NeuroNews’ top 10 most popular stories of March 2024

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Major pieces of industry news from a number of innovators in the neurovascular space populate NeuroNews’ top 10 articles of last month—including NeuroOne, Artiria, Arissa and Nanoflex Robotics. Data indicating the more long-term benefits of thrombectomy in patients with large-core infarct volumes, and a meta-analysis evaluating the utility of venous sinus stenting (VSS) for the treatment of idiopathic intracranial hypertension (IIH), are also among those stories that drew the most readers throughout March.

1. One-year TESLA and SELECT2 data favour thrombectomy in large-core stroke patients

One-year follow-up data from two randomised controlled trials (RCTs) evaluating mechanical thrombectomy in patients with ischaemic strokes caused by large-core infarct volumes have demonstrated the more long-term clinical benefits of the procedure—when coupled with standard medical management.

2. NeuroOne initiates limited commercial launch of OneRF ablation system

NeuroOne Medical Technologies has announced that it has initiated a limited commercial launch of its OneRF ablation system, which has US Food and Drug Administration (FDA) 510(k) clearance for creation of radiofrequency lesions in nervous tissue for functional neurosurgical procedures.

3. Nalu Medical closes US$85 million Series E financing round

Nalu Medical has announced the closing of an incremental US$20 million in equity financing from new investor B Capital, bringing its total Series E round of equity investment to US$85 million. According to a press release, this funding will be used to support the expansion of the company’s Nalu neurostimulation system—a minimally invasive, non-pharmacologic solution intended to treat chronic neuropathic pain.

4. Artiria secures funding to support completion of stroke studies in Europe and USA

Artiria Medical has announced the successful closing of a Series A2 round worth US$6 million and the securing of a US$600,000 Fit Tech Growth loan.

5. No-reflow in clinical studies: Causes, rates and implications for patient outcomes

In a guest article for NeuroNews, Adnan Mujanovic (Bern, Switzerland) discusses a relatively unknown but potentially significant factor in stroke patients experiencing poor clinical outcomes following a successful endovascular therapy (EVT) procedure—the ‘no-reflow’ phenomenon.

6. Medtronic files complaint against Axonics to stop “unauthorised use” of neuromodulation innovations

Medtronic recently announced that it has filed a complaint with the US International Trade Commission (ITC), along with a parallel action in US District Court for the District of Delaware, to block Axonics from “improperly importing and selling products” that infringe two Medtronic patents related to the magnetic resonance imaging (MRI) compatibility of implantable medical devices.

7. Arissa reports initial six-month radiographic follow-up from Syntra FIH study

Arissa Medical has announced six-month digital subtraction angiography (DSA) follow-up of the first cohort of patients in its Syntra first-in-human (FIH) study—an early feasibility study evaluating the safety and efficacy of the company’s Syntra device for the treatment of wide-necked sidewall and wide-necked bifurcation cerebral aneurysms.

8. Meta-analysis deems VSS a safe and effective option in selected IIH patients

A meta-analysis published recently in the Journal of the Neurological Sciences has concluded that VSS appears to be a safe and effective treatment option in certain IIH patients—specifically, those who do not respond to medical therapy or have significant visual symptoms.

9. ISC 2024 examines TCAR ‘explosion’ alongside advances in intensive medical therapy

This year’s International Stroke Conference (ISC; 7–9 February, Phoenix, USA) hosted discussions on the current state of play in carotid stenosis treatment—and, most notably, advances that may erode the dominance of long-established carotid revascularisation procedures in the USA.

10. Nanoflex Robotics installs its first remote-ready robotics system in North America

Switzerland-based startup firm Nanoflex Robotics has announced that it recently installed its first remote-ready robotics system for neurovascular procedures at the Jacobs Institute (Buffalo, USA).


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