Study finds significant cognitive impairment in adult survivors of childhood brain...
Cancer survivors of childhood brain tumours show significant deficits in intelligence, educational achievement and employment, even decades after treatment, an unprecedented study at St Jude Children's Research Hospital has found.
Bioness StimRouter neuromodulation system clinical trial results published
Bioness has announced the successful results from the company's one-year clinical trial of the StimRouter neuromodulation system, published in Neuromodulation.
Proton beam therapy may be as safe as radiotherapy for treatment...
The treatment was shown to have similar survival rates to conventional radiotherapy in a study published in The Lancet Oncology.
Natalizumab tied to rising John Cunningham virus levels in people with...
People taking natalizumab for the treatment of multiple sclerosis may be at a heightened risk of developing of progressive multifocal leukoencephalopathy.
Jan Medical secures US$7.5 million in series C funding from Brainlab
This funding will be used to complete ongoing clinical trials and filing of product de novo with the FDA, as well as funding CE mark registration in the EU, for BrainPulse.
First stroke patient treated with Rapid Medical’s Tigertriever
Using Rapid Medical's proprietary technology, this stent retriever is designed to be fully visible and controllable. The device can be adjusted by physicians to fit the dimensions of blood vessels causing acute ischaemic stroke, and is the first of its kind, according to the company.
Karolinska University Hospital to purchase Elekta’s Leksell Gamma Knife Icon
This intracranial stereotactic radiosurgery system is designed to offer precision radiosurgery to more patients with a wider variety of types and sizes of tumour.
First-line aspiration with Sofia device is “worth a try”
Thomas Liebig reported that a first-line aspiration approach with MicroVention's Sofia device is "worth a try" because it is associated with similar results to first-line aspiration approaches with other dedicated intermediate catheters, and unsuccessful aspiration with Sofia can be "easily converted" into stent retriever-based therapy.
Patient follow-up completed for BlueWind Medical’s Peripheral Neuropathic Pain study
The study evaluates the company's Reprieve wireless neurostimulation device, with a view to CE mark accreditation for multiple clinical indications.
Deep brain stimulation of the fornix (DBSf) shows benefit in the...
The phase 2 study appears to demonstrate acceptable safety and increased glucose metabolism in the treatment of patients with mild Alzheimer's disease.dbsf
NeuroPace RNS system receives ‘Most Promising New Product’ award
The closed-loop responsive neurostimulation system recieved the award at the 2015 Phoenix Medical Device CEO Conference
Seven US medical centres to acquire Elekta’s new Leksell Gamma Knife...
Seven centres are first in USA to order Icon, which features the first integrated stereotactic cone beam CT imaging, online adaptive dose evaluation and planning enabling the most accurate delivery of frameless and frame-based treatments, according to Elekta.
WEB .021″ approved for use in US IDE study
Sequent Medical has announced that the US Food and Drug Administration has approved the inclusion of WEB .021" devices for use in its US Investigational Device Exemption (IDE) clinical study called WEB-IT.
EmboTrap could be a “promising” device for acute ischaemic stroke
One of the newest devices to surface for the treatment of acute ischaemic stroke is the EmboTrap from Neuravi. At the World Live Neurovascular Course (WLNC; 8-10 June, Chicago, USA) Osama Zaidat and Tommy Andersson introduced the device and presented the results of the first 25 cases performed by Andersson and the team at Karolinska in Sweden.
New device is “equivalent to, or better than” known flow diverters...
In the first study to be published reporting on endovascular aneurysm treatment with the p64 flow modulation device (Phenox), Francesco Briganti and colleagues have found that the device provides a safe procedure with no technical complications.
AcuteCare Telemedicine partners with Emory Saint Joseph’s Hospital on Telestroke programme
Emory Saint Joseph's Hospital, Atlanta, USA, is improving treatment for stroke patients with the launch of a Telestroke programme, which allows neurologists to remotely evaluate patients around the clock through real-time conferencing with a Telerobot monitor.
Alzheimer’s disease consists of three distinct subtypes according to UCLA study
The finding could lead to more highly targeted research and, eventually, new treatments for the debilitating neurological disorder, which robs people of their memories.
Researchers find evidence of link between stress and Alzheimer’s disease
The research, conducted on a mouse model and in human cells, found that a stress-coping hormone released by the brain boosts the production of protein fragments.
Alzheimer’s may affect the brain differently in African-Americans than European-Americans
The disease may cause different pathologies in African-Americans than in white Americans of European descent, according to a study published in an online issue of the medical journal of the American Academy of Neurology.
Three European health centres to use Elekta’s Leksell Gamma Knife Icon...
Three medical centres in the United Kingdom and Germany have ordered and are now planning upgrades to Elekta's latest generation stereotactic radiosurgery system for the brain, Leksell Gamma Knife Icon.
Uric acid may lessen women’s disability after stroke
Uric acid-a chemical that at high levels can lead to serious illness-may lessen women's disability after stroke, according to new research in the American Heart Association's journal Stroke.
Southend University Hospital utilises 3D Systems’ simulator for life-saving team training...
Southend University Hospital established an innovative interventional stroke service using the ANGIO Mentor Suite simulator at Anglia Ruskin University.
In-home noninvasive brain stimulator may ease Parkinson’s symptoms
To give Parkinson's patients another in-home option, Johns Hopkins graduate students have invented a headband-shaped device to deliver noninvasive brain stimulation to help reduce the symptoms.
Strokes steal eight years’ worth of brain function, new study suggests
In both black and white patients, having had a stroke meant that their score on a 27-item test of memory and thinking speed had dropped as much as it would have if they had aged 7.9 years overnight.
Data demonstrates efficacy of Brainsway’s Deep TMS for treatment of ADHD...
New data demonstrating the efficacy of Brainsway's Deep TMS for the treatment of ADHD and OCD have been presented at the Society of Biological Psychiatry Annual Scientific Meeting ( 14-16 May, Toronto, Canada).
FDA approves Senza spinal cord stimulation system delivering HF10 therapy
Nevro has announced that it has received approval from the United States Food and Drug Administration (FDA) for its Senza spinal cord stimulation system....
Comprehensive stroke centres may improve bleeding stroke survival
People with haemorrhagic strokes are more likely to survive if they are treated at a comprehensive stroke centre, according to research published in the Journal of the American Heart Association.
Flowonix Medical announces first implants of Prometra II
Flowonix Medical has announced that the first implants of its Prometra II intrathecal infusion pump took place on 5 May, 2015 at St Francis Hospital in Charleston, USA.
First biosynthesised cellulose-based dural replacement for neurosurgery launched
DePuy Synthes CMF has announced the launch of Synthecel Dura Repair, the first commercially available biosynthesised dural replacement derived from cellulose for use in neurosurgery.
Cefaly to present breakthrough data in migraine treatment
On 14 May at a meeting of EUROHEADPAIN Cefaly Technology will present three significant patent pending systems of neuromodulation that are in development
Indications expanded for StealthStation electromagnetic surgical navigation technology
Medtronic plc has announced that it has received clearance from the US Food and Drug Administration (FDA) for expanded indications of specific StealthStation electromagnetic surgical navigation system instruments for paediatric and adult cranial and ENT procedures.
St Jude Medical completes acquisition of Spinal Modulation
Now complete, the acquisition of Spinal Modulation adds DRG stimulation technology to the St Jude Medical chronic pain portfolio.
Clinical trial moves stem cell therapy for ALS patients one step...
Stem cells are a safe therapy for patients with amyotrophic lateral sclerosis (ALS), according to the results of a recently completed phase 1 clinical trial.
Brain imaging can help differentiate between PTSD and traumatic brain injuries
By looking at the brain, scientists believe it is now possible to distinguish between two very different conditions that can have very similar symptoms.
Monteris Medical launches NeuroBlate SideFire Select and FullFire Select reduced diameter...
Monteris Medical has announced the launch of two new reduced diameter mini-probes for its NeuroBlate System, a minimally invasive robotic laser thermotherapy tool.
Codman Neuro launches Enterprise 2 in Europe
The Enterprise 2 system is the latest generation of the company's self-expanding stent and delivery system used to treat wide-necked intracranial aneurysms and to help maintain the position of endovascular coils.
Terrence L Cascino elected president of American Academy of Neurology
The American Academy of Neurology (AAN) has elected Terrence L Cascino, Mayo Clinic of Rochester, USA, as its 34th president.
Boston Scientific announces strategic collaboration with Brainlab
As part of the agreement, Boston Scientific will begin distributing the Brainlab deep brain stimulation surgical planning portfolio with the Boston Scientific Vercise deep brain stimulation system in select countries.
Medtronic announces consent decree with FDA for the SynchroMed drug infusion...
The company's efforts are focused on the implementation of design changes to the SynchroMed drug infusion pump to address issues the company has previously communicated, and on enhancing the Neuromodulation quality system.
New Leksell Gamma Knife to benefit more patients with brain disease
With the introduction of Elekta's new Leksell Gamma Knife Icon, the benefits of precision cranial radiosurgery are now available for more patients with a wider variety of tumour types and sizes.
Long-term exposure to air pollution may pose risk to brain structure,...
A new study led by scientists from Beth Israel Deaconess Medical Center and Boston University School of Medicine, USA, suggests that long-term exposure can cause damage to brain structures and impair cognitive function in middle-aged and older adults.
