plus medical therapy does not confer additional benefits over medical therapy alone in patients with symptomatic, severe...
The use of a smartphone-based mobile application may be an effective method for improving medication adherence and risk-factor control among stroke survivors, and appears to be a feasible approach in low- and middle-income countries (LMICs). This is the salient...
This year’s European Stroke Organisation Conference (ESOC; 15–17 May, Basel, Switzerland) saw a plethora of data on intravenous tenecteplase—from studies spanning Australia, Canada, China, Europe, and beyond—presented for the first time. Fresh findings from the ATTENTION-IA, ORIGINAL, TASTE, TEMPO-2...
Ceretrieve has announced the successful results of the company's multicentre, single-arm study, showcasing the capabilities of its “state-of-the-art” aspiration catheter in stroke treatment. The study—conducted across two centres—included 20 patients suffering from acute ischaemic stroke due to intracranial large vessel occlusion (LVO)...
Medtronic has today announced that Linnea Burman will succeed Dan Volz as its senior vice president (SVP) and president of its Neurovascular business—part of the company’s Neuroscience portfolio. In her new capacity, Burman will be responsible for portfolio strategy, product...
New data from the C-GUARDIANS pivotal investigational device exemption (IDE) trial support consideration of carotid artery stenting (CAS) with the CGuard embolic prevention stent system (EPS; InspireMD) as a "frontline therapeutic option for appropriate patients being considered for carotid...
Spryte Medical has announced the publication of a first-in-human study of its neuro optical coherence tomography (nOCT) technology in the peer-reviewed journal Science Translational Medicine, in a paper entitled, “Volumetric microscopy of cerebral arteries with a miniaturised optical coherence tomography imaging...
This advertorial, intended for US readers only, is sponsored by Q’Apel Medical. Hot on the heels of the device’s Food and Drug Administration (FDA) approval and subsequent US launch, Jan-Karl Burkhardt (Penn Medicine, Philadelphia, USA) and Omar Tanweer (Baylor College...
A number of somewhat conflicting studies have been published over the past year regarding triage and transport protocols for stroke. In light of the most recent of these publications, NeuroNews speaks to Ashutosh Jadhav (Barrow Neurological Institute, Phoenix, USA)...
AiM Medical Robotics has announced a collaboration with Brigham and Women's Hospital (BWH; Boston, USA), and the Surgical Navigation and Robotics (SNR) Lab at Harvard, to validate its cutting-edge robot for deep brain stimulation (DBS) in Parkinson's disease patients. AiM recently entered into a clinical...
Three papers published in the journal Stroke have highlighted multidisciplinary care and global, collaborative efforts as “paramount” in the management of intracranial aneurysms, chronic subdural haematomas (cSDHs), and brain arteriovenous malformations (AVMs). These recommendations were led by the Aneurysm/AVM/cSDH...
Vesalio is set to welcome J D McCulloch as its chief financial officer (CFO) for overseeing all financial aspects of the business, and helping drive the company’s financial strategy and business development. According to a press release, he will...
XCath has announced the successful completion of a “first-of-its-kind” live telerobotic trial for stroke treatment, which took place between Abu Dhabi, United Arab Emirates (UAE) and Seoul, South Korea at Abu Dhabi Global Healthcare Week (ADGHW; 13–15 May, Abu Dhabi, UAE). In...
Despite the study very narrowly failing to meet its prespecified primary endpoint, the SWITCH randomised controlled trial has shown a substantial treatment effect with decompressive craniectomy procedures in people with severe, deep supratentorial intracranial haemorrhage (ICH). These findings were...
Highlights: ARISE I recommendations on the management of intracranial aneurysms, chronic subdural haematomas (cSDHs) and brain arteriovenous malformations (AVMs) First European presentation of PERFORMANCE II trial data and subsequent discussions at the 2024 Charing Cross (CX) International Symposium (23–25...
Highlights: ARISE I recommendations on the management of intracranial aneurysms, chronic subdural haematomas (cSDHs) and brain arteriovenous malformations (AVMs) First European presentation of PERFORMANCE II trial data and subsequent discussions at the 2024 Charing Cross (CX) International Symposium (23–25...
MagVenture has announced a partnership with Magnus Medical that is intended to provide its industry-leading MagPro magnetic stimulation system to support an “exciting new chapter” in therapeutic transcranial magnetic stimulation (TMS) through Magnus' SAINT neuromodulation system. A company press release notes that...
While the randomised controlled SELECT2 trial initially found that patients with large-core ischaemic stroke receive a greater benefit from thrombectomy compared to medical management, a secondary analysis of data from the study has now shown that the benefits of...
The latest data from the INTERACT trials—a series of studies evaluating intensive blood-pressure (BP) lowering in acute haemorrhagic stroke—point towards the importance of initiating BP reduction as early as possible in patients with intracranial haemorrhage (ICH), but also highlight...
The TENSION trial, conducted across 41 hospitals in Europe and Canada, has unveiled new insights into the long-term efficacy of endovascular mechanical thrombectomy in patients suffering from acute ischaemic stroke caused by large infarcts. Götz Thomalla (University Medical Center...
Brainomix has announced that results from what it claims is the largest prospective study of stroke artificial intelligence (AI) software were presented yesterday at the European Stroke Organisation Conference (ESOC; 15–17 May, Basel, Switzerland), showing that the implementation of...
TACTICS, a non-randomised intervention trial that aimed to optimise workflow and implement specialised imaging, has shown promise in improving access to endovascular therapy (EVT) for patients in regional and rural areas of Australia. “While EVT has revolutionised stroke treatment, access...
Rapid Medical has announced what it claims is the first successful robotic thrombectomy, in Medellín, Colombia. Two patients were treated with the robotic Tigertriever—an endovascular thrombectomy device that adapts autonomously to the patient’s anatomy. “Automating stroke procedures is a significant...
New research, presented today at the 10th European Stroke Organisation Conference (ESOC 2024; 15–17 May, Basel, Switzerland), has revealed that high-income individuals have a 32% lower risk of post-stroke mortality. Additionally, those with a higher level of education have...
Cerevasc announced recently that it has successfully completed the initial closing of a US$70 million Series B financing, which was jointly led by Bain Capital Life Sciences and existing investor Perceptive Xontogeny Venture Fund (PXV), with additional participation from other existing...
Hyperfine has announced that it has entered into agreements with three experienced and accomplished distributors to support commercial expansion plans of the Swoop system—the “first” US Food and Drug Administration (FDA)-cleared portable magnetic resonance (MR) brain imaging system—into European...
An international, multicentre study has confirmed the existence of the carryover or ‘echo’ effect—an interval before patients perceive the return of pain after their spinal cord stimulation (SCS) system has been deactivated—and also indicated a “remarkably high” degree of...
NeuroNews’ top 10 most popular stories of April 2024 include the European launch of a new aspiration catheter for acute ischaemic stroke treatment, a study evaluating transradial versus transfemoral access approaches in mechanical thrombectomy, and the long-awaited publication of...
RapidAI has announced that the US Food and Drug Administration (FDA) has granted 510(k) clearance for its AngioFlow by RapidAI solution. As per a company press release, this module delivers perfusion imaging analysis directly within the interventional suite to promote greater...
The recent, first-time European presentation of the PERFORMANCE II trial’s findings—delivered by Ralf Langhoff (Sankt Gertrauden-Krankenhaus, Berlin, Germany) at the 2024 Charing Cross (CX) International Symposium (23–25 April, London, UK)—led delegates to discuss the role of stenting in carotid...
Today, Penumbra announced the launch of its Midway 43 and Midway 62 delivery catheters, which are designed to provide ideal tracking and a stable platform to support the delivery of various embolisation therapies in the neurovasculature. This news came...
The latest product innovation by Nico Corporation, the Myriad Spectra system, has been described as a "game-changing advancement" by neurosurgeons with early experience using the device. That is according to a company press release, which also details that Myriad...
An initial evaluation of vagus nerve stimulation (VNS) in narcolepsy patients has linked this neuromodulation modality to a “significant improvement” in daytime sleepiness, leading researchers to aver that VNS could be a promising non-medical treatment option for this condition...
MindRhythm has announced that results from the pilot phase of its three-phase clinical study, EPISODE, have been published in Academic Emergency Medicine. While pilot EPISODE data have been presented in various academic society forums, this is the first official...
A study presented at the recent American Academy of Neurology (AAN) annual meeting (13–18 April, Denver, USA) has gone some way to elucidating how two factors—patient age, and connectivity of electrodes to the subiculum-retrosplenial cortex (SBC-RSC)—may impact the cognitive...
Route 92 Medical has today announced receipt of US Food and Drug Administration (FDA) 510(k) clearance for the FreeClimb 54 reperfusion system, comprised of the FreeClimb 54 aspiration catheter paired with a Tenzing 5 delivery catheter. This new system...
The European Society of Minimally Invasive Neurological Therapy (ESMINT) has issued a call for experts in neurointerventions to work with notified bodies over the certification process of medical devices within the European Union (EU). The society recently established a Medical...
Viz.ai has announced a collaboration with Nico Corporation to improve the lives of patients with intracranial haemorrhages (ICHs), leveraging the former’s artificial intelligence (AI)-powered disease detection and intelligent care coordination products, and the latter’s modern, minimally invasive interventional technologies...
Insightec has announced the CE-mark approval and European launch of Exablate Prime, which the company describes as a “significant enhancement” to its Exablate Neuro platform—a magnetic resonance imaging (MRI)-guided neurosurgery system that uses focused ultrasound to treat medication-refractory essential...
A retrospective analysis including data from close to 3,000 stroke patients has concluded that early changes in mechanical thrombectomy strategies may be associated with higher reperfusion rates and therefore “should be contemplated” following failed attempts with first-line standalone contact-aspiration...
Cerenovus, part of Johnson & Johnson MedTech, has today announced the launch of its Cereglide 71 aspiration catheter in Europe, an aspiration catheter equipped with TruCourse technology, indicated for the revascularisation of patients suffering from acute ischaemic stroke. The...
Cognito Therapeutics has announced treatment results from OVERTURE II—an open-label extension (OLE) study of Spectris, the company’s potential disease-modifying therapy for the treatment of Alzheimer’s disease. The results in question were presented at the 2024 American Academy of Neurology...
The past three decades have seen a “notable rise” in the burden of haemorrhagic stroke across the USA and this, coupled with the increasing burden of stroke more generally, represents an “evolving and substantial public health challenge” for the...
The entirety of the results from the ENRICH trial evaluating the early surgical removal of intracranial haemorrhage (ICH) have been published in the New England Journal of Medicine (NEJM). As stated in a Nico Corporation press release, ENRICH demonstrated early...
How is innovation in stroke care guided by contemporary clinical trials? This was the question NeuroNews put to Atul Gupta, the Chief Medical Officer of Diagnosis & Treatment at Philips, who discussed what he sees as the recent trials...
SpineX has closed recruitment for the CONTINENCE clinical trial of its proprietary Scone device. The study began back in May 2022 and is evaluating the company’s spinal cord stimulation (SCS) technology in the treatment of neurogenic bladder patients. Scone is...
Synchron has announced the launch of a community-centred brain-computer interface (BCI) registry to bring patients, carers and clinicians together to learn how BCI technology is being designed to provide benefit to people with limited mobility. Synchron’s BCI technology—primarily seen in...
Researchers have found that electroconvulsive therapy (ECT)—whereby an electric current is passed through the brain of a patient under general anaesthesia to induce a brief seizure—can reduce the severity of mental illnesses. A recent study, which was presented at the...
NOTE: This video is ONLY available to watch in selected countries and geographies Edgar Samaniego (University of Iowa, Iowa City, USA) discusses his experiences to date with one of the latest technologies in the mechanical thrombectomy space—the CEREGLIDE™ 71...
XCath has announced that it presented at the recent Stroke Live Course (SLICE) Next Frontiers conference (3–4 April, virtual), hosted by Vincent Costalat (University Hospital of Montpellier, Montpellier, France), and Master and Fellow. The event—broadcast live from the Montpellier Centre Hospitalier Universitaire...
Major pieces of industry news from a number of innovators in the neurovascular space populate NeuroNews’ top 10 articles of last month—including NeuroOne, Artiria, Arissa and Nanoflex Robotics. Data indicating the more long-term benefits of thrombectomy in patients with...
A study recently published online in the journal Interventional Neuroradiology has provided multicentre trial results that demonstrate the promise of using precise cyclic aspiration in the treatment of acute ischaemic stroke, as per a press release put out today by US...
Artificial intelligence (AI) may serve as a future tool for neurologists to help locate the part of the brain in which a stroke occurred, as per the findings of a new study. In the study, AI—more specifically, a large...
Silk Road Medical has announced the launch of its Enroute transcarotid neuroprotection system Plus (NPS Plus), which the company describes as a key component of its transcarotid artery revascularisation (TCAR) portfolio. As per a Silk Road press release, this next-generation device builds...
The programme for the 2024 Charing Cross (CX) symposium (23–25 April, London, UK) will see the topics of acute stroke care, carotid disease and neurointerventional surgery return with renewed vigour, thanks in no small part to five separate debate...
An analysis involving some 300 patients with anterior-circulation acute ischaemic strokes caused by tandem lesions has determined a number of factors that may be predictive of good clinical outcomes at three months following an endovascular mechanical thrombectomy procedure. Said...
This advertorial, intended for readers outside the USA only, is sponsored by Medtronic. In light of a recent publication detailing the safe and effective use of the Solitaire X 3mm (Medtronic) stent retriever in medium- and distal-vessel occlusion (MeVO/DVO) stroke,...
Data from a new study that maps out the levels at which adverse postoperative events decrease following transfemoral carotid artery stenting (TfCAS) based on depth of physician experience with the procedure represent an “absolute minimum threshold of learning”, according...
This advertorial is sponsored by Medtronic. Late last year, on 24 November, a decade’s work from a passionate group of physicians bore fruit, with the Brazilian Ministry of Health adding mechanical thrombectomy for stroke to the list of procedures covered...
Viz.ai has announced a strategic collaboration with Medtronic to improve the coordination of cryptogenic stroke patient care between neurology and cardiology teams. For stroke patients who are at risk of atrial fibrillation (AF) post-stroke and may need additional cardiac monitoring,...
Michihiro Tanaka

