Zeta Surgical announces successful first treatment in neurosurgical navigation study


Zeta Surgical has successfully treated its first patient using the Zeta cranial navigation system as part of a first-in-human trial at the National Neuroscience Institute (NNI) in Singapore.

The clinical trial at NNI aims to evaluate the safety, efficacy and feasibility of the Zeta cranial navigation system for pin-less bedside ventriculostomy procedures. The trial is being led by Min Wei Chen (NNI, Singapore), and conducted at Singapore General Hospital and Tan Tock Seng Hospital (both Singapore).

“I am very impressed with the underlying technology and its accuracy,” said Chen. “We are very excited to be the first institution to run this trial on human patients and to have successfully onboarded our first participant with promising early results. We are looking forward to the rest of the trial.”

As per a company press release, Zeta Surgical’s navigation and robotics platform leverages cutting-edge computer vision and artificial intelligence (AI) to enable image guidance directly at the point-of-care—creating new possibilities in fields like emergency care, interventional medicine, and drug delivery.

William Gormley, chief medical officer of Zeta Surgical, added: “Placing a navigated bedside ventricular catheter in a mobile, non-cranially pinned patient is truly a landmark accomplishment. It brings the extraordinary precision found in the neurosurgical operating room of select institutions in the world to all patients, irrespective of if they are in the emergency room, the intensive care unit, or the operating room. It is truly an accomplishment that democratises medicine and will make an enormous difference across a broad range of procedures.”

Raahil Sha, co-founder and chief technology officer of Zeta Surgical, stated: “This trial marks our first step towards making surgical guidance truly accessible across neurosurgery and neuroscience. We are thrilled to be partnering with NNI in our mission to make surgeries more precise, safe and effective.”


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