For lower-grade brain blood vessel malformations, surgery has “excellent clinical outcomes”
Interventional treatments-especially surgery-provide good functional outcomes and a high cure rate for patients with lower-grade arteriovenous malformations of the brain, reports the May issue of Neurosurgery.
Effect of Lemtrada on slowing brain atrophy and MRI lesion activity...
In relapsing remitting multiple sclerosis (RRMS) patients treated with Lemtrada in the phase III pivotal studies, MRI effects observed in the two-year trials were maintained through two additional years in the extension study (years three and four).
Medtronic announces European approval of the first and only full-body MR...
The expanded approval for full-body MRI scans applies to all patients receiving a new system and to an estimated 13,000 people in Europe already receiving Medtronic DBS therapy.
FDA clears MRI-compatible MEMS cannula
The Alcyone MEMS cannula is a dual-lumen, MRI-compatible injection and aspiration cannula for use in the brain.
Drugs stimulate body’s own stem cells to replace the brain cells...
A pair of topical medicines already alleviating skin conditions each may prove to have another, even more compelling use: instructing stem cells in the brain to reverse damage caused by multiple sclerosis.
Clinical phase II study with NeuroSTAT for traumatic brain injury passes...
The study of NeuroVive's drug candidate NeuroSTAT will continue as planned and move on to the next dosage group following endorsement from the independent safety committee.
NurOwn demonstrates a statistically significant effect in ALS patients
BrainStorm Cell Therapeutics presented results from its phase 2a study of NurOwn in amyotrophic lateral sclerosis (ALS) at a poster session at the American Academy of Neurology annual meeting, in Washington, DC, USA.
St Jude Medical announces intent to acquire Spinal Modulation
Following the completion of this acquisition, St Jude Medical will become the only medical device manufacturer to offer radiofrequency ablation (RFA), spinal cord stimulation (SCS) and dorsal root ganglion (DRG) stimulation therapy solutions for the treatment of chronic pain.
Two different carotid artery stenting procedures show little difference in effectiveness
Use of either proximal embolic protection devices or distal filter embolic protection devices during elective carotid artery stenting results in low rates of in-hospital stroke and death, according to a new study.
Evidence builds for endovascular treatment of acute ischaemic stroke
With the publication of two more stroke trials, the evidence in favour of endovascular treatment in patients with acute ischaemic stroke has reached new heights. Data from SWIFT PRIME and REVASCAT add to that of three other trials-MR CLEAN, EXTEND-IA and ESCAPE-that have begun to change the face of ischaemic stroke treatment.
First US commercial procedure with the Enroute transcarotid neuroprotection system
Silk Road Medical has announced the first US commercial procedure using the Enroute transcarotid neuroprotection system was successfully performed at Mills-Peninsula Medical Center in Burlingame, USA by vascular surgeon John E Rosenman.
New research study to demonstrate value of PET scans in Alzheimer’s...
The IDEAS study will assess the impact of brain amyloid PET imaging on a variety of patient outcomes.
Clinical utility of real-time navigated laser therapy for lesion ablation within...
Three prominent neurosurgeons will review their clinical experience using real-time navigated laser therapy for brain lesion ablation within intraoperative MRI suites at the upcoming 83rd American Association of Neurological Surgeons (AANS) Annual Scientific Meeting.
The ALS Association to collaborate with GlaxoSmithKline on new ALS clinical...
The ALS Association, Harvard Stem Cell Institute, and Massachusetts General Hospital Neurological Clinical Research Institute have announced that they are collaborating with GlaxoSmithKline on a clinical trial to evaluate the potential of an anti-epileptic drug in ALS patients.
Women and men have different exclusion criteria for clot-busting stroke drug,...
After analysing stroke treatment records, researchers at Rhode Island Hospital in collaboration with researchers from the University of Cincinnati, both USA, learned that women and men have different reasons for being excluded from receiving the common clot-dissolving drug, recombinant tissue plasminogen activator (rt-PA).
Jan Medical’s Nautilus BrainPulse detected cerebral vasospasm with clinically meaningful accuracy...
A clinical study published in Neurocritical Care demonstrated that Nautilus BrainPulse is a highly sensitive skull accelerometry that can detect cerebral vasospasm "with clinically meaningful accuracy".
Drug restores brain function and memory in early Alzheimer’s disease
A novel therapeutic approach for an existing drug reverses a condition in elderly patients who are at high risk for dementia due to Alzheimer's disease, researchers at Johns Hopkins University found.
Stimwave Technologies announces partnership with Epimed International
The partnership, in addition to co-product development, will support distribution of Stimwave's Wireless Pain Relief technology, which became available in the USA in January 2015.
Researchers build brain-machine interface to control prosthetic hand
New University of Houston research has demonstrated that an amputee can grasp with a bionic hand, powered only by his thoughts.
Stimwave appoints Gabor Racz as chair of Medical Advisory Board
Racz has been honoured with several lifetime achievement awards from societies throughout the world in recognition of contributions that span more than five decades.
AANS, CNS and Joint Cerebrovascular Section endorse interventional thrombectomy in treatment...
The three groups endorse the approach in their article, "MR CLEAN: past the tipping point of clinical equipoise," by Henry H Woo et al, published online, ahead of print, in the Journal of Neurosurgery.
High-frequency surpasses traditional spinal cord stimulation in first controlled trial comparing...
The first-ever randomised, controlled trial to compare spinal cord stimulation technologies found that high-frequency stimulation using 10kHz (HF10) exceeded lower-frequency, traditional stimulation in response rate and pain relief.
Health Canada greenlights IMRIS ceiling-mounted intraoperative CT solution
IMRIS Inc has announced that VISIUS iCT, the first and only ceiling-mounted intraoperative computed tomography scanner, has received Health Canada licensing allowing for sales and marketing in the country.
Use of stent, compared to medications, increases risk of stroke in...
The VISSIT study has shown that among patients with symptomatic intracranial arterial stenosis, the use of a balloon-expandable stent compared with medical therapy (clopidogrel and aspirin) resulted in an increase of stroke or transient ischaemic attack.
Brain tumour cells decimated by mitochondrial “smart bomb”
An experimental drug that attacks brain tumour tissue by crippling the cells' energy source called the mitochondria has passed early tests in animal models and human tissue cultures, say Houston Methodist scientists.
New tinnitus treatment study reduces total symptoms by almost 40%
A year-long study shows that Acoustic CR neuromodulation treatment is effective in reducing tonal tinnitus symptoms such as severity and loudness and annoyance by nearly 40%.
Troops who do not pass the smell test are likely to...
Decreased ability to identify specific odours can predict abnormal neuroimaging results in blast-injured troops, according to a new study by US federal researchers released online in the journal Neurology.
UCSF team finds key to making neurons from stem cells
A research team at UC San Francisco has discovered an RNA molecule called Pnky that can be manipulated to increase the production of neurons from neural stem cells.
More neurosurgeons will be required to handle increased brain bleeds
By 2030, chronic subdural haemorrhage will be the most common adult brain condition requiring neurosurgical intervention in the USA, and hospitals and neurosurgeons may be under-manned to handle the projected onslaught of patients, a new study says.
Is it dementia, or just normal aging? New tool may help...
Researchers at Mayo Clinic developed a new scoring system to help determine which elderly people may be at a higher risk of developing the memory and thinking problems that can lead to dementia.
John Theurer Cancer Center joins study exploring novel delivery of cancer-selective...
In this study, Toca 511 is injected directly into the brain tumour through a stereotactic biopsy needle. Once injected, Toca 511 infects tumour cells, sparing healthy functioning brain cells.
Cover device proves more effective than guide catheter in stroke model
In an in vitro stroke model comparison, the use of the Cover accessory device (Lazarus Effect) in conjunction with a stent retriever resulted in higher successful recanalisation rates, no embolic events and proved to be more effective than the use of a conventional guide catheter or a balloon guide catheter.
Feinstein Institute researcher to receive Potamkin Prize for Alzheimer’s research
The Potamkin Prize honours researchers for their work in helping to advance the understanding of Pick's disease, Alzheimer's disease and related disorders.
New technique could lead to long-lasting localised stimulation of brain tissue...
Researchers at MIT have developed a method to stimulate brain tissue using external magnetic fields and injected magnetic nanoparticles-a technique allowing direct stimulation of neurons, which could be an effective treatment for a variety of neurological diseases, without the need for implants or external connections.
Neuralstem announces topline results of phase II ALS trial
Neuralstem has announced top line data from the phase II trial of NSI-566 spinal cord-derived neural stem cells under development for the treatment of amyotrophic lateral sclerosis (ALS).
Using robots for stroke rehabilitation
Researchers have developed a prototype of a robotic glove which stroke sufferers can use in their own home to support rehabilitation and personal independence in receiving therapies.
electroCore non-invasive vagus nerve stimulation is effective in treating cluster headaches
Seventy-nine per cent of patients who completed the trial (15 out of 19) reported an overall improvement in their condition.
One-third of Americans do not have access to stroke centre within...
Even under optimal conditions, a large proportion of the population would be unable to access a stroke centre within this window, according to a new study.
Mouth guards gather new information that may lead to more accurate...
The mouth guards were able to measure six degrees of freedom, including rotational movement (roll, pitch, and yaw), while current safety standards use three degrees of freedom.