Michihiro Tanaka

Michihiro Tanaka, director of Neurosurgery and Neuroendovascular Surgery at Kameda Medical Center (Chiba, Japan), speaks to NeuroNews to discuss the factors that have shaped his career as a neurosurgeon, his tenure as World Federation of Interventional and Therapeutic Neuroradiology...
In stroke patients undergoing a mechanical thrombectomy procedure, access via the radial artery may be non-inferior to access through the femoral artery in terms of final recanalisation-related outcomes. However, reduced procedural delays associated with the latter mean transfemoral access...
Researchers have argued that “more needs to be done” for depressed stroke survivors in light of new findings showing that almost 60% of stroke survivors would experience depression within 18 years—a much higher estimation than previous studies, and one...
NeuroOne Medical Technologies has announced that it has initiated a limited commercial launch of its OneRF ablation system, which has US Food and Drug Administration (FDA) 510(k) clearance for creation of radiofrequency (RF) lesions in nervous tissue for functional neurosurgical...
After providing NeuroNews with an overview of the recent history of arteriovenous malformation (AVM) treatment in a previous video interview, Christophe Cognard (Toulouse University Hospital, Toulouse, France) summarises his own preferred approach to these cases, and takes a more...
Avicenna.AI announced today that it has received 510(k) clearance from the US Food and Drug Administration (FDA) for its CINA-ASPECTS and CINA-iPE products. CINA-ASPECTS is an artificial intelligence (AI) tool for stroke severity assessment, automatically processing non-contrast computed tomography (NCCT)...
Recently, NeuroNews caught up with Christophe Cognard (Toulouse University Hospital, Toulouse, France) to discuss the current landscape of arteriovenous malformation (AVM) care. Cognard outlines the growing evidence and ongoing research that appear to contrast with seminal findings from ARUBA—a...
Medtronic has announced that the Patent Trial and Appeal Board (PTAB) of the US Patent and Trademark Office has affirmed the validity of claims in two of its patents in an ongoing patent infringement lawsuit filed by Medtronic against...
A meta-analysis published recently in the Journal of the Neurological Sciences has concluded that venous sinus stenting (VSS) appears to be a safe and effective treatment option in certain idiopathic intracranial hypertension (IIH) patients—specifically, those who do not respond...
Highlights: The “major shift” likely to occur following presentation of three large-scale trials evaluating middle meningeal artery (MMA) embolisation for chronic subdural haematoma (SDH) Numerous other studies presented for the first time at this year’s International Stroke Conference (ISC;...
Highlights: The "major shift" likely to occur following presentation of three large-scale trials evaluating middle meningeal artery (MMA) embolisation for chronic subdural haematoma (SDH) Numerous other studies presented for the first time at this year's International Stroke Conference (ISC;...
Arissa Medical has announced six-month digital subtraction angiography (DSA) follow-up of the first cohort of patients in its Syntra first-in-human (FIH) study—an early feasibility study evaluating the safety and efficacy of the company’s Syntra device for the treatment of...
Mainstay Medical has announced the publication of the five-year follow-up from its ReActiv8-B randomised, sham-controlled, double-blinded trial in Neuromodulation: Technology at the Neural Interface. There were 126 patients who completed the five-year follow-up and—as per a Mainstay press release—the published...
Intracranial aneurysms are a largely underestimated condition, for which global awareness and clinical research are currently lacking—and these sentiments apply even more pertinently when it comes to hereditary brain aneurysms. For NeuroNews, Rebecca Middleton (Leicester, UK) discusses how her...
Hans-Henning Eckstein, the vascular surgeon who played a leading role in the SPACE and SPACE 2 randomised controlled trials on the treatment of carotid stenosis and founder of the Munich Vascular Conference (MAC), died on 24 February at the...
Axonics has announced that the Axonics R20 rechargeable sacral neuromodulation (SNM) system has received CE-mark approval. Axonics expects to commence sales of the R20 to European customers in mid-April, as per a company press release. The R20 also received approval...
A large, single-centre analysis has found that, despite parity between the two procedures in terms of perioperative clinical outcomes, carotid endarterectomy (CEA) was associated with a reduced rate of late stroke/death compared to transcarotid artery revascularisation (TCAR). Writing in...
Switzerland-based startup firm Nanoflex Robotics has announced that it recently installed its first remote-ready robotics system for neurovascular procedures at the Jacobs Institute (Buffalo, USA). The Nanoflex Robotics system uses a compact magnetic field generator and a navigation control unit...
Our list of the most popular stories from last month is dominated by first-time data releases from the International Stroke Conference (ISC; 7–9 February, Phoenix, USA), with the red-hot topic of liquid embolic use in subdural haematoma (SDH) patients...
Apollo Hospitals announced today that one of its centres in New Delhi, India has become the first hospital in South Asia to introduce the ZAP-X gyroscopic radiosurgery platform (Zap Surgical), describing the event as a “significant milestone”. The ZAP-X technology...
Nalu Medical has announced the closing of an incremental US$20 million in equity financing from new investor B Capital, bringing its total Series E round of equity investment to US$85 million. According to a press release, this funding will...
For ischaemic stroke patients, social factors like education, neighbourhood and employment may be linked to whether they receive treatment with intravenous, clot-busting drugs, according to a preliminary study that was released recently and is set to be presented at...
Medtronic recently announced that it has filed a complaint with the US International Trade Commission (ITC), along with a parallel action in US District Court for the District of Delaware, to block Axonics from “improperly importing and selling products”...
Silk Road Medical has announced the launch of its tapered Enroute transcarotid stent system to hospitals in the USA, expanding upon the company’s prior Enroute transcarotid stent system and offering additional configurations to better tailor the transcarotid artery revascularisation...
Artiria Medical has announced the successful closing of a Series A2 round worth US$6 million and the securing of a US$600,000 Fit Tech Growth loan. The Series A2 investment round, led by 4FOX Ventures, was joined by the Wyss...
This year’s International Stroke Conference (ISC; 7–9 February, Phoenix, USA) hosted discussions on the current state of play in carotid stenosis treatment—and, most notably, advances that may erode the dominance of long-established carotid revascularisation procedures in the USA. Session moderator...
Onward Medical announced recently that it has been awarded Breakthrough Device designation (BDD) by the US Food and Drug Administration (FDA) for the ARC-BCI system, which uses brain-computer interface (BCI) technology in conjunction with the company’s ARC-IM therapy to restore thought-driven...
In a guest article for NeuroNews, Adnan Mujanovic (Bern, Switzerland) discusses a relatively unknown but potentially significant factor in stroke patients experiencing poor clinical outcomes following a successful endovascular therapy (EVT) procedure—the ‘no-reflow’ phenomenon. EVT has revolutionised the treatment for...
Royal Philips has announced major enhancements to its image-guided therapy system—Azurion—with the launch of its new Azurion neuro biplane system. Featuring enhanced imaging and gantry positioning flexibility, this new angio suite system is designed to streamline neurovascular procedures and help...
One-year follow-up data from two randomised controlled trials (RCTs) evaluating mechanical thrombectomy in patients with ischaemic strokes caused by large-core infarct volumes have demonstrated the more long-term clinical benefits of the procedure—when coupled with standard medical management (MM). Both trials—TESLA...
A subgroup analysis of the ASTER2 clinical trial has found that a first-line combined thrombectomy approach, which involves using contact aspiration and a stent retriever in tandem, may produce better reperfusion outcomes compared to use of a stent retriever...
Tivic Health Systems has announced that enrolment in its pilot clinical study of a proprietary approach to non-invasive vagus nerve stimulation (VNS) has been completed. Tivic is testing a proprietary approach to more precisely influence vagus nerve signals, while enhancing...
The University of Cincinnati’s Center for Addiction Research and Spark Biomedical have jointly announced that they are conducting a clinical trial to help patients with opioid use disorder (OUD) and post-traumatic stress disorder (PTSD) stick with medication treatment while...
Route 92 Medical has today announced the completion of enrolment in the 250-patient SUMMIT MAX clinical trial evaluating the safety and effectiveness of its HiPoint 88 and HiPoint 70 reperfusion catheters as part of the Monopoint reperfusion system. Route...
Combining brain stimulation with intense physical rehabilitation helped stroke survivors recover movement in their arms and hands, and maintain these improvements for one year, within a study presented at the International Stroke Conference (ISC; 7–9 February, Phoenix, USA). “The recovery of arm...
NOTE: This video is ONLY available to watch in selected countries and geographies  Interventional neuroradiologists Vincent Costalat (University Hospital of Montpellier, Montpellier, France) and Marios Psychogios (University Hospital Basel, Basel, Switzerland) are currently focused on two very different matters...
Reteplase has demonstrated potential as an alternative to alteplase in patients requiring intravenous thrombolysis (IVT) to treat acute ischaemic stroke, as per the findings of the RAISE trial, which were presented by Yongjun Wang (Beijing Tiantan Hospital, Beijing, China)...
In an official statement, the Society of Neurolnterventional Surgery (SNIS) has acknowledged middle meningeal artery (MMA) embolisation as a beneficial adjunctive treatment for chronic subdural haematoma (SDH). This follows the presentation of new research at the recent International Stroke...
The use of middle meningeal artery (MMA) embolisation alongside standard care has been deemed superior to standard care alone for patients with symptomatic, non-acute subdural haematomas (SDHs), as per the findings of the MAGIC-MT randomised controlled trial (RCT). Ying...
Late-breaking findings from the TWIN2WIN trial—presented recently at the International Stroke Conference (ISC; 7–9 February, Phoenix, USA)—have demonstrated the potential benefits of performing mechanical thrombectomy procedures using two stent retrievers (SRs) simultaneously. The trial compared a first-line dual-SR strategy...
Viz.ai has announced receipt of US Food and Drug Administration (FDA) 510(k) clearance for its Viz Intracerebral Haemorrhage (ICH) Plus algorithm, which is intended to automate the process of identifying, labelling and quantifying the volume of segmentable brain structures...
RapidAI has announced the publication of TIMELESS—a randomised trial evaluating the use of tenecteplase in acute ischaemic stroke treatment—in the New England Journal of Medicine (NEJM), in addition to multiple other data from research studies unveiled at this year’s International...
Mainstay Medical has announced that the US Food and Drug Administration (FDA) has approved full-body magnetic resonance imaging (MRI) conditional labelling for the ReActiv8 restorative neurostimulation system—an implantable medical device designed to treat adults with intractable chronic low back...
Recently presented results from the STEM randomised controlled trial (RCT) have demonstrated improved outcomes with middle meningeal artery (MMA) embolisation plus standard management—as compared to standard management alone—in patients with chronic subdural haematoma (cSDH). At the 2024 International Stroke...
Laying large vessel occlusion (LVO) ischaemic stroke patients flat with their heads at a zero-degree angle prior to a mechanical thrombectomy procedure has resulted in significant short-term improvements in neurological function, as compared to patients whose heads were elevated...
Sensome has announced enrolment of the first patients into a feasibility clinical study using the Clotild smart guidewire in peripheral artery disease (PAD). Clotild was designated a breakthrough medical device for use in brain arteries by the US Food and...
Middle meningeal artery (MMA) embolisation—the injection of a liquid embolic substance to block an artery feeding the brain’s dura—along with surgery for subacute or chronic subdural haematoma (SDH) has been found to reduce the risk of patients requiring repeat...
Cerenovus, part of Johnson & Johnson MedTech, has announced the launch of its Cereglide 71 device—a next-generation intermediate catheter with TruCourse technology indicated for the revascularisation of patients suffering from acute ischaemic stroke. The device is now commercially available...