Direct brain neurostimulation for partial onset seizures provides long-term benefit
A study of a direct brain responsive neurostimulator found that responsive direct cortical stimulation reduces seizures and improves quality of life over an average of 5.4 years for for partial onset seizures that cannot be controlled with medication
Next generation Medina coil system shows improvements in early human experience
In early use of the Medina coil system, researchers have found the device to be a next generation coil that combines the familiar procedural safety and technique associated with conventional coils, with improved circumferential aneurysm filling, which, they say, it is thought will lead to improved long-term outcomes.
Findings may help with the management of anticoagulant-related bleeding within the...
Reversal of international normalised ratio below a certain level and systolic blood pressure less than 160mmHg at four hours were associated with lower rates of haemorrhage enlargement in oral anticoagulation-associated intracerebral haemorrhage patients, according to a new study.
Long sleepers may have an increased risk of stroke
A new study has found that people who slept more than eight hours a night were 46% more likely to have a stroke than people who slept six to eight hours a night.
FDA clears Bioness StimRouter neuromodulation system
The StimRouter is a minimally invasive implantable device designed to reduce pain by specifically targeting the affected peripheral nerve.
Medtronic acquires Advanced Uro-Solutions
Advanced Uro-Solutions develops and manufactures the NURO percutaneous tibial nerve stimulation system for patients with overactive bladder and associated symptoms.
Resistance to aspirin tied to more severe strokes
Patients who were aspirin resistant also had larger areas of the brain affected by the stroke, as measured by MRI diffusion weighted imaging.
SANTE study shows DBS therapy for treatment-resistant epilepsy demonstrates significant and...
Medtronic DBS therapy for epilepsy was associated with a sustained and statistically significant reduction in seizure frequency from baseline that continued to improve over time: 69% median seizure reduction from baseline at five years and 41% at one year.
Saluda Medical secures US$10 million in new financing
Saluda Medical has announced that it has received US$10 million in Series B financing bringing a breakthrough treatment for chronic pain one step closer to reality.
Development of personalised cellular therapy for brain cancer
Preclinical study results pave the way for newly-opened clinical trial of immune cells engineered to attack protein found on tumours in 30% of patients with glioblastoma.
New device improves healing of some ruptured aneurysms
Research presented at the American Stroke Association's International Stroke Conference (Nashville, USA, 11-13 February, 2015) suggests that a new device inserted into small ruptured brain aneurysms significantly improved healing of ruptured aneurysms compared to a standard device.
Blood flow technology from VasSol Identifies risk of recurrent stroke
The results, presented at the International Stroke Conference (Nashville, USA, 11-13 February, 2015) are expected to substantially improve both the study and treatment of stroke.
Caputron Medical signs distribution agreement with Neurosoft
The distribution agreement gives Caputron Medical the rights to market the Neuro-MS/D Diagnostic, Therapeutic, and Advanced Therapeutic rTMS stimulators in the USA and Canada.
American Stroke Association and Medtronic collaborate to reduce recurrent strokes
The two organisations will work together over several years to educate, raise awareness and support effective management of patients who have strokes.
Stem cell transplants may work better than existing drug for severe...
Those who received the stem cell transplants had 80% fewer new areas of T2 lesions than those who received mitoxantrone.
US stroke patients receiving better and more timely care
More ischaemic stroke patients are now being quickly transferred to certified US stroke centres, according to research presented at the American Stroke Association's International Stroke Conference 2015.
Mobile stroke units improve response times and outcomes for patients
There was a significant reduction of median alarm to CT scan completion times-41 minutes in MSTU vs. 62 minutes in emergency room patients.
Groundbreaking studies find that neurointerventional surgery reduces stroke mortality
Two new clinical trials on the treatment of stroke (ESCAPE and EXTEND IA) demonstrate that neurointerventional surgery significantly increases the number of patients who are able to live independently without major neurological disabilities.
Creatine does not slow rate of Parkinson’s disease progression
Treatment with creatine monohydrate for at least five years for patients with early and treated Parkinson's disease failed to slow clinical progression of the disease, compared with placebo, according to a study in JAMA.
Human stem cells repair damage caused by radiation therapy for brain...
Investigators used lab-grown oligodentrocyte progenitor cells to treat rats that had been exposed to brain irradiation.
FDA clears Enroute transcarotid neuroprotection system
The Enroute system (Silk Road Medical) is a first in class system used to directly access the common carotid artery and initiate high rate temporary blood flow reversal to protect the brain from stroke while performing carotid angioplasty and stenting.
Trial results show Brainsway deep TMS to be efficacious and safe...
A multicentre double blinded randomised controlled trial has shown Brainsway deep TMS (transcranial magnetic stimulation) to be efficacious and safe for drug-resistant depression, with a stable effect over three months of maintenance treatment.
FDA approves Pipeline Flex embolisation device
Designed to divert blood flow away from an aneurysm, the Pipeline Flex embolisation device (Medtronic) features a braided cylindrical mesh tube that is implanted across the base or neck of the aneurysm.
Transradial access valid for treatment of acute ischaemic stroke
According to a recent retrospective review published in the Journal of NeuroInterventional Surgery, the transradial approach to mechanical embolectomy is a valid approach for the endovascular treatment of acute ischaemic stroke.
NeuroPace RNS system reduces seizures and improves quality of life for...
Long-term treatment study data show sustained effectiveness in adults historically resistant to other treatments.
BrainStorm announces positive DSMB recommendation in ongoing NurOwn amyotrophic lateral sclerosis...
The DSMB did not find any lab abnormalities, adverse events or significant protocol deviations that would be cause for concern.
Heavy drinking in middle-age may increase stroke risk more than traditional...
In a study of 11,644 middle-aged Swedish twins who were followed for 43 years, researchers compared the effects of an average of more than two drinks daily to less than half a drink daily.
Low-frequency deep brain stimulation improves difficult-to-treat Parkinson’s symptoms
60Hz stimulation more effective than standard treatment at improving swallowing and gait issues
Review confirms that electroCore’s non-invasive vagus nerve stimulation is safe and...
The review examined the efficacy of both surgically implanted non-invasive vagus nerve stimulation, including electroCore's gammaCore device.
Brain imaging may help predict future behaviour
Brain imaging can help predict an individual’s future learning, criminality, health-related behaviours, and response to drug or behavioural treatments.
Stem cell transplantation shows potential for reducing disability in multiple sclerosis...
Treatment with nonmyeloablative hematopoietic stem cell transplantation was associated with improvement in measures of disability and quality of life
Siemens Healthcare and IMRIS bring hybrid ORs to Sahlgrenska University Hospital...
This sale involves both radiology and MRI systems in four hybrid operating rooms for the hospital’s new imaging centre with clinical opening planned in 2016.
Link discovered between protective effects of cooling on the brain and...
Researchers have identified a protective mechanism that activates when body temperature is lowered, initiating a process that prevents the loss of brain cells and the connections between them.
InVivo Therapeutics announces reopening of enrolment for ongoing pilot trial
This is the company's first clinical study of its investigational degradable polymer Neuro-Spinal Scaffold to treat patients with acute spinal cord injury.
Ischaemic micro-lesions associated with flow-diverting stents in treatment of intracranial aneurysms
Researchers from Dupuytren University Hospital, Limoges, France, conducted a study to determine the extent of these complications and their implications on clinical outcomes in flow-diverting stent treatments.
Non-invasive EEG reveals depolarisations
New research at the University of Cincinnati Neuroscience Institute has shown that spreading depolarisations can be measured by the placement of electroencephalograph (EEG) electrodes on the scalp. Head of the research team, Jed Hartings speaks to NeuroNews about the discovery and its potential to change current practice.
PulseRider safe and effective in early USA experience
Initial experience with PulseRider (Pulsar Vascular) has shown the device to be safe and effective as an adjunct in the treatment of bifurcation aneurysms arising at the basilar apex or carotid terminus.
Publication demonstrates high accuracy for identification of acute stroke
BrainScope has announced the publication of an independent study that demonstrated the potential clinical utility of its traumatic brain injury technology to identify acute stroke in the hospital Emergency Department setting.
Update regarding coverage of VNS Therapy system in treatment-resistant depression
Cyberonics has announced the receipt of a decision from the Departmental Appeals Board (DAB) of the Department of Health and Human Services in the USA.
Stem cell transplants for Parkinson’s disease edging closer
A major breakthrough in the development of stem cell-derived brain cells has put researchers on a firm path towards the first ever stem cell transplantations in people with Parkinson's disease.
Can exercise help people with Parkinson’s disease?
Exercise may help people with Parkinson's disease improve their balance, ability to move around and quality of life, even if it does not reduce their risk of falling, according to a new study published in the online issue of Neurology.
Stroke falls to No. 5 cause of death in USA
Stroke has dropped from the USA's fourth-leading cause of death to No. 5, according to new federal statistics.
Stem cell transplants may halt progression of multiple sclerosis
Three-year outcomes suggest that high-dose immunosuppressive therapy followed by transplantation of a person's own blood-forming stem cells may induce sustained remission in some people with relapsing-remitting multiple sclerosis.
NeuroMetrix to showcase Quell wearable pain relief technology
NeuroMetrix will unveil and demonstrate Quell, a novel wearable pain relief device at the 2015 International Consumer Electronics show.
Seventy-one teams to compete in NIH Neuro Startup Challenge
The Challenge has teams competing to commercialise 16 National Institutes of Health-conceived and -developed inventions involving therapeutics, diagnostics, prognostics, and medical devices for a range of brain diseases.
Alcyone Lifesciences appoints Michael Rogawski to Clinical and Scientific Advisory Board
Rogawski is an internationally recognised expert on treatments for seizures and epilepsy.