Ischaemic stroke survivors who received care recommendations from an artificial intelligence (AI)-based system experienced fewer recurrent strokes and heart attacks, and a lower rate of vascular death, within three months—as compared to people whose stroke treatment was not guided...
The use of a relatively novel scoring system, referred to as Symptomatic carotid atheroma inflammation lumen-stenosis (SCAIL), has produced favourable predictive qualities versus the Oxford carotid stenosis tool (OCST) and Essen stroke risk score (ESRS). According to researchers, the...
Giving blood thinners in addition to clot-busting medications does not improve ischaemic stroke patients’ outcomes at 90 days, according to findings from the MOST trial, which were revealed today in a late-breaking science presentation at the International Stroke Conference (ISC; 7–9...
A new scientific statement from the American Heart Association (AHA) emphasises the need to boost patient and physician awareness of cerebral venous thrombosis (CVT), with a view to improving recognition of this condition and initiation of prompt medical treatment....
Boston Scientific Corporation announced today that the US Food and Drug Administration (FDA) has approved an expanded indication of the company’s WaveWriter spinal cord stimulation (SCS) systems for the treatment of chronic low back and leg pain in people...
A new guidance document from the UK National Institute of Health and Care Excellence (NICE) has endorsed National Health Service (NHS) deployment of two artificial intelligence (AI)-derived software technologies to support the review and reporting of computed tomography (CT)...
Carthera has announced the enrolment of the first patient in the SONOBIRD pivotal trial assessing its ultrasound-based Sonocloud medical device for the treatment of recurrent glioblastoma (rGBM). The trial aims to treat 560 patients across 40 sites in Europe and the USA,...
Brian Nahed (Boston, USA) outlines the latest advances in neurosurgery, and why it is important for those working in the field to keep up to date and continually hone their skills, in a guest article on NeuroNews. Training and education...
Lumosa Therapeutics, in collaboration with CHI Memorial (Chattanooga, USA), has announced the initiation of multiple Phase 2 clinical trials for LT3001, which the company describes as a “groundbreaking” drug for treating acute stroke that combines clot-busting and nerve-protecting effects...
Endovascular brain-computer interface (BCI) technology firm Synchron has announced the acquisition of an equity stake in Acquandas—a leading technology provider specialising in state-of-the-art, high-precision components in healthcare and other industries. As part of the transaction, Synchron chief executive officer (CEO) and...
Irish medical device firm Ceroflo announced today that it has raised €6.4 million in investment-round funding, which will be used to advance development of the company’s SubMax device—a novel stent intended to “revolutionise” intracranial atherosclerotic disease (ICAD) treatments. In...
A tribute to the late Conrad Yiu was NeuroNews’ most read story in January, indicating the impact he has had and will likely continue to have on the stroke care community. The long-awaited publication of final results from the...
Basking Biosciences has announced the close of US$55 million in financing, which will be used to accelerate clinical development of its novel thrombolytic therapy for acute stroke. New investor ARCH Venture Partners led the round, with participation from additional new...
Medtronic has announced the first neurointerventional case in Europe with its Rist 6Fr radial access catheter, which recently received regulatory approval for use in European Union (EU) countries and other geographies accepting a CE mark. According to Riitta Rautio (Turku...
A research team led by City University of Hong Kong (CityU; Kowloon, Hong Kong) neuroscientists recently discovered that low-dose ionising radiation (LDIR), such as X-ray irradiation, can reduce lesion size and reverse motor deficits associated with traumatic brain injury...
InspireMD announced today that it has received CE-mark recertification under the European Union’s (EU) new Medical Device Regulation (MDR) regulatory framework for its CGuard embolic prevention system (EPS), which is a carotid stent device intended to facilitate the prevention...
Abbott recently announced that it has received approval from the US Food and Drug Administration (FDA) to launch the Liberta RC deep brain stimulation (DBS) system—the “world's smallest” rechargeable DBS device with remote programming, according to the company—to treat...
A team of physicians, neuroscientists and engineers at Duke University (Durham, USA) have reported multiple new strategies that use deep brain stimulation (DBS) to improve the symptoms of Parkinson’s disease. By simultaneously targeting two key brain structures and using...
The closing weeks of 2023 saw fresh findings comparing general anaesthesia (GA) to sedation in stroke thrombectomy disclosed for the first time, with leading researcher Peng Roc Chen (UTHealth Houston, Houston, USA) presenting results from the SEGA trial at...
Thanh N Nguyen, professor of neurology, radiology and neurosurgery at the Boston University Chobanian and Avedisian School of Medicine in Boston, USA, has been elected president of the Society of Vascular and Interventional Neurology (SVIN). Nguyen is the first...
Leica Microsystems has launched an evolved version of its ARveo 8 digital visualisation microscope for neurosurgery. The ever-growing ecosystem, ARveo 8, enhances surgical visualisation through the application of a 3D view and augmented reality (AR) fluorescence, as stated in...
Physicians at The Ottawa Hospital (TOH) in Ottawa, Canada recently became the first in the world to use a new stroke technology, the MicroAngioscope (Vena Medical), in a patient procedure. Equipped with “the world’s smallest camera”, the device goes...
Nalu Medical presented interim data from the “landmark” COMFORT randomised controlled trial (RCT)—indicating long-term and holistic pain management outcomes with its peripheral nerve stimulation (PNS) system—at the recent North American Neuromodulation Society (NANS) annual meeting (18–21 January, Las Vegas,...
At this year’s North American Neuromodulation Society (NANS) annual meeting (18–21 January, Las Vegas, USA), Medtronic announced new data from two clinical trials demonstrating the benefits of its spinal cord stimulation (SCS) technologies in patients with chronic low back...
Cerevasc has announced that data from clinical studies in the USA and Argentina examining the use of its eShunt system to treat communicating hydrocephalus were presented at the recent ABC WIN Seminar (15–20 January, Val d’Isère, France). Data from clinical studies of the...
As per an observational study published in the journal Neurology last year, female hormone therapy use may be associated with a higher risk of intracranial haemorrhage from cerebral cavernous malformations (CCMs)—raising questions about the safety of these therapies for...
The final publication of midterm results from the observational CARAS study suggest that cerebral ischaemic event (CIE) incidence in asymptomatic carotid stenosis patients “should not be underestimated”, so say authors Rodolfo Pini (University of Bologna, Italy) and colleagues, relaying...
Boston Scientific Corporation has announced positive one-year results from the SOLIS randomised controlled trial, demonstrating sustained pain relief using its WaveWriter Alpha spinal cord stimulation (SCS) systems for the treatment of non-surgical back pain (NSBP), presented at the recent...
Abbott has announced that the US Food and Drug Administration (FDA) has approved expanded magnetic resonance imaging (MRI) labelling for its dorsal root ganglion (DRG) stimulation therapy, the Proclaim DRG neurostimulation system, which allows patients to receive full-body MRI...
Arissa Medical has announced the enrolment of the first patients in its Syntra study—a first-in-human (FIH), early feasibility study evaluating the safety and efficacy of the company’s Syntra device for the treatment of wide-necked sidewall and wide-necked bifurcation cerebral...
A new study, published in the Journal of NeuroInterventional Surgery (JNIS) late last year, has assessed the safety of the latest iteration of the Pipeline Vantage embolisation device (Medtronic) in the treatment of unruptured intracranial aneurysm patients—ultimately producing “acceptable...
Medtronic has announced the US Food and Drug Administration (FDA) approval of its Percept RC deep brain stimulation (DBS) system. The rechargeable neurostimulator is the latest innovation in the Medtronic Percept family, which includes the Percept PC neurostimulator, BrainSense technology...
Nevro Corporation has announced a series of data presentations supporting the use of the company's high-frequency (HFX) 10kHz spinal cord stimulation (SCS) therapy for patients with chronic pain—set to be presented at this week’s North American Neuromodulation Society (NANS)...
Saluda Medical has announced that its data will be presented at the upcoming North American Neuromodulation Society (NANS) annual meeting (18–21 January, Las Vegas, USA). With the company’s three-year EVOKE study having demonstrated superior pain relief in its closed-loop arm...
SPR Therapeutics has announced that it is set to be featured prominently at the upcoming North American Neuromodulation Society (NANS) annual meeting (18–21 January, Las Vegas, USA). A total of 11 abstracts highlighting applications of the SPRINT peripheral nerve stimulation...
Boston Scientific Corporation has announced its clinical data that will be featured at the upcoming North American Neuromodulation Society (NANS) annual meeting (18–21 January, Las Vegas, USA). A total of 19 abstracts from the company’s chronic pain and deep...
Route 92 Medical has announced the company’s 100th global issued patent for its innovative neurovascular intervention product portfolio, as per a press release. The company offers a range of solutions for neurovascular interventional procedures, including its FreeClimb catheter systems...
Neuralace Medical has announced the US Food and Drug Administration (FDA) clearance of its “groundbreaking” Axon therapy for the treatment of chronic painful diabetic neuropathy (PDN). This “landmark approval” marks the first ever FDA clearance of a non-invasive, magnetic...
Carotid artery stenting (CAS) delivered via transradial artery access has demonstrated no increased risk of stroke, death, myocardial infarction, transient ischaemic attack, or access site complications, as compared to the more traditional transfemoral approach. That is the concluding finding...
In a recent study from the USA now published in the journal Neurology, Black people consistently had a higher rate of stroke than white people over a 22-year period. The same study also found that the average age of...
Extolling the benefits of evidence-based practice, timely surgical intervention and intensive medical therapy, Dominic PJ Howard (Oxford, UK) spoke at the recent Vascular Society of Great Britain and Ireland’s (VSGBI) annual scientific meeting (VSASM 2023; 22–24 November, Dublin, Ireland)...
Arissa Medical has announced the successful evaluation of the Syntra intrasaccular scaffold system within simulated use conditions under fluoroscopy using clinically relevant, in-vitro intracranial aneurysm models provided by the Jacobs Institute in Buffalo, USA. The Syntra INR user study evaluated...
Mentice recently announced that Ankyras, the company’s clinical decision support application, has received 510(k) clearance from the US Food and Drug Administration (FDA). The approval of this product by the FDA demonstrates the safety and effectiveness of Ankyras, and...
Final results from the PROST randomised controlled trial (RCT) have been published in JAMA Neurology and—according to the study’s leading investigators—provide evidence that thrombectomy with the Preset stent retriever (Wallaby/Phenox) is a safe and effective option in large vessel...
In light of recent evidence indicating that thrombectomies with poor reperfusion may lead to inferior clinical outcomes versus medical management in ischaemic stroke, Adrien Guenego (Brussels, Belgium) assesses the need for a “fundamental change” over decision-making and how success...
Hyperfine has announced the launch of the artificial intelligence (AI)-powered eighth generation of its Swoop system software. “The software update on the Swoop system has been most beneficial to our workflow,” said Jennifer Villa Frabizzio (Radiology Group of Abington, USA). “We...
A device labelled “the third way” to potentially treat intracranial aneurysms via an intrasaccular approach has demonstrated positive effectiveness and safety results at one year in a first-in-human (FIH) study, as per a presentation at the Barts Research and...
The recent Barts Research and Advanced Interventional Neuroradiology (BRAIN) conference (4–6 December 2023, London, UK) saw Tommy Andersson (Karolinska University Hospital, Stockholm, Sweden) put forward the case for post-thrombectomy rescue stenting in ischaemic strokes caused by challenging, neutrophil extracellular...