Longer cooling, lower temperature no improvement for infant oxygen deprivation
The standard treatment for newborns whose brains were deprived of oxygen appears to work better than proposed alternatives, according to a study from a National Institutes of Health research network.
CHMP recommends approval of Xadago to treat Parkinson’s disease in the...
The EU Committee for Medicinal Products for Human Use (CHMP) recommended that the European Commission approve the use of Xadago (safinamide) as add-on to L-dopa alone or in combination with dopamine agonists, entacapone, amantadine, and/or anticholinergics, for the treatment of patients with mid-late stage Parkinson’s disease experiencing motor fluctuations despite being stabilised on 'Standard of Care'.
MR CLEAN: Better outcomes with intervention in ischaemic stroke patients
For the first time, the Multicentre randomised clinical trial of endovascular treatment for acute ischaemic stroke in the Netherlands (MR CLEAN) has shown better outcomes in favour of intervention in patients with acute ischaemic stroke.
American Academy of Neurology calls for more research on medical marijuana...
The AAN supports the reclassification of marijuana-based products by the federal government to improve access for study of marijuana or cannabinoids under approved research protocols.
Brainlab multiple metastases planning software available in the USA
Adaptive Hybrid Surgery and Automatic Brain Metastases Planning software by Brainlab are now available in the USA after successful clinical use in several international markets.
Stroke treatment in England varies widely by location
The figures released by the HSCIC show that the percentage of patients admitted to an acute stroke unit within four hours of arrival at hospital varied from 22% to 85% across different clinical commissioning groups.
Cyberonics reports positive results from AspireSR generator vagus nerve stimulation studies
The E-36 and E-37 studies assessed the acute impact of the AspireSR generator on seizure duration and termination, as well as the long-term evaluation of safety, clinical benefit of the automatic stimulation feature, and quality of life.
Brainsway receives IDE approval from FDA for launching pivotal PTSD multicentre...
Brainsway has announced that it has received an IDE (Investigational Device Exemptions) approval from the FDA for launching a multicentre trial which will examine the effectiveness of Brainsway's Deep TMS (deep transcranial magnetic stimulation) for treating PTSD (post-traumatic stress disorder) patients.
Research shows promise for the DRG as a target for neuromodulation
At the 18th annual North American Neuromodulation Society (NANS) congress, researchers presented 20 international, peer-reviewed scientific abstracts from Australia and Europe highlighting clinical results of the Axium neurostimulator system for the treatment of chronic, intractable pain.
Memory lapses among highly educated may signal higher stroke risk
People with a high level of education who complain about memory lapses have a higher risk for stroke, according to new research in the American Heart Association journal Stroke.
Acorda initiates phase 3 trial of CVT-301 in Parkinson’s disease
Acorda Therapeutics has enrolled its first patient in a phase 3 study of CVT-301 for the treatment of "off" episodes in Parkinson's disease.
Images of brain after mild stroke predict future risk
A CT scan of the brain within 24 hours of a mild, non-disabling stroke can predict when patients will be at the highest risk of another stroke or when symptoms may worsen.
First US patients receive Genzyme’s Lemtrada following FDA approval
Genzyme has announced that the first US patients have initiated treatment with Lemtrada in the commercial setting following its FDA approval for the treatment of patients with relapsing forms of multiple sclerosis.
Brainsway receives CE approvals for treating MS, stroke and obsessive compulsive...
Brainsway has announced that it has received a CE marketing approval, enabling it to immediately market and sell Brainsway deep TMS (deep transcranial magnetic stimulation) in Europe, for treatment of multiple sclerosis (MS), stroke and obsessive compulsive disorder (OCD).
Spinal Modulation completes enrolment of US pivotal trial evaluating the Axium...
The Axium system is a targeted form of spinal cord stimulation (SCS), which uses an implantable medical device to deliver mild electrical pulses that mask or interrupt pain signals as they travel from the periphery to the brain.
IMRIS completes SYMBIS surgical system human factors study
IMRIS has successfully completed the human factors study for the SYMBIS surgical system - the validation used to support the product's 510(k) submission to the US Food and Drug Administration.
Eli Lilly and Company and AstraZeneca initiate early Alzheimer’s disease pivotal...
Eli Lilly and Company and AstraZeneca have announced enrolment of the first patient into AMARANTH, a phase II/III study of an oral beta secretase cleaving enzyme inhibitor currently in development as a potential treatment for Alzheimer's disease.
Same regions in brain are vulnerable to both Alzheimer’s and schizophrenia
Researchers have found a specific network of brain regions that is not only more vulnerable to unhealthy ageing, for example, Alzheimer's disease, but also to disorders that emerge in young people, such as schizophrenia.
InVivo Therapeutics announces OHSU as fifth clinical trial site for Neuro-Spinal...
InVivo Therapeutics has announced that the Oregon Health & Science University (OHSU) in Portland, Oregon, USA, is the fifth clinical site in the company's ongoing IDE pilot study of its Neuro-Spinal Scaffold in patients with acute spinal cord injury (SCI).
Repetitive transcranial magnetic stimulation studied for stroke rehabilitation
Researchers at The Ohio State University Wexner Medical Center are attempting to improve arm movement in stroke patients by using a transcranial magnetic stimulator (TMS) device.
New Alzheimer’s programme to focus on prevention, intervention, research and support
Cedars-Sinai has launched the Alzheimer's Prevention Program to help identify patients at risk of developing the neurological disorder and to reduce the impact on those diagnosed with the condition.
Barrow neurosurgeons implant the world’s first scaffold into a patient’s spinal...
Performed last month, the surgery involves inserting a bioresorbable scaffolding implant to act as a bridge across the gap of the injured section of the cord in an attempt to help the spinal cord heal.
Portable electric device found to slow and reverse growth of glioblastoma
A non-invasive, portable electrical device has been found to lengthen the lives of some patients suffering from glioblastoma, the most common and deadliest form of brain cancer.
FDA clears Ahead 100 device for adjunctive assessment of traumatic brain...
The Ahead 100 from BrainScope uses a patient's electroencephalograph (EEG) to provide an interpretation of the structural condition of the patient's brain after head injury.
MR CLEAN: expert opinion
Since the first presentation of data at the World Stroke Congress, the MR CLEAN trial has sent a ripple across the entire neurointerventional arena, raising questions about the future of stroke treatment and the fate of similar trials, some of which have already been halted.
Majority of UK neurosurgical units following published recommendations, but room for...
It has been discovered via a UK national survey of current practice that the majority of neurosurgical units have been following most of the key recommendations for the management of aneurysmal subarachnoid haemorrhage.
CE mark for new Asahi Intecc neurovascular guide wires
Asahi Intecc has received CE certification of neurovascular guide wires: Asahi Chikai 008, Asahi Chikai black, and Asahi Chikai black 18 and is initiating sales in Europe.
Lazarus Effect Cover device receives CE mark
The Lazarus Cover is a nitinol-mesh cover that surrounds a retriever device and captures material during removal from a blood vessel.
Studies support the use of the CyberKnife system as a safe...
Accuray Incorporated has announced that studies presented at the 15th European Congress of Neurosurgical Societies (EANS) in Prague, October 12 - 17, 2014 reinforce the benefits of the CyberKnife robotic radiosurgery system for the treatment of neurological diseases such as meningiomas, acoustic neuromas, trigeminal neuralgia, and spinal tumours.
NeuroSigma receives notice of allowance for subcutaneous trigeminal nerve stimulation patent
The patent application is related to the use of trigeminal nerve stimulation with minimally invasive, subcutaneously implanted electrodes and pulse generator for the treatment of a wide variety of medical disorders.
ALS Association triples research spending following ice bucket donations
The ALS Association Board of Trustees has developed a long-term strategy for leveraging the Ice Bucket Challenge donations it has received to advance its integrated mission of leading the fight to treat and cure ALS through global research, care services and public policy.
American Shared Hospital Services announces 2015 CMS gamma knife and proton...
American Shared Hospital Services has announced that the Centers for Medicare and Medicaid Services has posted its final Medicare hospital outpatient prospective payment rates for calendar year 2015. The rates for gamma knife and proton therapy remained as proposed earlier this year.
Over US$30m in funding allocated to rare brain disease research
Researchers studying frontotemporal degeneration disease, a leading cause of early onset dementia, will receive more than US$30m over the next five years in grants from the National Institutes of Health (NIH).
Diets high in fruit, vegetables, whole grains and nuts lower first-time...
Eating Mediterranean or DASH-style diets, regularly engaging in physical activity and keeping blood pressure under control can lower a person's risk of a first-time stroke.
Researchers join Biogen Idec to advance drug discovery for neurodegenerative diseases
Two leading neuroscientists have joined Biogen Idec to advance its research in neurodegenerative diseases.
New test to help brain injury victims recover
A dynamic new assessment for helping victims of trauma to the brain, including those suffering from progressive conditions such as dementia, has been developed by a clinical neuropsychologist at the University of Leicester, UK.
Traumatic brain injury associated with increased dementia risk in older adults
Traumatic brain injury appears to be associated with an increased risk of dementia in adults 55 years and older, according to a study published online by JAMA Neurology.
Encouraging trial results for electroCore’s non-invasive vagus nerve stimulation treatment for...
In an open label trial, electroCore's handheld non-invasive vagus nerve stimulation device gammaCore, completely resolved 44.8% of migraines within 30 minutes, with an additional 11.4% experiencing moderate benefits (incomplete resolution of their headaches) by two hours.
The Roskamp Institute discovers new target for drugs to treat Alzheimer’s...
Scientists at the Roskamp Institute have isolated a key molecule that gives researchers a new drug target for the treatment of the progressive, irreversible neurological disorder. This finding is the culmination of more than 10 years of work by more than a dozen scientists and clinicians in the research team in Sarasota.
Thymosin beta-4 crosses blood-brain barrier in animal stroke model
Researchers from RegeneRx Biopharmaceuticals have reported on study findings in which thymosin beta-4 crossed the blood-brain barrier in an animal stroke model.
Costs to treat bleeding strokes increases 10 years later
Costs to treat strokes caused by bleeding in the brain may increase significantly 10 years later, according to a study in the American Heart Association journal Stroke.
ALS Association and NEALS issue request for proposals for phase II...
ALS ACT, the ALS Association, and NEALS clinical trials have announced a call for phase II clinical trial applications for novel, high-potential treatments in amyotrophic lateral sclerosis (ALS).
New NICE guidance to tackle inequalities in multiple sclerosis care
People with multiple sclerosis should be offered a rapid and accurate diagnosis of their condition and access to specialist advice and proven therapies, says the National Institute for Healthcare and Excellence.
A new window of opportunity to prevent cardiovascular and cerebrovascular diseases
Mount Sinai experts show neuroimaging tests can reveal disruptive brain changes resulting from vascular disease risk factors before the appearance of any signs or symptoms of cardiovascular or cerebrovascular disease.
Codman Neuro launches first disposable forceps with dual irrigation
Codman Neuro has launched the Spetzler Malis dual irrigating disposable non-stick bipolar forceps, the first disposable dual irrigating forceps for neurosurgery.
Stenting safe and effective for long-term stroke prevention
Using stents to keep neck arteries open is just as effective as invasive neck surgery for long-term prevention of fatal and disabling strokes, reports an international trial led by University College London.
AVP-923 phase II results in Alzheimer’s patients presented at ANA meeting
Results from the phase II study evaluating AVP-923 for the treatment of agitation in patients with Alzheimer's disease were presented at the 2014 American Neurological Association meeting.
FDA and CE mark approval for new CoverEdge surgical leads
Boston Scientific has received FDA and CE mark approval for the CoverEdge 32 and CoverEdge X 32 surgical leads, designed for use with the Precision Spectra spinal cord stimulator system.
Delay the Disease Parkinson’s programme gets participants moving again
OhioHealth "Delay the Disease" is designed to empower those living with Parkinson's disease by optimising their physical function and helping to delay the progression of symptoms associated with the disease.
First patient enrolled in pilot spinal cord injury trial
The objective of the pilot study is to evaluate the safety and feasibility of the Neuro-Spinal Scaffold (InVivo Therapeutics) as well as to gather preliminary evidence of effectiveness.
NeuroSigma partners with US Veterans Administration for eTNS trial
NeuroSigma has has entered into a Cooperative Research and Development Agreement with the US Veterans Affairs for a phase I clinical trial to evaluate the benefits of non-invasive, external trigeminal nerve stimulation (eTNS) for patients with traumatic brain injury.
Drug-eluting balloon angioplasty shows excellent results for refractory recurrent carotid in-stent...
A long-term follow-up study reports on the safety and success of drug-eluting balloon angioplasty in treating patients with carotid in-stent restenosis that has proven refractory to treatment with balloon angioplasty and/or redo stenting.
Disputed theory on Parkinson’s origin strengthened
Researchers at Lund University, Sweden, have mapped the spread of Parkinson's disease from the gut to the brain in rat models.
Treeway BV and Leiden Academic Center for Drug Research collaborate on...
Treeway and Leiden Academic Center for Drug Research (LACDR) at the University of Leiden join forces and form a collaboration focused on the optimisation of clinical trial designs and data-analysis for ALS through the use of population disease progression models.
Neuravi receives US patents for neurovascular clot capture and retrieval
Neuravi has announced that the US Patent Office has approved two patents covering its therapeutic platform for the endovascular treatment of acute ischaemic stroke.
Mechanism that repairs brain after stroke discovered
A previously unknown mechanism through which the brain produces new nerve cells after a stroke has been discovered at Lund University and Karolinska Institutet in Sweden.
New Envoy catheters launched
Codman Neuro has announced the Europe, Middle East and Africa launch of the Envoy DA XB Distal Access Guiding Catheter and the 7F Envoy Guiding Catheter for neurovascular procedures.
Neuroscientists claim rare pair of research grants
In a rare distinction for one university, neuroimaging world leaders and University of Southern California (USC) Professors Arthur Toga and Paul Thompson will receive two major research centre awards to advance their exploration of the human brain.
IMRIS intraoperative imaging solutions to be featured at CNS
IMRIS has announced that use of intraoperative imaging for optimising workflow with neurosurgical focal therapies will be featured in its exhibition space at the Congress of Neurosurgical Surgeons (CNS) meeting (20-22 October, Boston, USA).
First patient treated in US pivotal trial evaluating cerebral protection during...
The randomised controlled SENTINEL Trial is the first in the USA to study capture and removal of debris released during TAVI that may otherwise be the source of stroke.
Kadimastem approached the FDA regarding its ALS treatment
Israeli biotechnology company Kadimastem has announced that it has approached the FDA regarding the cellular treatment it is developing for ALS. In the framework of talks with the FDA, Kadimastem intends to consolidate a preliminary outline for its continuing trials for this indication.
ALS Association announces initial commitment of US$21.7 million from Ice Bucket...
The ALS Association has approved an initial expenditure of US$21.7 million in funding to support six programmes and initiatives to expedite the search for treatments and a cure for amyotrophic lateral sclerosis (ALS). Additionally, US$12.5 million in matching donations bring the total commitment to US$34.2 million.
IMRIS horseshoe headrest named Life Sciences Alley New Technology Showcase winner
IMRIS announced that its horseshoe headrest has been selected one of 10 New Technology Showcase Winners by Twin Cities-based Life Sciences Alley (LSA), the USA's largest regional medical industry association.
Collaboration established to advance diagnostic candidate to detect CTE in former...
Aethlon Medical and its diagnostic subsidiary, Exosome Sciences, have announced that a clinical collaboration with the Boston University CTE Center has been established to advance a blood-based diagnostic candidate that could identify Chronic Traumatic Encephalopathy (CTE) in living individuals.
Medina Medical announces CE mark for its embolisation coil
Medina Medical has announced that it has received CE mark authorisation for its Embolization Framing Coil for commercial distribution in the European Union.
Neuralstem ALS investigator presents long-term follow-up phase I data
Neuralstem has announced that Jonathan D Glass presented long-term follow up data on the phase I trial testing NSI-566 human neural stem cells in the treatment of amyotrophic lateral sclerosis (ALS).
Randomised data show gammaCore significantly reduces cluster headache attack frequency
A large scale randomised clinical trial of the gammaCore therapy in chronic cluster headache not only significantly reduced the number of cluster headache attacks beyond the best available standard of care, but patients also experienced a greater reduction in number of attacks the longer they stayed on treatment.
EBS expands commercialisation of Next Wave non-invasive electrical brain stimulation device
The EBS Next Wave brain stimulation device is designed to expand the visual field of patients with impaired vision caused by glaucoma, stroke and other neurological diseases.
Neuroimaging technique identifies concussion-related brain disease in living brain
An experimental positron emission tomography (PET) tracer is effective in diagnosing concussion-related brain disease while a person is still alive, according to a case study.
Nexstim plans an Initial Public Offering on NASDAQ OMX First North
Nexstim has announced its intention to proceed with an Initial Public Offering of Nexstim on NASDAQ OMX First North Finland and NASDAQ OMX First North Sweden ("Admission"). It is expected that the Admission will occur in the 4th Quarter of 2014.
ATL1102 phase II trial results published in Neurology
Antisense Therapeutics has reported the publication of previously generated phase IIa clinical trial data on ATL1102 in the medical journal Neurology.
Evidence supports deep brain stimulation for obsessive-compulsive disorder
Available research evidence supports the use of deep brain stimulation for patients with obsessive-compulsive disorder who do not respond to other treatments, concludes a review in the October issue of Neurosurgery.
Mayo researchers reveal pathway that contributes to Alzheimer’s disease
Researchers have discovered a defect in a key cell-signalling pathway they say contributes to both overproduction of toxic protein in the brains of Alzheimer's disease patients as well as loss of communication between neurons - both significant contributors to this type of dementia.
Multiple sclerosis drug candidate shows new promise
Positive new data have been released on a drug candidate for relapsing multiple sclerosis that was first discovered and synthesised at The Scripps Research Institute.
CE mark for Vercise deep brain stimulation system for patients with...
Boston Scientific has received CE mark approval for the Vercise deep brain stimulation system for the treatment of tremor, including the most common form of this movement disorder known as essential tremor.
New mobile apps support education, safety, and adherence needs of seizure...
Adherent Health has announced the introduction of patient support apps for two novel medications used in the treatment of seizures and epilepsy, Oxtellar XR (oxcarbazapine extended-release tablets) and Trokendi XR (topiramate extended-release capsules).
Lilly and AstraZeneca announce alliance to co-develop potential treatment for Alzheimer’s...
Eli Lilly and AstraZeneca have announced an agreement to co-develop and commercialise AZD3293, an oral beta secretase cleaving enzyme (BACE) inhibitor currently in development as a potential treatment for Alzheimer's disease.