Phil White

Phil White’s career as a physician and researcher has seen him play a role in numerous major stroke trials, and serve as an educator to many in the interventional neuroradiology (INR) space via the European Course in Minimally Invasive...
GE HealthCare has entered into an agreement to acquire MIM Software, a provider of artificial intelligence (AI)-enabled image analysis and workflow tools across multiple care areas, including oncology, urology, neurology, and cardiology. GE HealthCare expects to leverage MIM Software’s imaging...
Axonics has announced that it has entered into a definitive agreement to be acquired by Boston Scientific Corporation for US$71 in cash per share, representing an equity value of approximately US$3.7 billion. Axonics brings a complementary product portfolio to the...
SynerFuse has announced the appointment of Rohan Lall (M Health Fairview Neurosurgery, Princeton, USA) as the company’s chief medical officer. The appointment was effective on 2 January 2024. “Dr Lall has been instrumental in SynerFuse progressing to where we are...
Rescue stent placement following a failed thrombectomy procedure has demonstrated “good outcomes” and a low risk of clinically significant bleeding in a multiethnic cohort of acute ischaemic stroke patients from the Middle East, Africa and Asia. Writing in the...
Evasc Neurovascular has announced new strategic growth initiatives, having recently achieved a milestone of 120 successful cerebral aneurysm cases with its innovative Eclips device. The Canada-based company is also expanding its European operations with the establishment of a new...
Multiple new pieces of major trial data presented at the Society of Vascular and Interventional Neurology (SVIN) annual meeting (16–18 November 2023, Miami, USA) feature across NeuroNews’ 10 most popular stories from December. Insights on intracranial aneurysm care—including a...
An international panel of clinical researchers has published a report in the journal Stroke in which they advocate “immediate change” regarding treatment protocols for intracranial haemorrhage (ICH), citing the fact that haemorrhagic stroke management “lags far behind” that seen...
NeuroPace has announced the completion of the patient enrolment goal in its NAUTILUS pivotal study for the treatment of idiopathic generalised epilepsy (IGE) “more than one quarter ahead of schedule”, according to a company press release. “We are extremely proud...
In an editor's column published recently in the Journal of NeuroInterventional Surgery (JNIS), leading members of the Society of NeuroInterventional Surgery (SNIS) have argued that the entire body of research, including new evidence from two prospective clinical trials, “clearly confirms” that most patients...
Perfuze has announced US Food and Drug Administration (FDA) clearances for the Millipede 070 aspiration catheter and the second-generation of its Millipede 088 access catheter. The first of these devices, the Millipede 070 aspiration catheter, is intended to remove blood...
Conrad Yiu, a pioneer and visionary in interventional ischaemic stroke therapy, passed away in the final weeks of 2023, succumbing to the very disease for which he so fervently sought to enable and advance treatment. In a guest piece for...
Researchers in The Netherlands have received a Horizon grant worth €10 million from the European Commission to accelerate development of a technology that could allow operators to assess the best treatment for a patient with a cerebral infarction or...
Nicolab has announced that its computed tomography (CT) perfusion algorithm, which is integrated into the company’s StrokeViewer platform, has obtained 510(k) clearance from the US Food and Drug Administration (FDA). Nicolab’s StrokeViewer solution is also set to be deployed...
The US Securities and Exchange Commission (SEC) has today charged Laura Tyler Perryman—the former chief executive officer (CEO) and co-founder of Florida-based medical device startup Stimwave Technologies—with defrauding investors out of approximately US$41 million by making “false and misleading...
This advertorial is sponsored by Medtronic. As part of the company’s ongoing commitment to offering physicians access to high-quality clinical data and, subsequently, enabling evidence-based practice to flourish, Medtronic has established a global registry—dubbed ‘INSPIRE-S’—producing real-world findings relating to the...
As per a recent statement from the North American Neuromodulation Society (NANS), the US state of Washington may be about to extend its insurance coverage policies relating to spinal cord stimulation (SCS) therapies. Washington’s Health Technology Clinical Committee recently conducted...
Imperative Care has announced the initiation of a first-in-human (FIH) clinical study for its novel stent system designed to only require single antiplatelet therapy for patients undergoing stent-assisted treatment of wide-neck intracranial aneurysms. The first three patients enrolled were successfully...
This advertorial is sponsored by Medtronic. As the co-founder and chief executive officer of Chestnut Medical, Aaron Berez played a leading role in bringing flow diverters to market with the development of the Pipeline embolisation device (Medtronic) for intracranial aneurysm...
Researchers from the Medical University of South Carolina (MUSC) have partnered with US emergency medical services (EMS) to pilot test the first magnetic resonance imaging (MRI)-equipped ambulance in an effort to speed up stroke response. The researchers concluded a...
NeuroOne Medical Technologies Corporation has announced that it has received US Food and Drug Administration (FDA) 510(k) clearance to market its OneRF ablation system for creation of radiofrequency lesions in nervous tissue for functional neurosurgical procedures. “When NeuroOne was founded, one...
Neuspera Medical recently announced it has completed patient enrolment and implant procedures for the SANS-UUI pivotal clinical trial of its Neuspera system—a discreet, minimally invasive implant designed to provide patients with personal control and relief from urinary urge incontinence...
BCV has announced that it has secured €6 million in a Series A round of financing led by Forepont Capital Partners, with other investors including NTI, MEDCO and existing French investors. This Series A funding brings the total amount...
Across October and November, our readers were drawn to everything from recent shifts in neurovascular device regulation, to “failures of the peer-review process” in intracranial aneurysm literature, to the latest major trial supporting thrombectomy for large-infarct ischaemic strokes. Among...
Rapid Medical has announced Japanese approval for its Tigertriever revascularisation device. With Pharmaceuticals and Medical Devices Agency (PMDA) approval, Tigertriever serves as “the first device to offer individualised solutions for mechanical thrombectomy”, a Rapid press release claims. Kaneka Corporation has...
This advertorial is sponsored by Medtronic. As a prospective, independently adjudicated registry boasting a highly comprehensive patient dataset, INSPIRE-A is a “very unique” phenomenon in the field of endovascular aneurysm care—and one that may be able to provide answers for...
Philips has announced that, on 29 November 2023, the WE-TRUST study enrolled its 100th patient, marking what the company describes as an “important milestone” in the target of enrolling more than 500 stroke patients by the end of 2024....