Covidien begins enrolment in two neurovascular clinical trials
Covidien has announced the start of enrolment in two clinical trials designed to further underscore the safety and effectiveness of the company's advanced neurovascular solutions.
IMRIS sterile wireless imaging coil and Monteris laser technologies combine for...
This combination brought improved visualisation and workflow in removing a patient's low-grade glioma brain tumour inside a VISIUS Surgical Theatre.
Codman Neuro gains exclusive rights to market and promote PulseRider in...
PulseRider is a minimally invasive device intended for use with embolic coils in the treatment of unruptured wide-neck intracranial aneurysms originating on or near a bifurcation.
Understanding the brain’s pulse shows promise for managing concussion
An article published in the Clinical Journal of Sport Medicine - "Detection of Concussion Using Cranial Accelerometry" - has shown that the Jan Medical Nautilus BrainPulse technology has detected a consistent pattern correlated with concussion.
Revive SE thrombectomy device approved in China, South Korea and Taiwan
The Revive SE Device from Codman Neuro is designed to ease navigation through small and tortuous blood vessels and arteries in the cerebral vasculature. The new device enables rapid restoration of blood flow to the brain during an acute ischaemic stroke.
Neuravi introduces collaborative clot research initiative at ESMINT
The Neuravi Thromboembolic Initiative brings together Neuravi engineers with clinicians and researchers in an effort to deepen the understanding of the mechanical properties of clot and occlusion dynamics, with the goal of improving the physician's ability to restore flow in acute ischaemic stroke.
Diplomat to distribute Plegridy (peginterferon beta-1a) for treatment of multiple sclerosis
Manufactured by Biogen Idec, Plegridy was approved on 15 August 2014 by the US Food and Drug Administration for the treatment of relapsing forms of multiple sclerosis (RMS).
GeNeuro phase 2a study reinforces novel approach to treat multiple sclerosis
GeNeuro has announced positive results from a one-year, open-label extension of a phase IIa study.
High accuracy for identification of traumatic intracranial haematomas with BrainScope, study...
The publication of an independent, prospective validation study has demonstrated the potential clinical utility of the BrainScope technology for the identification of acute traumatic intracranial haematomas in patients who present to hospital emergency departments.
National charity unveils big new ambitions for children with brain injury
The UK's leading charity for children with brain injury has launched a new three-year strategy, outlining ambitious plans to reach thousands more children and families across the UK.
NICE approves Tecfidera (dimethyl fumarate)
NICE has approved Tecfidera as an option for treating adults with active relapsing remitting multiple sclerosis.
Aggressive resection should be considered for paediatric epilepsy
Physicians from the University of California, San Francisco, USA, report that resection is safe and effective in children with pharmacoresistant focal epilepsy.
Alzheimer’s Prevention Registry reaches recruitment milestone of 40,000 individuals
The online Registry (www.endALZnow.org) aims to accelerate research by connecting healthy individuals who are committed to preventing Alzheimer's with scientists carrying out the studies.
Medtronic acquires Sapiens Steering Brain Stimulation
Medtronic has announced that it has acquired Sapiens Steering Brain Stimulation (Sapiens SBS) for approximately US$200 million in an all-cash transaction.
US Army funds phase II trial for treatment of PTSD with...
NeuroSigma has announced that the US Department of the Army, through the US Army Medical Research and Material Command, has funded a phase II clinical trial aimed at examining the use of external eTNS as treatment for post-traumatic stress disorder.
Highest level evidence indicates better outcomes when using iMRI for brain...
In a recently published article in the journal Neurosurgery the use of VISIUS intraoperative MRI (iMRI) in brain tumour surgery has been proven to result in complete tumour removal in more patients with glioma tumours.
Covidien acquires Reverse Medical Corporation
Covidien has announced that it has acquired Reverse Medical Corporation, a privately held medical device company focused on expanding the management of vascular disease. Financial terms of the transaction were not disclosed.
New non-invasive technique controls the size of molecules penetrating the blood-brain...
The innovative ultrasound approach uses acoustic pressure to let molecules through-may help treatment for central nervous system diseases like Parkinson's and Alzheimer's.
Utah team invents way to image brains of mice using small...
A University of Utah team discovered a method for turning a small, US$40 needle into a 3D microscope capable of taking images up to 70 times smaller than the width of a human hair.
New dementia research reveals overwhelming demand for “the value of knowing”
Three out of four people would want to know what kind of neurological disorder they had even if there was no cure, according to new global research from GE Healthcare.
Stemedica International announces pre-clinical data of Alzheimer’s study
The first pre-clinical mouse study using ischaemia-tolerant mesenchymal stem cells (itMSCs) shows over 30% decrease in amyloid beta (Abeta) plaques.
electroCore appoints Piper Jaffray to deal with growing interest from pharma
electroCore has appointed Piper Jaffray to assist in discussions with pharma companies who are interested in partnering on the commercialisation of its non-invasive vagus nerve (nVNS) stimulation therapy.
Low education, smoking, high blood pressure may lead to increased stroke...
Adult smokers with limited education face a greater risk of stroke than those with a higher education, according to new research in the American Heart Association's journal Stroke.
Plegridy (peginterferon beta-1a) approved in the USA for treatment of multiple...
Biogen Idec has announced that the US Food and Drug Administration has approved Plegridy (peginterferon beta-1a), a new treatment for people with relapsing forms of multiple sclerosis.
Enrolment in NeuroSTAT phase II study continues
Enrolment to the ongoing clinical phase IIa study with NeuroVive's drug candidate NeuroSTAT for treating patients with severe traumatic brain injury is continuing, and another two patients have been enrolled.
IMRIS intraoperative imaging moving system and coils patents granted in Japan
The patents cover control of effective MR imaging using a movable system; imaging coils where clarity is maintained when used while in position during X-ray use; and other components related to using both MR and X-ray imaging in the same environment.
NeuroPace RNS system receives approval from CMS for new Technology Add-On...
NeuroPace has announced that the Centers for Medicare & Medicaid Services (CMS) has approved New Technology Add-on Payments (NTAP) for the RNS system, the world's only commercially available implantable closed-loop responsive neurostimulator system.
AcuteCare Telemedicine and Colleton Medical Center partner to improve patient access...
AcuteCare Telemedicine continues to expand its presence in the Southeastern region with the addition of new client hospitals.
GE Healthcare’s Signa PET/MR 510(k) pending at FDA
GE Healthcare has announced that the first integrated, simultaneous, time-of-flight (TOF) capable, whole body Signa PET/MR is 510(k) pending at the US Food and Drug Administration.
Accenture and Philips announce proof of concept app for ALS patients
Royal Philips and Accenture have announced that they have developed proof of concept software connecting a wearable display to Emotiv Insight Brainware that could ultimately give more independence to patients with amyotrophic lateral sclerosis (ALS) and other neurodegenerative diseases.
Final patient treated in Neuralstem phase II ALS stem cell trial
Neuralstem has announced that the final patient was treated in its phase II trial using NSI-566 spinal cord-derived neural stem cells in the treatment of amyotrophic lateral sclerosis (ALS or Lou Gehrig's disease).
NeuroDerm announces eligibility for European Union centralised procedure for ND0612H
NeuroDerm has announced that the European Medicines Agency (EMA) has deemed ND0612H, its product candidate offering continuous delivery of levodopa/carbidopa (LD/CD) treatment for advanced Parkinson's disease, eligible for a European Union marketing authorisation application procedure ("centralised procedure").
Los Angeles medical team performs California’s first auditory brainstem implant surgery...
A Los Angeles team of scientists and surgeons reported that sound registered in the brain of a deaf Canadian boy for the first time after doctors activated a hearing device that had been surgically implanted in his brainstem.
New technology may improve visualisation of the brain during stroke treatment
New technology in the form of a magnetically-assisted remote-controlled catheter (MARC) which could allow physicians to see and assess brain tissue more clearly while treating a stroke may hold promise.
SNIS Foundation bestows first grant award for cutting-edge neurointerventional research
The Society of Neurointerventional Surgery (SNIS) Foundation recognised its first Seed Grant awardee with US$25,000 to fund a translational research project.
IMRIS receives CE mark for integrating latest generation MR scanners within...
IMRIS has announced that it has obtained regulatory CE mark for integrating the next generation MRI core technology into the VISIUS surgical theatre allowing for sales and marketing in the European Union.
Medtronic completes acquisition of Visualase
Medtronic has announced that it has completed the acquisition of Visualase, a privately held company based in Houston, USA, that develops and markets an FDA-approved MRI-guided laser and image guided system for minimally invasive neurosurgeries, including surgical thermal ablation.
NeuroPace RNS system will play key role in DARPA’s RAM programme
NeuroPace has announced its partnership with the Defense Advanced Research Projects Agency (DARPA) Restoring Active Memory (RAM) teams at the University of Pennsylvania and the University of California, Los Angeles (UCLA), USA to develop new treatments for memory deficits using neurostimulation.
Plegridy (peginterferon beta-1a) approved in the EU for treatment of multiple...
Biogen Idec has announced that the European Commission has granted marketing authorisation for Plegridy (peginterferon beta-1a) as a treatment for adults with relapsing-remitting multiple sclerosis.
US$1 million Career Development Award grant for glioblastoma research with ThermoDox...