NeuroNews issue 52 – US

Highlights: Physicians posit that equipoise likely remains between general anaesthesia and conscious sedation in endovascular therapy following the presentation of SEGA trial results at the Society of Vascular and Interventional Neurology (SVIN) annual meeting (16–18 November 2023, Miami, USA) ...

NeuroNews issue 52 – OUS

Highlights: Physicians posit that equipoise likely remains between general anaesthesia and conscious sedation in endovascular therapy following the presentation of SEGA trial results at the Society of Vascular and Interventional Neurology (SVIN) annual meeting (16–18 November 2023, Miami, USA) ...
SpineX has announced that it is close to full recruitment of the patient cohort for a clinical trial of its proprietary SCONE device, recently passing the 80% mark. SCONE is an innovative device that treats urinary incontinence, allowing people...
Q’Apel Medical has launched a new-generation aspiration technology, the 072 Hippo aspiration system, which has been developed for patients suffering from a stroke due to a large vessel occlusion. The recently US Food and Drug Administration (FDA)-cleared stroke system—comprised of...
Fresh data from the SOFAST study have indicated high rates of technical success and first-pass reperfusion with the Sofia 6Fr Flow Plus aspiration catheter (Microvention/Terumo), indicating that the device is both safe and effective in large vessel occlusion (LVO)...
Nevro Corporation has announced that it has acquired Vyrsa Technologies—a privately held medical technology company focused on a minimally invasive treatment option for patients suffering from chronic sacroiliac (SI) joint pain. Under the terms of the transaction, which signed and...
A “historical milestone” for stroke patients in Brazil was achieved recently, with the country’s Ministry of Health (MOH) publishing Order 1.996/2023 on 24 November to add mechanical thrombectomy to the list of procedures covered by the Brazilian public health...
This advertorial, sponsored by Siemens Healthineers and intended for US readers only, is part of a series of articles on the emerging role for neurovascular office-based labs (OBLs). Neurovascular diseases present formidable obstacles for both patients and healthcare providers. As...
Kaneka Corporation has acquired all shares of Japan Medical Device Technology and has made it a wholly owned subsidiary. Kaneka manufactures and sells endovascular catheters, which are devices used in the treatment of cardiac, peripheral vascular and cerebrovascular diseases. Kaneka is...
Nalu Medical has announced the publication of the spinal cord stimulation (SCS) nPower US clinical study in the Pain Physician Journal, reporting on clinical outcomes related to the use of the Nalu SCS system to treat patients suffering from chronic...
A comparative study recently demonstrated the promise held by PreSize Neurovascular (Oxford Heartbeat) software in consistently and accurately making predictions about flow-diverter placement in intracranial aneurysm treatments. However, according to lead study author Ansaar Rai (West Virginia University Rockefeller...
Intra-arterial tenecteplase has demonstrated potential as a safe and feasible adjunct to mechanical thrombectomy in patients with acute ischaemic stroke caused by a distal large vessel occlusion (LVO) who achieve “successful but incomplete” reperfusion, as per findings from the...
Theranica has announced the peer-reviewed publication of a comprehensive clinical study showing the preventive benefits of its remote electrical neuromodulation (REN) wearable, Nerivio, for adolescents suffering from migraine. The study—published in Frontiers in Pain Research—demonstrates that frequent use of...
In a guest piece for NeuroNews, Arūnė Simanavičienė (Kaunas, Lithuania) and Audrius Širvinskas (Vilnius, Lithuania) highlight the work being done by the Brain Aneurysm Foundation in Lithuania, and its attempts to boost awareness of the finer details of intracranial...
The multicentre, randomised SEGA trial has found that acute ischaemic stroke patients who receive endovascular therapy (EVT) under general anaesthesia experience better functional outcomes at 90 days compared to those who receive the procedure under conscious sedation. These results—presented for...
Researchers from Germans Trias i Pujol Research Institute (IGTP; Badalona, Spain) have discovered that administering human apotransferrin to mice affected by intracranial haemorrhage (ICH) can mitigate the damaging effects of this severe type of stroke. Findings from an experimental...
Receiving intravenous tissue plasminogen activator (IV-tPA) in an ambulance-based mobile stroke unit (MSU) increases the likelihood of averting strokes and the odds of a patient achieving complete recovery compared with standard hospital emergency care, according to researchers at Weill...
Brainomix has heralded its continued US expansion with the launch of a full suite of US Food and Drug Administration (FDA)-cleared modules in its Brainomix 360 platform for stroke care. The US launch—which included the company’s previously announced, FDA-cleared e-ASPECTS...
Nevro Corporation has announced the publication of new 24-month data from the SENZA-NSRBP multicentre randomised controlled trial (RCT) in the Journal of Neurosurgery: Spine. The published 24-month data detail outcomes for non-surgical refractory back pain (NSRBP) patients treated with Nevro's...
Route 92 Medical has announced it has raised more than US$31 million in a Series F financing round to accelerate the commercial adoption of a neurovascular intervention portfolio focused on acute ischaemic stroke. The oversubscribed capital raise was led...
Neurolutions and Kandu Health recently announced a strategic partnership intended to raise the standard of care for post-stroke recovery. Through this partnership, Kandu’s expert clinicians will support Neurolutions by providing clinical consultation and assessments of stroke survivors to determine...
Boston Scientific Corporation has announced the close of its acquisition of Relievant Medsystems—the company behind the US Food and Drug Administration (FDA)-cleared Intracept intraosseous nerve ablation system, which is used to treat a form of chronic low back pain...
The ATTEST-2 trial has found that tenecteplase was non-inferior to alteplase, the more established of the two thrombolytic agents, in suitable acute ischaemic stroke patients. Preliminary results from the study were presented by principal investigator Keith Muir (University of...
Rapid Medical has announced new data demonstrating “excellent” first-pass treatment success using the Tigertriever device in complex ischaemic stroke patients with underlying intracranial atherosclerotic disease (ICAD). The complication rates were also negligible, as reported at the ongoing Society of Vascular and...
Microvention, a wholly owned subsidiary of Terumo Corporation, is celebrating a decade of legacy innovation commemorating the anniversary of its Sofia and Sofia Flow Plus aspiration catheters, having performed more than half a million worldwide procedures across 170 countries,...
Route 92 Medical has announced new results from a multicentre clinical study evaluating the efficacy, safety and efficiency of the Tenzing 7 delivery catheter as a means for delivering therapeutic devices for mechanical thrombectomy in acute ischaemic stroke. The results—now published in Stroke:...
A systematic review and meta-analysis of 1,356 studies and more than 410,000 patients have found that “methodological flaws and incomplete reporting” occur frequently in studies advocating the safety, effectiveness or durability of intracranial aneurysm treatments—forming a “potential public health...
The proliferation of new technologies and advancements in the neurosciences space has showed little sign of slowing in recent years and—as John Rolston (Boston, USA) avers in this guest piece for NeuroNews—patients with brain function diseases may well reap...
With a renewed focus on challenging cases, novel technologies and, overall, the most pressing issues in carotid treatments and acute stroke care, the 2024 Charing Cross (CX) Symposium (23–25 April, London, United Kingdom) intends to maximise audience participation throughout...
People who live in neighbourhoods with lower socioeconomic status are less likely to receive clot-busting medications or undergo mechanical thrombectomy procedures after they have a stroke compared to those living in neighbourhoods with a higher socioeconomic status. That is...
SpineX has reported in a press release that a publication titled, “A pilot study of the effect of transcutaneous spinal cord stimulation on micturition-related brain activity and lower urinary tract symptoms after stroke”, has been accepted by the Journal...
RapidAI announced today that it has received US Food and Drug Administration (FDA) clearance for Rapid SDH, its artificial intelligence (AI)-powered module for the detection and notification of suspected hemispheric acute and chronic subdural haematoma (SDH). Together with Rapid ICH and Rapid Hyperdensity, both...
Rapid Medical has announced that the final patient has been enrolled in SUCCESS—a US Food and Drug Administration (FDA) post-market surveillance study assessing the safety and performance of the company's Comaneci embolisation assist device in the USA. The final patient...
The principle of medical necessity “should drive all remote monitoring decisions” relating to spinal cord stimulation (SCS) technologies, according to recommendations recently published in Neuromodulation: Technology at the Neural Interface by a panel of pain management experts. The panel...
Surgical Information Sciences (SIS) has announced the commencement of its post-market VISION study evaluating visualisation of the subthalamic nucleus (STN) and globus pallidus internus (GPi) for deep brain stimulation (DBS) surgery in patients with Parkinson's disease. This study aims to...
Perfuze has announced commencement of enrolment in its pivotal MARRS study—a multicentre trial set to evaluate the performance of aspiration thrombectomy with the company’s Millipede system for revascularisation in acute ischaemic stroke. The first patient was enrolled at Stony...
InspireMD recently presented 30-day results from the C-GUARDIANS US investigational device exemption (IDE) clinical trial evaluating its CGuard embolic prevention stent (EPS) system for stroke prevention at the annual Vascular Interventional Advances (VIVA) meeting (30 October–2 November 2023, Las...
New results from the TENSION study—presented recently at the 15th World Stroke Congress (WSC; 10–12 October, Toronto, Canada) by Götz Thomalla (University Medical Center Hamburg-Eppendorf, Hamburg, Germany)—have demonstrated improved functional outcomes and reduced mortality rates among stroke patients treated...
Contego Medical has announced the presentation of late-breaking clinical results from the PERFORMANCE II carotid stent trial at the annual Vascular Interventional Advances (VIVA) meeting (30 October–2 November 2023, Las Vegas, USA). PERFORMANCE II is a prospective, multicentre study...
Annalise.ai has announced the launch of Annalise Triage—an innovative software solution tailored specifically for the US market that the company claims will “transform the radiology field by empowering radiologists to efficiently triage studies and prioritise those with suspected critical...
A study demonstrating the successful deep-brain placement of a brain-computer interface (BCI) microchip into a living animal with no apparent neurological effects has been published in the journal Brain-Computer Interfaces, as per a press release from NICO Corporation. The publication—led...
In a “notable departure” from prior iterations of the conference, this year’s Society of Vascular and Interventional Neurology (SVIN) annual meeting (16–18 November, Miami, USA) will place a “distinct emphasis” on innovation, focusing on the latest technologies within interventional...
There are multiple components of the PROST randomised controlled trial’s (RCT) design that set it apart from prior studies and make it somewhat unique in the stroke thrombectomy space. At this year’s European Society of Minimally Invasive Neurological Therapy...
Surmodics has announced the commercial launch of its most advanced hydrophilic medical device coating technology, the Preside hydrophilic coatings. As per a company press release, Preside hydrophilic coatings complement Surmodics’ existing Serene hydrophilic coatings by providing customers with a unique,...
MindRhythm has announced that the US Food and Drug Administration (FDA) has awarded a Breakthrough Device designation to its Harmony headset embedded with HeadPulse technology. “This designation highlights the position that Harmony is truly breakthrough, as it acknowledges the...
A secondary analysis of existing clinical trial data has indicated that new ischaemic brain lesions detected via diffusion-weighted magnetic resonance imaging (DW-MRI) following carotid artery revascularisation—either with carotid artery stenting (CAS) or carotid endarterectomy (CEA)—do not appear to have...
In a new case report, researchers at University of California Los Angeles (UCLA) Health have described “promising results” using repetitive transcranial magnetic stimulation (rTMS) in the management of post-stroke cerebellar ataxia—a debilitating condition marked by impaired coordination and balance. Ataxia...
Recently published data from two large randomised controlled trials (RCTs) have indicated there may be minimal benefits—or even negative effects—associated with bypassing local or primary stroke centres (PSCs) and transporting patients straight to thrombectomy-capable comprehensive stroke centres (CSCs). However,...
Cordance Medical has announced that its device, NeuroAccess, has been granted Breakthrough Device designation by the US Food and Drug Administration (FDA), meaning the company will receive prioritised review and accelerated interaction with the regulator. The NeuroAccess device is engineered...
Ahead of World Stroke Day 2023, on 29 October, physicians from the Get Ahead of Stroke campaign are highlighting the fact that, while prevalence of stroke in the USA is declining in adults aged 75 years and older, it...
EOSolutions Corporation has announced that the US Food and Drug Administration (FDA) has cleared its Thinline introducer sheath—an approval that swiftly follows the successful launch of the company’s “revolutionary” Dr Banner balloon guide catheter (BGC) in the USA. The Thinline...
Cognito Therapeutics has announced that continued active treatment with the company’s gamma sensory stimulation technology in the Phase 2 OVERTURE open label extension (OLE) study demonstrated durability and concordance of clinical and magnetic resonance imaging (MRI) benefits over 18...
Digital health company Butterfly Network and deep tech research firm Forest Neurotech announced yesterday that they have entered into a five-year co-development agreement to further the development of next-generation brain-computer interfaces (BCIs) using Butterfly’s semiconductor-based Ultrasound-on-Chip technology. The agreement includes...
While the latest thrombectomy techniques, thrombolytic drug candidates and even neuroprotective agents are the source of much discussion in today’s neurovascular space, there is also significant room for improvement within another step along the stroke care pathway: patient triage....
Researchers at the UK Dementia Research Institute (DRI) have developed a new form of deep brain stimulation (DBS) that does not require surgery and could provide an alternative treatment option for brain diseases like Alzheimer’s. The technology—based on temporal interference...
A specialised ‘brain-wave cap’, designed by researchers in The Netherlands, may be able to diagnose stroke patients while they are in an ambulance—thus allowing them to receive appropriate treatments more quickly. "Our research shows that the brain-wave cap can recognise...
Robocath has today announced the results of its CARE clinical trial focusing on robotic carotid stenting—the first phase of a research programme launched in July 2021 by Robocath and Rennes University Hospital (Rennes, France), which, in the long term,...
SynerFuse has announced that it has completed enrolment in its proof-of-concept study to evaluate the safety and tolerability of the Electric Transforaminal Lumbar Interbody Fusion (e-TLIF) procedure integrating spinal fusion with direct nerve stimulation, which is designed to treat...
The third Stroke Recovery and Rehabilitation Roundtable—an initiative of the International Stroke Recovery and Rehabilitation Alliance (ISRRA)—has made a series of key recommendations about managing fatigue, measuring mobility, harnessing non-invasive brain stimulation technologies, and improving how trials are designed,...
The existing body of evidence supporting artificial intelligence (AI) and the autonomous navigation of endovascular procedures is “inadequate”, despite the theoretical benefits held by this “promising” concept. This is among the concluding messages delivered by Thomas Booth (Kings College Hospital,...
Administering 10Hz cerebellar repetitive transcranial magnetic stimulation (rTMS) offers a “promising”, non-invasive treatment option in patients experiencing dysphagia following a subacute infratentorial stroke, as per the findings of a recent randomised controlled trial (RCT). Writing in the journal Brain Stimulation,...
Anaconda Biomed has announced that the European Patent Office has granted the company a European patent for “A device and a thrombectomy apparatus for extraction of thrombus from a blood vessel”, published as patent number EP 3866708 B1 on...
Imperative Care recently announced the publication of clinical data in the journal Interventional Neuroradiology (INR) detailing the use of its Zoom aspiration catheters in patients with large and medium vessel occlusion stroke. Data from an independent study evaluating real-world experiences...
Athersys has announced that the independent data safety monitoring board (DSMB) has completed a preplanned interim analysis of the company’s ongoing, phase three MASTERS-2 pivotal clinical trial evaluating MultiStem (invimestrocel) for the treatment of moderate-to-severe acute ischaemic stroke. The...
Discussions at this year’s European Society of Minimally Invasive Neurological Therapy (ESMINT) congress (4–6 September, Marseille, France) revealed the extent of the disparities between the current regulatory systems in Europe and the USA, with experts and attendees outlining how “the...
The Nautilus system (Endostream Medical)—a self-conforming intrasaccular flow diverter intended for the treatment of intracranial aneurysms—heralds the “next evolution” in these types of neurovascular devices. That is according to J Mocco (Mount Sinai, New York, USA), who spoke to...
Boston Scientific has announced that the US Food and Drug Administration (FDA) has approved an expanded indication of the WaveWriter Alpha spinal cord stimulator (SCS) systems for the treatment of painful diabetic peripheral neuropathy (DPN), a complication of diabetes...
Brainomix and Nanoflex Robotics have announced today that they have been awarded a grant via the ‘UK—Switzerland Bilateral: Collaborative R&D ’ programme, under which the companies will work together to jointly develop an integrated remote diagnosis and treatment platform...
While sex disparities regarding the outcomes of carotid revascularisation have “long been a concern”, new prospective data published in the Journal of Vascular Surgery (JVS) indicate that no such disparity exists between male and female patients treated with transcarotid...
NeuraSignal has announced the publication of positive results from the BUBL clinical study supporting the safety and superior performance of its NovaGuide intelligent ultrasound system in detecting right-to-left shunt (RLS)—often due to a patent foramen ovale (PFO)—in patients with...
Royal Philips and the World Stroke Organization (WSO) have announced the signing of a two-year partnership aimed at improving access to high-quality stroke care. Building on their shared commitment to delivering improvements in stroke prevention, treatment, rehabilitation and support, Philips...
Hyperfine has announced US Food and Drug Administration (FDA) clearance of updated software for its portable magnetic resonance brain imaging technology, the Swoop system. Built on a “robust” artificial intelligence (AI) foundation, the latest software brings image-quality enhancements to...
Between now and 2050—unless “urgent action is taken”—the number of people who die from stroke globally is estimated to increase by 50%, to 9.7 million deaths per year, with annual costs as high as US$2.3 trillion also a possibility....
Roger Malcolm Greenhalgh, the surgeon internationally renowned for his unparalleled contribution to vascular education, training and research, died peacefully on 6th October, aged 82. At the time of his death, he was emeritus Professor of Surgery at Imperial College...
Contego Medical has announced enrolment of the first patient in the prospective, multicentre PERFORMANCE III trial aimed at further evaluating the safety and effectiveness of the Neuroguard integrated embolic protection (IEP) direct system—a carotid stent system designed for direct transcarotid...
Exclusive interviews with multiple pioneering figures in the US neurovascular field earmark NeuroNews’ latest top 10, as do results from two ongoing studies attempting to elucidate mechanical thrombectomy and its place alongside other therapies in acute ischaemic stroke. A...
Biotronik Neuro has announced that results from the BENEFIT-02 trial—the “first of its kind” to clinically evaluate a multiphase stimulation paradigm—support the effectiveness of RESONANCE multiphase stimulation used in the company’s Prospera spinal cord stimulation (SCS) system for the...
A study recently published in the journal Neurology investigated whether there are discrepancies in the prognosis of subarachnoid haemorrhage (SAH) patients between the university hospital districts in Finland—and has revealed “surprising” regional differences, according to lead author Aleksanteri Asikainen (University...
Medtronic has shared that Paolo Di Vincenzo will join the company as president of its neuromodulation business, effective 30 October 2023. In this role, Di Vincenzo will be responsible for the overall strategic direction of the Medtronic neuromodulation business...
The North American Neuromodulation Society (NANS) has led a multi-society response to the Washington State Health Care Authority (WSHCA) following its review of the current evidence on spinal cord stimulation (SCS). As per a NANS press release, the state of...
Transradial access, whereby the vasculature is navigated to via the radial artery in the wrist, has been a topic of much debate in the neurovascular space over the past few years. Despite demonstrating promising advantages and being advocated for...
A new study has shed fresh light on the potential connection between pre-existing heart issues and symptoms of ‘long-COVID’. According to researchers from New York University (NYU) Langone Health in New York City, USA, being infected with the pandemic...
This advertorial, intended for US readers only, is sponsored by CERENOVUS. “Going distally with guide catheters is more routine nowadays,” says Violiza Inoa (Memphis, USA), discussing what she sees as a relatively recent shift in the way many physicians choose...
A young neurosurgeon and researcher from Buffalo, USA has been awarded US$150,000 via the Congress of Neurological Surgeons (CNS) Foundation/Cerebrovascular (CV) Young Investigator Grant to study the reasons why women develop a higher rate of cerebral aneurysms compared to...
Remote teleproctoring has demonstrated promising results in providing hands-on mechanical thrombectomy training and overcoming wartime migration restrictions in Ukraine, according to initial experiences published recently in the journal Interventional Neuroradiology. “Teleproctoring brings together specialists who are engaged in INR all around the...