The grant will support preclinical studies evaluating ThermoDox, heat-activated liposomal encapsulation of doxorubicin, in combination with High Intensity Focused Ultrasound (HIFU), for the treatment of brain tumours.
Scientists find new clues to brain’s wiring
New research provides an intriguing glimpse into the processes that establish connections between nerve cells in the brain. These connections, or synapses, allow nerve cells to transmit and process information involved in thinking and moving the body.
Study links enzyme to Alzheimer’s disease
Unclogging the body's protein disposal system may improve memory in patients with Alzheimer's disease, according to a study from scientists at Kyungpook National University in Korea published in The Journal of Experimental Medicine.
JAMA study: Stroke risk and death rates fall over past two...
Fewer Americans are having strokes and those who do have a lower risk of dying from them finds a new study led by Johns Hopkins Bloomberg School of Public Health researchers.
Making a mental match: Pairing a mechanical device with stroke patients
Georgia Tech researchers have created a mechanical device intended to help stroke victims. Their functional MRI-compatible hemiparesis rehab device creates a long latency stretch reflex at the exact time as a brain signal.
Stroke inpatient rehabilitation facilities yield better neurological outcomes than skilled nursing...
A demographic analysis has revealed that an association exists between discharge disposition and National Institutes of Health Stroke Scores (NIHSS) at 90-day follow-up.
Banner Alzheimer’s Institute partners with Novartis in new study of Alzheimer’s...
The study is to determine whether two investigational anti-amyloid drugs can prevent or delay the emergence of symptoms of Alzheimer's in people at particularly high risk for developing the disease at older ages.
C2N expands partnership with Washington University School of Medicine
The objective of this collaboration is to commercialise a clinical blood test for detecting the earliest stages of Alzheimer's disease as well as mild cognitive impairment.
Worldwide Alzheimer’s and dementia epidemic grows
While the global epidemic of Alzheimer's disease continues to grow, new data on lower incidence in the "youngest old" from developed countries in Europe and the United States suggest the possibility of reducing risk and/or preventing the disease, according to the results of several research studies.
Post-concussion ‘return to play’ decision for footballers should be made solely...
An editorial published in The Lancet Neurology calls for sports authorities to take into consideration the long-term neurological problems that repeated concussions can cause.
New data shows combination therapy is more effective than monotherapy in...
Data results found that combination therapy was more effective in removing clumps of amyloid-beta protein in the brain - a component that is thought to lead to Alzheimer’s disease - than use of one therapy.
Cataract surgery improves not only vision but cognition and quality of...
Cataract surgery for people with Alzheimer’s disease and other dementias not only improves vision but can slow decline in cognition and improve quality of life for both people with the disease and their caregivers, according to clinical trial results reported at the Alzheimer’s Association International Conference 2014 (AAIC) in Copenhagen, Denmark.
Potential Alzheimer’s disease risk factors and risk reduction strategies become clearer
Participation in activities that promote mental activity, and moderate physical activity in middle age, may help protect against the development of Alzheimer's disease and dementia in later life according to new research.
Looking back on 40 years of the Glasgow Coma Scale
A group of leading brain injury specialists look back on 40 years of the Glasgow Coma Scale and outline the continuing role of the scale in research and clinical practice, in a new Personal View published in The Lancet Neurology.
High stress, hostility, depression linked with increased stroke risk
Higher levels of stress, hostility and depressive symptoms are associated with significantly increased risk of stroke in middle-age and older adults, according to new research in Stroke.
New US patent for Barrel vascular reconstruction device
This new patent grants six claims surrounding the use of the company's Barrel vascular reconstruction device technology platform.
NIH funds phase II trial for treatment of ADHD with Monarch...
NeuroSigma has announced that the US National Institutes of Health (NIH) has awarded UCLA a grant that funds a phase II 90-subject paediatric clinical trial focused on the treatment of Attention Deficit Hyperactivity Disorder (ADHD) with the Monarch eTNS system.
Northwestern Medicine enrols first participant in study of device to treat...
According to doctors, the device could offer hope for patients with large, wide-neck brain aneurysms previously considered untreatable.
Cinnamon may be used to halt the progression of Parkinson’s disease
Neurological scientists at Rush University Medical Center have found that using cinnamon can reverse the biomechanical, cellular and anatomical changes that occur in the brains of mice with Parkinson's disease.
Less-invasive technique repairs life-threatening condition
A patient who underwent a less-invasive technique to repair an arteriovenous fistula was able to return to work just two weeks after surgery.
Brainlab announces launch of Right.Brain Foundation
Brainlab has announced the launch of the Right.Brain Foundation, which will provide medical technology and education to selected hospitals and public institutions in Southeast Asia, Africa, Central and South America.
Advances in trigeminal nerve stimulation featured at European congress on epileptology
NeuroSigma has announced top-line summaries of presentations made at the 11th European Congress on Epileptology in Stockholm, Sweden, related to the use of external trigeminal nerve stimulation (eTNS) in epilepsy.
UK researchers take new steps towards Alzheimer’s blood test
Researchers at King's College London and co-funded by Alzheimer's Research UK have announced a panel of 10 proteins that could form a blood test to predict those most likely to develop Alzheimer's.
SMC says yes to Lemtrada 12mg IV for adults with active...
The Scottish Medicines Consortium (SMC) has published its advice that Lemtrada has been accepted for use within NHS Scotland for the treatment of adult patients with relapsing-remitting multiple sclerosis (RRMS).
Mazor Robotics receives first order for Renaissance system with brain module
Mazor Robotics has announced that it has received the first order for its Renaissance system since the commercial launch of the brain surgery module.
New results show personalised brain tumour vaccine helps patients live longer
Patients newly diagnosed with glioblastoma multiforme (GBM) and treated with an experimental cancer vaccine made from the patient’s own tumour in addition to standard of care lived longer compared to those who received standard of care alone, according to new results from a study involving Northwestern Medicine researchers and released on 1 July.
New surgical tool provides hope for patients with inoperable deep bleeding...
The Apollo system is a new surgical tool that enables minimally invasive removal of deeply seated tissue and fluids in the brain during a single, efficient operation. With combined use of an endoscope and image guidance, the Apollo system allows decompression and removal of otherwise inoperable blood clots deep in the brain, among other uses.
Omega-3 fats may significantly reduce damage from stroke
New evidence shows that the omega-3 polyunsaturated fatty acids (PUFAs) found in seafood and marine oils, DHA and EPA, can significantly reduce damage from stroke in a mouse model when given immediately afterwards.
Scotland’s National Epilepsy Centre reports 100% success rate in first year
The William Quarrier Scottish Epilepsy Centre (WQSEC), a not-for-profit partnership between charity Quarriers and the NHS, welcomed 96 patients in the 12 months after opening in April 2013, its first annual report has revealed.
Agenus brain cancer vaccine shows extended survival in phase 2 final...
Agenus has announced final results from a phase 2 study showing that patients with newly diagnosed glioblastoma multiforme (GBM) who received Agenus' Prophage autologous cancer vaccine added to the standard of care treatment, lived nearly twice as long as expected.
electroCore’s funding US$10 million oversubscribed by all parties
The final tranche of US$15 million of the US$40 million was optional but following discussions between the investors this was not only made compulsory but increased by US$10 million to a total of US$50 million.
Successful combined approach to extensive cerebral venous sinus thrombosis with Penumbra...
A combined approach with the Penumbra aspiration system (Penumbra) and the Solitaire FR retrieval device (ev3, Covidien) has been successfully used in a patient with extensive superior sagittal sinus thrombosis and cortical venous thrombosis, according to a case report.
New brain-training app Brain+ launches in the UK
Brain+, a brain-training programme that outpaces existing apps in engagement, effectiveness and economy for users, is being launched in a brand new version on the 1 July.
Lemtrada approved in Argentina for treatment of multiple sclerosis
Genzyme has announced that Argentina's National Administration of Drugs, Food and Medical Technology (ANMAT) has approved Lemtrada (alemtuzumab) for adult patients with relapsing remitting multiple sclerosis (RRMS) with active disease defined by clinical or imaging features.
FDA clears Surgical Theater’s SNAP
The Surgical Navigation Advanced Platform (SNAP) integrates with operating room technology to provide advanced 3D capabilities and augmented reality, allowing surgeons to enhance their surgery performance and "see what cannot be seen".
China to build ‘brain database’
Chinese scientists are planning to build a "brain database" in a bid to identify clues to tackling cerebral diseases and related disorders.
AHA funds new research network aimed at preventing heart disease, stroke
The American Heart Association is funding a new research network to help people make behaviour changes to prevent heart disease and stroke, the two leading causes of death in the world.
Little or poor sleep may be associated with worse brain function...
Research published in PLOS ONE by researchers at the University of Warwick, UK indicates that sleep problems are associated with worse memory and executive function in older people.
New device allows brain to bypass spinal cord and move paralysed...
For the first time ever, a paralysed man has moved his fingers and hand with his own thoughts after an electronic neural bypass for spinal cord injuries that reconnects the brain directly to muscles, allowing voluntary and functional control of a paralysed limb. This innovation comes from a partnership between The Ohio State University Wexner Medical Center and Battelle.
Lemtrada (alemtuzumab) 12mg IV, shortlisted for the 2014 Prix Galien Innovative...
Genzyme has announced that it has been shortlisted for a Prix Galien award, in the Innovative Drug Award Category, for its multiple sclerosis therapy Lemtrada.
Pilot study shows gammaCore for the prevention of migraine is safe...