NeuroNews issue 51 – US

Highlights: New data that "refute" the seminal ARUBA trial's conclusions on interventional treatments for arteriovenous malformations (AVMs) as well as several other highlights from this year's Society of NeuroInterventional Surgery (SNIS) annual meeting (31 July–4 August, San Diego, USA) ...

NeuroNews issue 51 – OUS

Highlights: New data that "refute" the seminal ARUBA trial's conclusions on interventional treatments for arteriovenous malformations (AVMs) as well as several other highlights from this year's Society of NeuroInterventional Surgery (SNIS) annual meeting (31 July–4 August, San Diego, USA) ...
“The possibility to restore mobility to patients could have tremendous benefits,” says Mitchell Elkind, chief clinical science officer of the American Heart Association (AHA), and a tenured professor of neurology and epidemiology at Columbia University (New York City, USA),...
Cerevasc has announced that data from clinical studies examining the use of its eShunt system to treat elderly patients with normal-pressure hydrocephalus, and patients with communicating hydrocephalus following treatment for a ruptured cerebral aneurysm, were recently presented at the Congress...
Saluda Medical has announced that the US Food and Drug Administration (FDA) has approved magnetic resonance imaging (MRI) conditional labelling for its Evoke system, which the company claims is “the first and only” precision, dose-control spinal cord stimulation (SCS)...
Onward Medical has today announced the successful first-in-human implant of its ARC-IM stimulator intended to restore upper-extremity function after spinal cord injury (SCI). The implanted patient also received a wireless brain-computer interface (BCI) designed to initiate thought-driven movement when...
The Brain Aneurysm Foundation (BAF) has announced the recipients of its 2023 research grants, providing support to academic researchers studying the underlying biology of aneurysms or developing new treatment methods. This year's grantees include leading academic researchers from across the USA and Canada whose...
New data from an analysis of patients who would have been eligible for the ARUBA trial—which previously indicated medical management is likely favourable over intervention in unruptured arteriovenous malformation (AVM) treatment—have produced results contradicting this seminal study, and look...
Data from the US Vascular Quality Initiative (VQI) have indicated that younger patients (aged ≤55 years) who undergo a carotid endarterectomy (CEA) procedure face an increased likelihood of carotid disease recurrence and late neurological events, as compared to their older...
Cerevasc has announced that the US Food and Drug Administration (FDA) has approved an investigational device exemption (IDE) supplement to permit the expansion of a study of its eShunt system in patients with normal-pressure hydrocephalus (NPH) to additional study...
Vesalio has announced the recent presentation of key findings from the CLEAR study—a prospective, multicentre, open-label, single-arm, US Food and Drug Administration (FDA)-regulated investigational device exemption (IDE) trial evaluating the safety and effectiveness of the company’s Neva thrombectomy device,...
Given the potentially devastating consequences that can occur if an ischaemic stroke or acute intracranial aneurysm procedure goes wrong, an interventional neuroradiologist’s practice is inherently pressurised and extraordinarily demanding—even relative to the average physician. To gain insights on how...
Nevro Corporation has announced the publication of new data validating the health economic benefits of 10kHz therapy, the company’s proprietary, high-frequency spinal cord stimulation (SCS) therapy, in both painful diabetic neuropathy (PDN) and non-surgical refractory back pain (NSRBP). These...
Microvention, a wholly owned subsidiary of Terumo Corporation, announced today that the Sofia EX 5Fr 115cm intracranial support catheter received US Food and Drug Administration (FDA) 510(k) clearance on 15 September 2023 for use in transradial access in addition...
Sheba Medical Center in Tel Aviv, Israel has revealed the results from a “groundbreaking” study in the International Journal of Emergency Medicine, validating an artificial intelligence (AI) algorithm developed by Aidoc for intracerebral haemorrhage (ICH) detection. The study demonstrated that machine...
To help “close the gap between knowledge and action”, the American Stroke Association (ASA) is launching a culturally relevant Spanish-language campaign named ‘Juntos Contra el Derrame Cerebral’ to raise awareness among Spanish-dominant audiences around the use and understanding of...
Motif Neurotech, a company developing minimally invasive bioelectronics for mental health conditions, has announced new research published to the preprint server Medrxiv that demonstrates the use of a millimetre-sized brain stimulator—the prototype Motif DOT microstimulator—in a human subject. The study was a...
Route 92 Medical has announced the appointment of Jonathan Kennedy to the role of chief financial officer. In this role, Kennedy will be responsible for overseeing all financial management for the company, reporting directly to CEO and founder Tony...
Boston Scientific Corporation has today announced it has entered into a definitive agreement to acquire Relievant Medsystems—a privately held medical technology company that has developed and commercialised the Intracept intraosseous nerve ablation system to treat a form of chronic...
Cerevasc has today announced that findings from a clinical study examining the use of its eShunt system to treat communicating hydrocephalus were recently presented at the 2023 European Society of Minimally Invasive Neurological Therapy (ESMINT) congress (4–6 September, Marseille,...
Theranica has announced the results of a study, recently published in the journal Pain Management, suggesting the rapid impact of Nerivio—the first and only migraine ‘neuroband’, according to the company—in reducing numbers of migraine days. A previous study had already...
The Congress of Neurological Surgeons (CNS) Foundation has launched its Pathway to Neurosurgery programme, an initiative dedicated to alleviating healthcare disparities by encouraging high school students from underrepresented groups to pursue a career in neurosurgery or medicine. "This unique programme...
The Brain Aneurysm Foundation (BAF) has announced the launch of ‘Stop the Pop’—a new campaign intended to increase awareness of the prevalence and impact of brain aneurysms, and the need for ongoing investment to fund new innovations, screening, and...
Several presentations and news stories from this year’s Society of NeuroInterventional Surgery (SNIS) annual meeting (31 July–4 August, San Diego, USA) ended up among our most-read articles in August. Additionally, exclusive insights on intracranial aneurysm treatments—offered by a globally...
Synchron has announced completion of patient enrolment in the USA-based COMMAND trial assessing the company’s endovascular brain-computer interface (BCI) technology. “Giving patients the option to receive a BCI device without the need for open brain surgery could open up a...
There are likely to be minimal differences in clinical outcomes between acute stroke patients presenting directly to endovascular treatment centres who undergo mechanical thrombectomy alone, and those who receive intravenous thrombolysis (IVT) plus thrombectomy. That is according to a...
Two separate systematic reviews and meta-analyses—both published recently in Neuromodulation: Technology at the Neural Interface—have concluded that intrathecal drug delivery (IDD) systems are effective in the management of cancer-related pain, with one report also finding an average reduction in...
When it comes to advising young physicians on how to navigate the more commercial, industry-entwined commitments that their career will most likely bring further down the line, there are few better-placed physicians than Ajay Wakhloo (Burlington, USA)—an interventional neuroradiologist-turned-inventor...
This advertorial, intended for readers outside the USA only, is sponsored by Penumbra. Much of the clinical success that can be achieved with aspiration-based mechanical thrombectomy is dependent on the characteristics and features of the specific device being used. In...
This advertorial is sponsored by Medtronic. Alberto Nania (National Health Service Lothian, Edinburgh, UK) speaks to NeuroNews to outline how, despite the rapid proliferation of new technologies and clinical data in the interventional neuroradiology (INR) space over the past...
 Female representation in the neurointerventional world may be growing, but Johanna Fifi (Mount Sinai, New York, USA) and Anne-Christine Januel (Toulouse University Hospital, Toulouse, France) believe much more work can—and will—be done to carry this even further in the...
Endovascular therapy (EVT) treatments that achieve poor reperfusion have been found to result in inferior clinical outcomes compared to best medical management (BMM) in large vessel occlusion (LVO) acute ischaemic stroke patients. That is according to a substudy of the...
Rapid Medical has announced Chinese National Medical Product Administration (NMPA) approval for its adjustable Tigertriever revascularisation device, making it the first device to offer patient-specific solutions for removing blood clots from the brain to advance the treatment of ischaemic...
ameer hassan

Ameer Hassan

Having initially sought out a career in plastic surgery, Ameer Hassan (Harlingen, USA) switched gears to interventional neurology in 2005—a change of heart he attributes to his “greatest mentor”—and never looked back. In addition to being triple board-certified in...
Mainstay Medical has announced the completion of enrolment in its RESTORE randomised clinical study of ReActiv8 for the treatment of intractable chronic low back pain. The study is designed to provide a direct comparison to optimised medical management for...
A novel brain stimulation technique called high-definition transcranial infraslow pink noise stimulation (HD-tIPNS) was recently evaluated in a placebo-controlled pilot study, and found to be both safe and feasible in the treatment of chronic tinnitus. However, writing in the journal...
Brain Navi has announced the demonstration of NaoTrac, a neurosurgical navigation robot, and KrystoLens, a single-use neuro-endoscope, at two upcoming conferences: the Congress of Neurological Surgeons (CNS) annual meeting (9–13 September, Washington DC, USA) and the European Association of Neurosurgical Societies...
Nevro Corporation recently announced the publication of 24-month data from the SENZA painful diabetic neuropathy (PDN) randomised controlled trial (RCT)—the largest RCT to evaluate spinal cord stimulation (SCS) as a PDN treatment, the company claims—in Diabetes Research and Clinical Practice. Published...
Protembis has announced the appointment of J Mocco (Icahn School of Medicine at Mount Sinai, New York, USA) as an independent member of its board of directors. Mocco will offer insights into the strategic direction of the company as well...
The UK’s Medicines and Healthcare products Regulatory Agency (MHRA) has designated three new approved bodies to increase the country’s capacity to certify medical devices. TÜV SÜD, Intertek, and TÜV Rheinland UK join the four current UK approved bodies, almost doubling...
Mahesh Jayaraman, an interventional neuroradiologist at Rhode Island Hospital in Providence, USA—who has led national efforts to improve stroke systems of care in the USA—has been named the 2023 president of the Society of NeuroInterventional Surgery (SNIS), a scientific...
Medtronic has received CE-mark approval for its Inceptiv closed-loop rechargeable spinal cord stimulator in the treatment of chronic pain. Inceptiv is the first Medtronic spinal cord stimulation (SCS) device to offer a closed-loop feature that senses each person's unique biological...
NOTE: This video is ONLY available to watch in selected countries and geographies  Much of the clinical success that can be achieved with aspiration-based mechanical thrombectomy is dependent on the characteristics and features of the specific device being used....
A case series conducted by Courtney Ellerbusch (Centura Home Health, Colorado, USA) on multiple sclerosis (MS) patients has found quantitative improvements in strength, spasticity, and range of motion, over a series of 18 treatments with Neubie direct-current neuromuscular electrical...
A collaborative study published in the journal Brain Stimulation has shown that targeted electrical stimulation in epilepsy patients with traumatic brain injury (TBI) can improve memory—more specifically, the recalling of words—by an average of 19%. Led by Michael Jacob Kahana...
Laurent Pierot’s (Reims University Hospitals, Reims, France) long career in the treatment of intracranial aneurysms predates not only what many consider to be the advent of the interventional neuroradiology (INR) specialty, the ISAT trial, but also the introduction of...
The phenomenon of missing outcome data (MOD) within stroke registries of mechanical thrombectomy cases “is not a rare event and does not occur completely at random”. That is a key concluding message from research carried out and recently published...
Massachusetts patients experiencing stroke could soon have access to refined treatment, triage and transport protocols based on a provision in the US state’s new budget. According to a press release from the Society of NeuroInterventional Surgery (SNIS), the provision...
Nurami Medical, a medical device startup company, has received 510(k) clearance from the US Food and Drug Administration (FDA) for its electrospun nanofibre-based product, ArtiFascia Dura Substitute. US sales of this resorbable dural repair graft will begin in the upcoming...
Hubly Surgical has announced the results from the first peer-reviewed study comparing the safety and efficacy of its recently US Food and Drug Administration (FDA)-cleared portable cranial access drill with smart auto-stop to a well-established, non-portable neurosurgical perforator. The...
Enspire DBS Therapy has announced the publication of the results of the EDEN trial—an early feasibility study led by Cleveland Clinic (Cleveland, USA) researchers assessing electrical stimulation of the dentate nucleus for upper-extremity hemiparesis due to ischaemic stroke—in Nature Medicine. The EDEN...
BlueWind Medical has announced that the US Food and Drug Administration (FDA) has granted a de novo marketing request for the Revi system—a “transformative” tibial neuromodulation therapy for the treatment of the symptoms of urgency incontinence alone or in...
Kandu Health has announced preliminary outcomes from the first 40 stroke survivors served by its novel stroke recovery programme, which intends to support stroke patients returning to community settings after hospital discharge. Preliminary data from the first 40 stroke survivors...
A new study led by researchers from the University of Chicago Medicine (Chicago, USA) has revealed that nearly 75% of acute stroke patients wait more than two hours to be transferred to a comprehensive stroke centre (CSC)—a treatment delay that creates...
Hyperfine has announced completed enrolment for HOPE PMR—a multicentre, observational pilot study assessing portable magnetic resonance imaging (MRI) in children with neurological injury, using hydrocephalus as an index condition. With the aim of exploring a safer, more accessible solution for...
Flow Neuroscience, the creator of the Flow transcranial direct current stimulation (tDCS) headset for at-home, non-invasive brain stimulation to treat depression, has announced the results of its US Food and Drug Administration (FDA) pivotal clinical trial. The results show...
Imperative Care has announced a new organisational structure designed to accelerate the company’s growth across its businesses. As per an Imperative press release, this new business architecture connects a “continuum of stroke and vascular care” for patients, from onset...
NeuroNews’ 10 most popular stories from July reveal a huge amount of interest in the treatment of stroke patients with medium vessel occlusions (MeVOs)—with the role of mechanical thrombectomy being examined via expert opinion and published research alike. Key...
Saluda Medical has announced the publication of new health economic data in the Clinical Journal of Pain that provides “the strongest ever economic case” for the use of its Evoke closed-loop spinal cord stimulation (SCS) with physiologic SmartLoop technology over open-loop SCS therapy,...
More stroke patients are benefitting from life-changing treatment thanks to Brainomix's e-Stroke artificial intelligence (AI) platform, according to a recent report from the Oxford Academic Health Science Network (AHSN). Brainomix's e-Stroke imaging technology uses AI to automatically process computed tomography...
A study presented at last week’s Society of NeuroInterventional Surgery (SNIS) annual meeting (31 July–4 August 2023, San Diego, USA) noted that mechanical thrombectomy—in addition to its usage in adults with large vessel occlusion (LVO) stroke—is also safe and...
Using a ‘care hotel’ model, which discharges patients to a specialty hospital hotel after smaller surgeries, can lower costs and shorten patients’ time in the hospital following some elective neuroendovascular interventions. That is according to a study presented recently...
Enspire DBS Therapy recently announced that it has raised US$17.6 million of committed capital in a Series B financing led by existing investor Cleveland Clinic Innovations. Also participating in the round were JobsOhio Growth Capital Fund and an undisclosed investor. The company...
Anuncia Medical has announced the successful first implant of the company's US Food and Drug Administration (FDA)-cleared ReFlow mini flusher device. Performed on by neurosurgeon Samuel Cheshier (Intermountain Primary Children's Hospital, Salt Lake City, USA), the patient previously required at least 11...
Imperative Care has announced late-breaking data from the Neurovascular Quality Initiative-Quality Outcome Database (NVQI-QOD) evaluating its Zoom stroke solution, which were presented at the Society of NeuroInterventional Surgery (SNIS) annual meeting (31 July–4 August 2023, San Diego, USA) by...
Kernel has unveiled its Flow2 system, which the company claims will give researchers and clinicians “unprecedented access” to robust, functional magnetic resonance imaging (fMRI)-like neuroimaging in a quick and user-friendly headset—making precision neuromedicine “more accessible than ever before”. Flow2 incorporates...
During a late-breaking abstract session at this year’s Society of NeuroInterventional Surgery (SNIS) annual meeting (31 July–4 August, San Diego, USA), researchers discussed a smartphone application that can reliably, autonomously recognise patients’ physical signs of stroke thanks to the...
Contrary to the results of a seminal study in the field, a recent analysis presented at the Society of NeuroInterventional Surgery (SNIS) annual meeting (31 July–4 August, San Diego, USA) indicates that surgical approaches—including embolisation, microsurgery and radiosurgery—for treating...
Viz.ai has announced the presentation of three new abstracts that demonstrate the real-world impact of the Viz neuro suite at this week’s Society of NeuroInterventional Surgery (SNIS) annual meeting (31 July–4 August, San Diego, USA). These independent studies demonstrate...
A study presented yesterday at the Society of NeuroInterventional Surgery (SNIS) annual meeting (31 July–4 August, San Diego, USA) indicates that it may be possible to use a less invasive technique to identify the gene mutations responsible for some...
EOSolutions has announced the US Food and Drug Administration (FDA) 510(k) submission, through a design consulting firm, of the Thinline 8Fr sheath—a vascular access solution designed to complement the “remarkable features” of the company’s Dr Banner balloon guide catheter (BGC). Together,...
Imperative Care has announced multiple new pieces of data from studies evaluating its Zoom stroke solution, presented at the ongoing Society of NeuroInterventional Surgery (SNIS) annual meeting (31 July–4 August, San Diego, USA). “We are pleased to see the results...
Aidoc has announced the launch of its “revolutionary” Full Brain solution, which the company claims will significantly expand the anatomy analysed by artificial intelligence (AI) to identify suspected strokes, allowing for identification and care coordination of patients with medium...
Research presented at the ongoing Society of NeuroInterventional Surgery (SNIS) annual meeting (31 July–4 August, San Diego, USA) has shown that different types of stent-retriever tips may result in improved patient outcomes when performing a mechanical thrombectomy to treat...
Microvention, a wholly owned subsidiary of Terumo Corporation, has announced the publication of five-year follow-up data from the WEB-IT trial and the addition of two sizes to its Woven EndoBridge (WEB) aneurysm embolisation system. With these now-published five-year clinical trial data,...
A study presented on the first day of the 2023 Society of NeuroInterventional Surgery (SNIS) annual meeting (31 July–4 August, San Diego, USA) has found that US rates of endovascular stroke thrombectomy are projected to increase “dramatically” based on...
This advertorial, sponsored by Siemens Healthineers, is intended for US readers only. A neurosurgical clinic in Raleigh, USA recently opened an office-based lab (OBL)—specifically, the country’s first office-based endovascular neuro practice supported by a fixed biplane angiography system from Siemens...
Administering antiplatelet medication within 24 hours of a mechanical thrombectomy procedure may help stroke patients recover more successfully and prevent high-risk individuals from experiencing additional strokes, according to a study presented yesterday at the Society of NeuroInterventional Surgery (SNIS)...
Route 92 Medical has today announced the publication of a retrospective, first-in-human study featuring its FreeClimb 70 reperfusion system in the journal Interventional Neuroradiology. The study, conducted across five US centres and one international site, reports “impressive” M1 first-pass...
A novel approach to vagus nerve stimulation (VNS) may enable successful post-stroke recovery without the need for “invasive and often-uninsured” traditional VNS therapies. A paper published in the journal Neurorehabilitation and Neural Repair by Medical University of South Carolina (MUSC) researchers...
Mainstay Medical recently announced the publication of three-year clinical data from the post-market clinical follow-up (PMCF) study of 33 ReActiv8 patients at five medical centres across the UK. ReActiv8 is an implantable medical device designed to treat adults with...
Anuncia Medical has announced the successful US commercial launch of the ReFlow mini flusher—a second-generation device for the treatment of hydrocephalus. According to a company press release, neurosurgeons in the USA and, soon, internationally will now have a new...
In a guest piece for NeuroNews, Thomas Devlin (Chattanooga, USA) and Michelle Luffey advise the community on how best to navigate the transition from primary stroke centres (PSCs) to comprehensive stroke centres (CSCs) and, in doing so, provide stroke...
Nicolab and Titan Neuroscience Research Australia have announced the formal signing of a Memorandum of Understanding (MOU) between the two organisations. The MOU outlines the establishment of a collaborative partnership aimed at leveraging their respective resources and expertise. This MOU...
Hubly Surgical has successfully closed its Series seed funding round at an oversubscribed US$3 million. As per a company announcement, this investment comes on the heels of a recent US Food and Drug Administration (FDA) clearance for the Hubly Drill—a patented...
Nalu Medical, a company that has miniaturised neurostimulation implants for the management of chronic intractable pain for both peripheral nerve stimulation (PNS) and spinal cord stimulation (SCS) indications, presented new data from several studies at the recent American Society...
Imperative Care has announced US Food and Drug Administration (FDA) 510(k) clearance of its Zoom 88 large distal platform (LDP) support, a portfolio expansion of the company’s original Zoom 88 LDP. In a press release, Imperative claims to have pioneered...
RapidAI today announced US$75 million in Series C funding led by Vista Credit Partners, a subsidiary of Vista Equity Partners and strategic financing partner focused on the enterprise software, data and technology markets. A press release details that the funding aims to...
Arsenal Medical has today announced enrolment of the first patient treated with the company’s investigational NeoCast embolic biomaterial for neurovascular conditions. The patient was successfully embolised as part of the NeoCast first-in-human clinical trial—an open-label, multicentre study evaluating the early...
iVascular has announced that the SEMTIC study, evaluating the safety and efficacy of its comprehensive stroke thrombectomy treatment, is one step closer to providing its first outcome data, with more than 50% of patients having now been enrolled. The primary...
When utilised as a first-line technique for medium vessel occlusion (MeVO) stroke, aspiration and stent-retriever thrombectomy have demonstrated “no significant difference” in imaging-related or clinical outcomes. That is according to a multicentre, propensity score-matched analysis including more than 400...
Insightec has announced US Food and Drug Administration (FDA) approval of the five-year study endpoint for what it claims is the largest prospective, long-term follow-up study of unilateral magnetic resonance-guided focused ultrasound (MRgFUS) surgery, or ‘thalamotomy’, for essential tremor...
Magnus Medical has announced that the first participants have been treated in the Open Label Optimisation (OLO) clinical trial evaluating the effectiveness of the company’s neuromodulation system with SAINT technology for the treatment of major depressive disorder (MDD). “SAINT therapy...
Experts in Germany are working on an ‘intelligent suit’ with which they hope to significantly improve rehabilitation after a serious spinal cord injury. This artificial intelligence (AI)-supported solution will be developed over the next three years by researchers from...
Researchers in Germany have developed a new deep learning model for detecting stroke lesions, claiming that—by leveraging rich geometric information to segment brain stroke lesion images—the proposed approach may be able to outperform other, more widely used neural network...
Neurolief has announced positive results from a planned interim analysis of the ongoing, randomised controlled MOOD pivotal trial, which is studying Relivion DP—a novel neuromodulation therapy for the treatment of major depressive disorder (MDD). At a meeting of the study's...
Rapid Medical has announced new clinical data demonstrating the “significant advantages” of its novel Comaneci embolisation assist device over established techniques to treat ruptured wide-neck intracranial aneurysms. A recent meta-analysis published in World Neurosurgery found that Comaneci is associated with...
The concluding findings of a systematic review and meta-analysis published in the journal Neurosurgery indicate that flow-diverter performance in posterior communicating artery (PComA) aneurysms is “comparable” to the outcomes observed in other supraclinoid aneurysm subtypes. Authors Santiago Ortega-Gutierrez (University of...
Cognito Therapeutics has announced “robust, lobe-specific” changes in white matter volume and myelination in Alzheimer’s disease patients following six months of non-invasive gamma stimulation therapy using its at-home wearable device. The company presented new imaging data at the 2023 Alzheimer’s...
The neuromodulation space has proliferated significantly over the past few years, and one area in which this is most notable is with the expansion of spinal cord stimulation (SCS)—not only in terms of technological advancements, but also regarding the...
Royal Philips has today announced enrolment of the first patients in both the USA and France into the large-scale WE-TRUST study—a multicentre, prospective randomised controlled trial assessing whether a direct-to-angio-suite (DTAS) workflow improves outcomes for early time-window stroke patients...
Despite having worse stroke symptoms and living within comparable distances to comprehensive stroke centres (CSCs), women with large vessel occlusion (LVO) acute ischaemic stroke are less likely to be routed to these types of centres compared to men, according...
The two prevailing techniques used during surgical treatments of traumatic acute subdural haematomas (SDHs)—craniotomy and decompressive craniectomy—have demonstrated broadly similar efficacy outcomes in a randomised controlled trial (RCT). However, reporting their findings in the New England Journal of Medicine...
Evren Technologies has announced the launch of its Phoenix 100 system, a “state-of-the-art” transcutaneous auricular vagus nerve stimulator (taVNS) research tool. The Phoenix 100 system is intended to solve longstanding challenges faced by researchers in the realm of VNS, as—according to a...
A US centre has achieved a steep drop in infection rates among its neurosurgery patients over a two-year period thanks to the implementation of a multidisciplinary quality and process improvement initiative—as per a recent presentation at the Association for...
Stryker has commercially launched its Q guidance system with cranial guidance software to provide surgeons with an image-based planning and intraoperative guidance system that assists in positioning instruments and identifying patient anatomy during cranial surgery. The software can be used...
Engineers at Rice University (Houston, USA) have created nanoelectrodes that are minimally invasive and exceptionally flexible—and, as such, have the potential to function as an implanted platform, enabling long-term, high-resolution neurostimulation therapy. As per a statement from Rice University, traditional,...
Hyperfine, the company that created the Swoop system—which it claims is the world’s first US Food and Drug Administration (FDA)-cleared portable magnetic resonance (MR) brain imaging system—has today announced the commencement of the ACTION PMR study. To support its acute stroke care...
With multiple large clinical trials currently underway to assess thrombectomy treatments in patients with medium vessel occlusion (MeVO) stroke, Johanna Ospel (Calgary, Canada) takes a look at the possibility of endovascular therapy (EVT) becoming the standard of care for...
ZAP Surgical Systems has announced that the company has received National Medical Products Administration (NMPA) approval in China for its ZAP-X gyroscopic radiosurgery platform. ZAP-X was previously granted NMPA’s Chinese Medical Device Evaluation (CMDE) green pathway, an accelerated path for...
Zeta Surgical has successfully treated its first patient using the Zeta cranial navigation system as part of a first-in-human trial at the National Neuroscience Institute (NNI) in Singapore. The clinical trial at NNI aims to evaluate the safety, efficacy and feasibility of...
Append Medical has raised US$4.35 million as part of an extended series A round, which will be used to support the company's first-in-human trials of Appligator. Investors include participants from the first tranche of the series A round, as well as new investors,...
The results of a clinical trial have shown that a drug commonly used for patients with bleeding disorders has the potential to lessen the side-effects of blood-thinning drugs in stroke patients. Researchers from the University of Nottingham (Nottingham, UK) and...
Highly targeted electrical stimulation to the brain has shown promise as a treatment option for acute ischaemic stroke, according to a pilot study led by University of California Los Angeles (UCLA) Health researchers in Los Angeles, USA. The study is the first...
In addition to a number of key study presentations from the European Stroke Organisation Conference (ESOC; 24–26 May, Munich, Germany), NeuroNews’ most popular stories from June include pain physicians’ response to a recent review of spinal cord stimulation (SCS)...
MindRhythm, in partnership with Wayne State University School of Medicine (Detroit, USA), recently announced that the first patient has been enrolled in the pivotal portion of its EPISODE-VS study—which is designed to validate that use of the company’s proprietary...
Researchers at the RIKEN Center for Brain Science (CBS) in Wako, Japan have discovered a set of related mutations that lead to intracranial aneurysms. The mutations all appear to act on the same biological signalling pathway, and—writing in the...
Theranica has announced the results of a study recently published in the journal Headache demonstrating the safety of its Nerivio device—a novel remote electrical neuromodulation (REN) wearable—as a drug-free treatment for pregnant women with migraine. The study found no statistically...
Neuroprotective agents and steerable microcatheter technologies were among a number of potential new interventional neuroradiology (INR) frontiers showcased and discussed at this year’s LINNC Paris Course (5–7 June 2023, Paris, France)—with faculty member Ricardo Hanel (University of Florida, Jacksonville,...
SynerFuse has announced that—for the first time in the world, it claims—a solo spine surgeon has performed the SynerFuse procedure in a two-level spinal fusion patient. Rohan Lall (M Health Fairview, Minneapolis, USA) performed the procedure and implanted a neurostimulator...
Just two months after announcing what it claims is the “world's first positive surgical trial” in haemorrhagic stroke, NICO Corporation is awarding a US$200,000 investigator-initiated study grant with the goal of building on conclusions from the ENRICH study and...
Microvention, a wholly owned subsidiary of Terumo, has announced that the ERIC retrieval device is now commercially available in the USA for ischaemic stroke treatment, having received 510(k) clearance from the US Food and Drug Administration (FDA) on 31 March 2022. "The...
A new study from Keck Medicine at the University of Southern California (USC; Los Angeles, USA) has uncovered “significant racial disparities” in the diagnosis, treatment and outcomes of peripheral artery disease (PAD) among Black and white patients in the USA. “We discovered that Black...
InspireMD today announced that it has completed enrolment of its ongoing C-Guardians US Investigational Device Exemption (IDE) clinical trial, designed to support potential US marketing approval of its CGuard Prime embolic prevention stent (EPS) system. The C-Guardians clinical trial is...
Expert groups from the USA and China have separately introduced new guidelines relating to the management of aneurysmal subarachnoid haemorrhage (aSAH). The updated guidelines—spearheaded by the American Heart Association/American Stroke Association (AHA/ASA)—are intended to provide “patient-centric recommendations for clinicians...
LivaNova has announced that the 150th bipolar depression patient has been randomised in its RECOVER clinical study—a prospective, multicentre, double-blinded randomised controlled trial investigating the safety and effectiveness of the company’s vagus nerve stimulation (VNS) therapy system as an...
j mocco

J Mocco

As president of the Society of NeuroInterventional Surgery (SNIS), endovascular neurosurgeon J Mocco (Icahn School of Medicine at Mount Sinai, New York, USA) has aspired to take the baton from his predecessors and carry forward their work in improving...
Alessandro Gregio (University of Bologna, Bologna, Italy) recently presented midterm results from the Carotid asymptomatic stenosis observational study during the first of two Society of Vascular Surgery-Vascular and Endovascular Surgery Society (SVS-VESS) scientific sessions on the opening day of...
As per a press release from AptaTargets, JAMA Neurology has published positive results from APRIL—a Phase 1b/2a clinical trial evaluating the safety and efficacy of the neuroprotective drug ApTOLL in combination with endovascular therapy (EVT) in patients with acute...
Pain physicians have urged the Cochrane Library to retract and revise a recent review of spinal cord stimulation (SCS) in the treatment of low back pain, citing “striking errors” across the publication’s methodology, executions and conclusions. Writing in the Cochrane...
Sensome and Asahi Intecc have today announced a collaboration to develop the next-generation Clotild smart guidewire, with Asahi Intecc taking on the manufacturing role for this artificial intelligence (AI)-powered device intended for the treatment of acute ischaemic stroke. As a...
Transient ischaemic attacks (TIAs) encountered with incomplete neurovascular imaging in emergency departments (EDs) have been associated with higher odds of subsequent stroke within 90 days, as per a publication in the American Journal of Roentgenology (AJR). “Increased access to urgent neurovascular...
Imperative Care recently announced the appointment of Kirsten Carroll as the new CEO of Kandu Health—a digital health startup with the aim of improving quality of life for people affected by stroke. The company has also announced the successful enrolment...
A prospective study has demonstrated that carotid intervention can improve mood in depressed patients with advanced carotid disease, in addition to enabling cognitive improvements irrespective of baseline depression. These findings were presented at the Vascular Annual Meeting (VAM; 14–17 June,...
A durability study that looks at reintervention risk among patients treated with carotid endarterectomy (CEA) versus carotid artery stenting (CAS) proce­dures established that CEA demonstrated the lowest risk up to six months after sur­gery. A subgroup analysis between stenting...
Findings that consider the incidence of carotid stent fractures and their impact on stent durability were elucidated by Neeta Karani (Bronson Healthcare, Kalamazoo, USA) during a plenary session at this week's Vascular Annual Meeting (VAM; 14–17 June 2023, National...
A study presented recently at the Vascular Annual Meeting (VAM; 14–17 June, National Harbor, USA) has found that the long-term outcomes of transcarotid artery revascularisation (TCAR) are “not significantly affected” by prior head and neck radiation. Owing to substantially...
Earlier this year, researchers debuted single-centre experiences indicating that intravascular lithotripsy (IVL) may be able to expand transcarotid artery revascularisation (TCAR) into patients with traditionally prohibitive calcific disease. With a multicentre case series now further suggesting IVL’s utility, but...
Royal Philips has today announced the results of a health economics analysis published in the Journal of NeuroInterventional Surgery (JNIS) that show an “innovative approach” to the stroke care pathway—referred to as direct-to-angio suite (DTAS)—can reduce costs by an average of €2,848...
A multicentre study presented at the recent European Stroke Organisation Conference (ESOC; 24–26 May, Munich, Germany) has found that vision recovery and an increased likelihood of early neurological improvement are among the potential benefits endovascular therapy (EVT) can offer...
A new study conducted by scientists at Louisiana State University (LSU) Health New Orleans Neuroscience Center of Excellence (New Orleans, USA) reports that the additive neuroprotection of a combination of two omega-3 fatty acid-derived signalling molecules is more effective...
By identifying plasma proteomic determinants of incident cardioembolic and non-cardioembolic ischaemic stroke, researchers in the USA have found a novel protein believed to be associated with stroke risk in patients with left atrial dysfunction. Detailing findings from the Cardiovascular Health...
Imperative Care has announced the publication of early clinical data in the Journal of NeuroInterventional Surgery (JNIS) from a single-centre evaluation of the Zoom RDL radial access system. This independent, retrospective evaluation of Zoom RDL in 29 patients—who underwent neurointerventional procedures from...
Precision Neuroscience Corporation has announced that the first in-human procedures in a pilot clinical study of its neural implant system have been successfully completed. In partnership with West Virginia University Rockefeller Neuroscience Institute (WVU RNI; Morgantown, USA), this study...
Presenting first-time data from large multicentre European studies at this year's Leipzig Interventional Course (LINC 2023; 6–9 June, Leipzig, Germany), Arne Schwindt (St Franziskus Hospital Münster, Münster, Germany) and Ralf Langhoff (Sankt Gertrauden Hospital, Berlin, Germany) delivered results that...
The US Food and Drug Administration (FDA) has released draft guidance with updated recommendations for good clinical practices (GCPs) aimed at modernising the design and conduct of clinical trials. In a statement, the regulator said that the updates are intended...
Neuralace Medical has announced the upcoming clinical study presentation of the SEAT randomised controlled trial (RCT), which is assessing the safety and efficacy of its Axon therapy, at the American Society of Pain and Neuroscience (ASPN) conference (13–16 July, Miami, USA). Leonardo...
While the exact location of atherosclerotic plaque ruptures—a common cause of myocardial infarction (MI) and stroke—has previously been unknown, researchers at Lund University (Lund, Sweden) have now managed to successfully map this phenomenon. In addition, the team has identified...
While a handful of our highlights from the European Stroke Organisation Conference (ESOC; 24–26 May, Munich, Germany) unsurprisingly feature in NeuroNews’ most-read stories through the month, key industry updates and a closer look at how ChatGPT (Open AI) may...
The MAGNA meta-analysis of individual patient data (IPD) has provided “strong, generalisable evidence” on the clinically meaningful benefits of endovascular therapy (EVT) in ischaemic stroke patients with a large-core infarct volume. Late-breaking findings from MAGNA were presented by Amrou...
At a time when many of Europe’s medical technology markets are effectively going backwards due to complications created by the EU Medical Device Regulation (MDR), corresponding sectors in the USA are receiving an inevitable boost. Alongside the US Food...
Anuncia Medical has announced that an article highlighting its US Food and Drug Administration (FDA)-cleared and CE-marked ReFlow ventricular system (Gen 1) with hydrocephalus shunts in patients suffering from chronic shunt occlusions has been published in Pediatric Neurosurgery. Two years prior...
Nalu Medical has announced the first patient enrolment in the COMFORT-2 randomised controlled trial (RCT), which will assess the company’s peripheral nerve stimulation (PNS) technologies. Together with COMFORT-1, COMFORT-2 is designed to enrol the largest cohort of RCT subjects...
New data from the VECTOR randomised controlled trial—presented at the European Stroke Organisation Conference (ESOC; 24–26 May, Munich, Germany)—have indicated that a mechanical thrombectomy in which a stent retriever is deployed alongside contact aspiration, a 'combined technique', is not...
Highlights: Positive results with the Woven EndoBridge (WEB; Microvention/Terumo Corporation) device—presented for the first time at the LINNC Americas Seminar (16–17 March, Miami, USA)—indicate its utility across a range of intracranial aneurysm types Our very own editor-in-chief, Philip M...
Highlights: Positive results with the Woven EndoBridge (WEB; Microvention/Terumo Corporation) device—presented for the first time at the LINNC Americas Seminar (16–17 March, Miami, USA)—indicate its utility across a range of intracranial aneurysm types Our very own editor-in-chief, Philip M...
The results of the TESLA trial were recently presented at the European Stroke Organisation Conference (ESOC; 24–26 May, Munich, Germany), demonstrating a “strong suggestion” across several domains that endovascular therapy (EVT) can provide benefits over best medical management (BMM)...
Penumbra has announced the US Food and Drug Administration (FDA) clearance and launch of Lightning Bolt 7, which the company claims is the most advanced and powerful arterial thrombectomy system on the market. Lightning Bolt 7 introduces a new method...
Adept Medical has announced the launch of the Head Immobiliser—a radiolucent support for a range of interventional radiology (IR) and neuroradiology procedures. Now commercially available, the positioning device can help mitigate the costs of retakes, from reducing the amount...
Following the presentation of new trials assessing intracranial haemorrhage (ICH) treatment approaches, INTERACT3 and ENRICH, Craig Anderson (The George Institute for Global Health, Sydney, Australia)—who delivered first-time data from the former of the two studies—posited that, “maybe, the time...
Stryker has announced that Early Product Surveillance (EPS) cases utilising its Q guidance system with cranial guidance software are underway. The technology provides surgeons with image-based planning and an intraoperative guidance system designed to support cranial surgeries, a company press...
A collaboration analysing several major clinical trials has found that endovascular therapy (EVT) plus intravenous thrombolysis (IVT) is likely to be superior to EVT alone—also known as direct EVT—in the majority of ischaemic stroke patients, but that one of...
Nicolab has been awarded a prestigious three-year contract to supply stroke workflow software and advanced artificial intelligence (AI) diagnostics for the Victorian Stroke Telemedicine (VST) service in Viewbank, Australia. The VST service—a virtual platform that connects healthcare professionals across multiple...
EOSolutions Corporation has announced the introduction of the Dr Banner balloon guide catheter (BGC), which boasts “unmatched features” for neurovascular procedures. As per a company press release, the device was developed in collaboration with InNeuroCo, and sets “new benchmarks”...
Supplying healthcare providers with performance feedback can significantly reduce the time between an ischaemic stroke patient arriving at a hospital and them subsequently receiving endovascular therapy (EVT), according to the findings of a clinical trial presented at last week’s...
Onward Medical has announced a recent publication in Nature showing that a wireless brain-computer interface (BCI) can use patients’ thoughts to modulate ARC therapy. Researchers reported that, when paired with the company’s ARC therapy, an implanted BCI allowed an...
Positive results from a clinical trial involving a novel therapeutic procedure known as sonolysis—deployed during a carotid endarterectomy (CEA)—were presented at the recent European Stroke Organisation Conference (ESOC; 24–26 May, Munich, Germany). “The randomised clinical trial confirmed the results of...
NeuroOne Medical Technologies has announced the first clinical case using the Evo stereoelectroencephalography (sEEG) electrode in robotic neurosurgery. Performed by William Bingaman at Cleveland Clinic in Cleveland, USA, the procedure was the first to utilise NeuroOne’s Evo sEEG electrode—exclusively marketed in the...
A retrospective study from China has concluded that the Pipeline Flex embolisation device (Medtronic) is safe and effective in the treatment of complex intracranial aneurysms. Reporting their results in Nature: Scientific Reports, Shun-Qiang Chen (Henan Provincial People's Hospital, Zhengzhou,...
Artiria Medical, a Swiss neurovascular company, has announced that its real-time, deflectable guidewire has been granted 510(k) clearance by the US Food and Drug Administration (FDA). This milestone opens a “new pathway” to a “more advanced and effective approach”...
Interim results from the ECST-2 randomised controlled trial (RCT) have shown no evidence that carotid stenosis patients with a low-to-intermediate stroke risk, treated with optimised medical therapy, will benefit from additional carotid revascularisation via carotid endarterectomy (CEA) or carotid...
Results from the TIMELESS trial represent “fantastic news” on the safety of intravenous tenecteplase in selected late-window stroke patients, despite the drug failing to meet its prespecified primary and secondary efficacy endpoints. That is according to Gregory Albers (Stanford...
While patients treated via a structured ambulatory post-stroke care programme (SANO) in a recent cluster-randomised study experienced better control of their cardiovascular risk factors compared to a control group, this did not translate into any significant reduction in recurrent...
In an attempt to promote more consistent and higher quality research in the field of small vessel disease (SVD), international experts have published the second iteration of the Standards for Reporting Vascular Changes on Neuroimaging (STRIVE-2)—an update to the...
As per results from the RESIST study, remote ischaemic conditioning (RIC)—while not being associated with any major safety issues—has failed to improve functional outcomes in patients with acute ischaemic stroke. These findings were presented today at the European Stroke Organisation...
An international clinical trial presented today at the European Stroke Organisation Conference (ESOC; 24–26 May, Munich, Germany) has demonstrated that—in people with ischaemic stroke and atrial fibrillation—anticoagulation can safely be started earlier than current guidelines recommend. "Our study finally brings...
A team of researchers from Denmark have developed a new artificial intelligence (AI) framework to address the number of strokes that go unrecognised by human emergency call handlers. The framework outperformed emergency call handlers in recognising stroke for both...
The Woven EndoBridge (WEB) 17 device (Microvention/Terumo Corporation) has demonstrated positive efficacy and safety outcomes in the prospective, multicentre CLEVER study, indicating its utility for intrasaccular embolisation across ruptured and unruptured intracranial aneurysms. Twelve-month results from the study were...
A new randomised controlled trial (RCT)—the “largest ever” of its kind in the major depressive disorder (MDD) space—will attempt to provide a “thorough understanding” of how treatment-resistant patients respond to vagus nerve stimulation (VNS) therapy. Details of the RECOVER trial...
Both open and endovascular surgical approaches are likely to produce improved outcomes compared to ligation in the treatment of ruptured extracranial carotid artery aneurysms. This was the salient point delivered by Maarit Venermo (Helsinki University Hospital, Helsinki, Finland) at the...
An analysis published in the Journal of Neurosurgery, which assessed ChatGPT’s (OpenAI) performance on a surrogate for neurosurgical board-style questions, has found that the natural language processing (NLP) algorithm was able to significantly outperform medical students and was only...
Abbott has announced that the US Food and Drug Administration (FDA) has approved its spinal cord stimulation (SCS) devices for the treatment of chronic back pain in people who have not had or are not eligible to receive back...
‘Upstream’ causes of health inequities related to stroke—such as structural racism and conditions of the places where people live, learn, work and play—have not been studied well, according to a recent American Heart Association (AHA) scientific statement. The statement,...
RapidAI announced recently that its combined haemorrhagic solution—Rapid ICH (intracranial haemorrhage) and Rapid Hyperdensity—has been selected as the “Best New Imaging Solution” in the seventh annual MedTech Breakthrough Awards, which attracted more than 4,000 nominations from over 17 countries this...
Magnus Medical has shared promising results from a clinical trial published in the Proceedings of the National Academy of Sciences indicating that treatment with SAINT neuromodulation reverses abnormal brain signalling by changing the direction of brain signal flow in people with...
A nationwide cohort study of over 9,000 patients shows that the “controversial” practice of arteriotomy closure for carotid endarterectomy (CEA) is associated with an increased risk of ipsilateral stroke and “should be avoided”. Instead, authors Magnus Jonsson (Karolinska University...
As per a recently published retrospective chart review, the removal of sacral neuromodulation (SNM) devices in the office setting, under local anaesthesia, is a safe, well-tolerated and effective procedure. Reporting their findings in the journal Urology, Sarah Martin and Howard...
Carthera has announced the publication in The Lancet Oncology of results from a Phase 1 clinical trial carried out by scientists at Northwestern University Feinberg School of Medicine (Chicago, USA). In the trial, they used the SonoCloud-9 implantable ultrasound...
Endovascular therapy (EVT) has been deemed safe and effective in patients with ischaemic stroke caused by an anterior circulation large-vessel occlusion (LVO) who present 6–24 hours from onset, or last seen well, who were selected on the basis of...
Abbott has announced that the US Food and Drug Administration (FDA) has approved expanded magnetic resonance imaging (MRI) labelling for its Eterna spinal cord stimulation (SCS) system to include new leads that are MR conditional—meaning people with chronic pain...
Earlier this week, the European Academy of Neurology (EAN) announced the launch of the Brain Health Mission, a collaborative initiative that aims to address the global crisis of brain disorders and present solutions. The mission brings together governments, healthcare providers,...
“Overall, we just need better tools” was one of the salient points delivered by Jane Khalife (Cooper University Health Care, Camden, USA) in a talk at the LINNC Americas Seminar (16–17 March, Miami, USA) focusing on stroke cases with...
Hubly Surgical has received 510(k) clearance from the US Food and Drug Administration (FDA) to market its Hubly Drill, which the company describes as an innovative medical technology developed with the goal of making burr-hole procedures safer and more efficient in...
The Get Ahead of Stroke campaign is launching Survive Stroke Week from 15–21 May—an observance aimed at increasing awareness of stroke symptoms and the importance of calling 911 right away. The longer a stroke patient’s treatment is delayed, the greater...
This advertorial is sponsored by CERENOVUS. The EMBOTRAP® family of revascularisation devices (CERENOVUS) is innovative within the stent retriever space due to its differentiated design based on a wealth of clot-science research. As a physician currently using EMBOTRAP in mechanical...
Cerevasc has announced that data on its minimally invasive central nervous system (CNS) delivery system will be presented for the first time at the American Society of Gene and Cell Therapy annual meeting (16–20 May 2023, Los Angeles, USA). The...
Brian Fiani (Livonia, USA) and Ryan Jarrah (Rochester, USA) take a look at the neurosurgical implications of one of the hottest topics permeating not only the medical industry, but virtually all of society, right now—the natural language processing (NLP)...
A systematic review and analysis published in the journal Interventional Neuroradiology has examined how far along “the right path” management paradigms for persistent primitive trigeminal artery (PPTA) aneurysms currently are—ultimately concluding that, while endovascular techniques in this area are successful, “meticulous”...
ConcertAI's TeraRecon has announced the release of Neuro Suite, its artificial intelligence (AI)-driven clinical suite, which the company claims is purpose-built for disease triage, differential diagnostic insights, and care activation in many neurological disease states—such as neuro-oncology, dementia, multiple...
MIVI Neuroscience has announced that it has completed enrolment in the EVAQ clinical trial to assess the safety and effectiveness of the Q revascularisation system for the treatment of acute ischaemic stroke. The EVAQ trial has enrolled 121 patients at 17...
“The time has definitely come to look at the evidence, and redo these studies,” posited Alun Davies (Imperial College London, London, UK), putting forward his argument that the NASCET and ECST clinical trials “need to be reconducted” at this...
The Heart and Stroke Foundation, Brain Canada, and the Canadian Stroke Consortium, have announced the recipients of the 2022 Stroke Clinical Research Catalyst grants. The purpose of this programme, as per a joint press release, is to increase the capacity for clinical stroke...
A number of potentially contentious issues caught the eye of our readers in April—including how best to define 'success' in stroke thrombectomy; efforts to expand the range of specialties capable of performing these procedures; and question marks over the...
NeuroOne Medical Technologies has announced the commercial launch of the Evo stereoelectroencephalography (sEEG) electrode product line in the USA. Zimmer Biomet holds exclusive worldwide distribution rights to NeuroOne’s Evo Cortical and sEEG product lines, and the Evo product line is expected...
Researchers at the Feinstein Institutes for Medical Research (Manhasset, USA) have received a US$3.4 million grant from Wellcome to study repetitive transcranial magnetic stimulation (rTMS) and its effects—potentially opening the door for a new, non-pharmacological way to treat major mental health disorders like schizophrenia...
Stryker announced today that it has completed the acquisition of Cerus Endovascular—a medical device company engaged in the design and development of neurointerventional devices for the treatment of intracranial aneurysms. Cerus’ CE-marked products, including the Contour neurovascular system and the...
New research has indicated that Mexican Americans have worse outcomes after a stroke than non-Hispanic white Americans. A recent study, which looked at whether the language Mexican American people speak is linked to how well they recover after a stroke,...
Cerenovus has announced that the new Cerepak detachable coils are now commercially available in the USA, and that the first patient cases have been performed. Cerepak is the latest innovation to join the company’s haemorrhagic stroke portfolio. The Cerepak detachable...
More than half of all stroke survivors may develop cognitive impairment within a year after their stroke, and one in three are at risk for developing dementia within five years. That is according to a new American Heart Association (AHA) scientific statement...
Having taken place via a virtual format in 2021, and as a hybrid meeting last year, the 2023 European Stroke Organisation Conference (ESOC; 24–26 May, Munich, Germany) is set to return to a more traditional, fully on-site setup. Robin...
SynerFuse has announced that Michael Park (University of Minnesota, Minneapolis, USA)—principal investigator for the company’s investigational device exemption (IDE) proof-of-concept study—presented data from the study’s first eight patients at the 10th annual Minnesota Neuromodulation Symposium (20–21 April, Minneapolis, USA). "This presentation showcased the...
A debate between two prominent carotid interventionists—Peter Schneider (University of California San Francisco, San Francisco, USA) and Domenico Valenti (King's College London, London, UK)—on the Wednesday of the Charing Cross (CX) symposium (25–27 April 2023, London, UK) revealed that...
Penumbra recently announced the launch of the latest addition to its RED family of catheter devices for mechanical thrombectomy, the RED 43 reperfusion catheter. According to the company, this device is intended to take distal aspiration “to the next level”...
NICO Corporation has announced initial positive results from the completed ENRICH trial at the 2023 American Association of Neurological Surgeons (AANS) annual scientific meeting (21–24 April, Los Angeles, USA). ENRICH was designed to evaluate the safety, efficacy, and economic outcomes...
Route 92 Medical has today announced receipt of 510(k) clearance from the US Food and Drug Administration (FDA) for its FreeClimb 70 reperfusion system, which