The study met its endpoint of safety, and also demonstrated a reduction in the number of headache days per month for patients using the active device.
New Neuro-Oncology chair for Ohio Clinical Trials Collaborative
The Ohio Clinical Trials Collaborative (OCTC) has appointed Jill Barnholtz-Sloan as chair of its Neuro-Oncology Working Group.
Neuralstem’s NSI-189 novel neurogenic compound shows significant effect in major depressive...
Neuralstem has announced that two sets of data from the NSI-189 clinical trial in major depressive disorder were reported at two recent academic conferences: American Society of Clinical Psychopharmacology Annual Meeting, and the International College of Neuropyschopharmacology Annual Meeting.
Imperial College London initiates study to investigate genetics of Parkinson’s disease
Researchers at the Imperial College London will study individuals with genetic mutations associated with Parkinson's disease as one of 32 clinical sites of the Parkinson's Progression Markers Initiative, a large-scale biomarker study sponsored by The Michael J Fox Foundation for Parkinson's Research.
Lingraphica introduces iPad app to help survivors of stroke and traumatic...
Lingraphica has introduced the iPad app component of TalkPath Therapy, its integrated cloud-based speech therapy solution for the millions of adults with aphasia write or comprehend language, and the clinicians who work with them to improve language skills.
Neuro Resource Group’s hospital presence continues to expand
Neuro Resource Group continues to expand the utilisation of its new InterX 900 ISSDE Pain Management System for post-surgical pain management in hospitals and surgery centres.
New Philips NeuroSuite reveals the brain’s vascular network like never before
Royal Philips has announced the introduction of NeuroSuite, a new integrated solution designed to support and enhance minimally invasive image-guided neurological interventions.
Gold for Airo Mobile Intraoperative CT in 2014 Medical Design Excellence...
Airo Mobile Intraoperative CT, developed and manufactured by Mobius Imaging and distributed by Brainlab, was awarded gold in the Radiological and Electromechanical Device category of the 17th Annual Medical Design Excellence Awards (MDEA) competition.
Researchers reveal combinatorial code for the developing brain
Researchers at the Allen Institute for Brain Science have mapped the development of the mouse brain from the embryo to the adult, creating a preliminary genetic key that allows them to pinpoint the age and location of regions of the developing brain.
Study proves navigated TMS fundamentally improves treatment and outcomes for brain...
A study published in the Oxford Journal Neuro-Oncology proved that integrating navigated transcranial magnetic stimulation (nTMS) into the surgical workflow to pre-operatively localise motor function has a significant impact on treatment and outcome.
Neurim Pharmaceuticals announces publication of positive effects of add-on Circadin in...
Neurim Pharmaceuticals has announced publication of the results from an exploratory phase 2 randomised placebo-controlled clinical trial evaluating the safety and efficacy of add-on Circadin (Prolonged Release melatonin 2mg) to standard therapy in Alzheimer’s disease patients.
Foreign body retrieval could be new indication for Trevo ProVue in...
A case report has described the novel use of a stent for the removal of a foreign body from the cerebrovascular system.
New insight into how the brain regulates its blood flow
In a new study published online in the Journal of the American Heart Association, researchers at Columbia Engineering report that they have identified a new component of the biological mechanism that controls blood flow in the brain.
Floridian Community Bank supports NSU Concussion Management Clinic
Floridian Community Bank has announced that it will sponsor the Nova Southeastern University Concussion Management Clinic, one of the largest community-based sport concussion initiatives in the state of Florida.
Northwestern Medicine brings hope to patients with severe epilepsy
Specialists at Northwestern Medicine’s Comprehensive Epilepsy Center recently started using a new surgical procedure that could change the lives of epileptics who are unable to control their seizures with medication.
Vantage one-year data shows highly significant improvement in motor scores for...
Patients with Parkinson's disease treated with the Vercise deep brain stimulation system (Boston Scientific) demonstrated a highly significant and consistent improvement in motor scores, according to the latest one-year data.
Alzheon to participate in Global Dementia Legacy Meeting
Expanding on the initiatives of the G8 Dementia Summit held in December 2013, the Global Dementia Legacy Meeting will propose ways to increase and apply investments in dementia.
BrainCare promotes brain wellness after stroke and traumatic brain injury
NeuroTrax has announced the global availability of BrainCare, a cognitive assessment and report solution to aid clinicians in advancing brain wellness of stroke survivors and traumatic brain injury patients.
Parkinson’s disease trial shows that for long-term treatment levodopa is better...
For long-term treatment of newly diagnosed Parkinson's disease, the old drug levodopa provides better mobility and a higher quality of life than the two main alternatives, dopamine agonists and monoamine oxidase type B inhibitors, according to a study published in The Lancet.
Study results demonstrate advantages of Vercise
The CUSTOM-DBS clinical study demonstrated that shorter stimulation pulses may offer a clinical advantage over deep brain stimulation therapy using conventional pulses.
Brain implant offers hope for epilepsy patients
Physicians at Stanford Hospital & Clinics now offer an implantable therapeutic device, designed to detect and treat seizures, for certain patients with epilepsy.
FDA approves Apollo Onyx microcatheter
The new microcatheter is designed to mitigate the technical challenges of catheter retrieval during Onyx liquid embolic system embolisations of brain arteriovenous malformations.
Trial shows gammaCore is effective in reducing cluster headaches
In a multicentre, randomised, trial across Europe, electroCore's non-invasive vagus nerve stimulation therapy was found to meet its primary endpoint of statistical significance in reducing the number of cluster headache attacks when compared with the standard of care.
FDA approves expanded label for Azilect
The US Food and Drug Administration (FDA) has expanded the indication for Azilect (rasagiline tablets) from monotherapy and adjunct to levodopa to now include adjunct to dopamine agonists. The new indication reflects that Azilect can be used alone or in combination with other Parkinson's disease medications.
FDA IDE approval for PulseRider
The IDE allows Pulsar Vascular to begin a multicentre clinical trial in support of a humanitarian device exemption (HDE) to evaluate the PulseRider for US approval for wide neck aneurysms at or near a bifurcation of the basilar tip or carotid terminus.
MRI-guided laser procedure provides alternative to epilepsy surgery
For patients with mesial temporal lobe epilepsy (MTLE) that can't be controlled by medications, a minimally invasive laser procedure performed under MRI guidance provides a safe and effective alternative to surgery, suggests a study in the June issue of Neurosurgery.
Enterprise stent was found to be a safe and effective revascularisation...
Researchers report that in a prospective study, the Enterprise stent (Codman) was found to be a safe and effective when used for primary stenting. The findings were published in the Journal of NeuroInterventional Surgery.
USA’s first mobile stroke unit successfully transports first patient
The University of Texas Health Science Center at Houston Medical School, in partnership with Memorial Hermann-Texas Medical Center, USA, has announced that the UTHealth Mobile Stroke Unit has successfully transported and helped save the life of its very first patient.
A new approach to Alzheimer’s disease research
The Allen Institute for Brain Science, Seattle, USA, is embarking on the first effort to map connectivity patterns across the whole brain in mouse models of Alzheimer’s disease, through its recent award of a US$3.4 million grant over five years from the National Institute on Aging of the National Institutes of Health.
Breakthrough in Alzheimer’s disease: AFFiRiS halted clinical progression in Alzheimer patients...
The results of the phase II trial show an impressive therapeutic effect of AD04 and make it the first ever compound demonstrating clinical and biomarker evidence consistent with disease modification of Alzheimer's disease.
Mayo Clinic moves small-molecule drugs through blood-brain barrier
Researchers at Mayo Clinic have demonstrated in a mouse model that their recently developed synthetic peptide carrier is a potential delivery vehicle for brain cancer chemotherapy drugs and other neurological medications. The findings appear in PLOS ONE.
Clinical trial tests possible benefits of brain stimulation on hand and...
Researchers at Shepherd Center, Atlanta, USA, are studying whether stimulating the brain before rehabilitation could yield greater gains in motor function for people recovering from stroke. Researchers believe that the new approach could change common practices of care for certain stroke patients.
Constant Therapy launches iPad solution for people with traumatic brain injury,...
Designed to be used independently by anyone seeking to improve brain function or in conjunction with a clinician as an integral part of therapy, this new mobile solution integrates ground-breaking research on brain plasticity and rehabilitation from Boston University (USA) and other leading institutions.
FDA clears Night Shift therapy
Advanced Brain Monitoring has announced that the US Food and Drug Administration (FDA) has granted 510(k) clearance for Night Shift, a therapy for positional obstructive sleep apnoea.
NeuroBlate system for minimally invasive ablation of brain lesions to be...
At the biennial meeting of the American Society of Stereotactic and Functional Neurosurgery (31 May-3 June; Washington, DC, USA) Gene Barnett, director of the Rose Ella Burkhardt Brain Tumor and NeuroOncology Center at the Cleveland Clinic, will present his experience utilising NeuroBlate system (Monteris Medical) laser ablation in patients with brain tumours and radiation necrosis.
Angiochem to present positive central nervous system and peripheral anti-tumour activity...
Phase 1 and phase 2 clinical studies demonstrated promising signs of both central nervous system and peripheral anti-tumour activity of ANG1005 in patients with brain metastases including breast cancer patients.
Lemtrada resubmission accepted for review by FDA
Genzyme has announced that the US Food and Drug Administration (FDA) has accepted for review the company's resubmission of its supplemental Biologics License Application (sBLA) seeking approval of Lemtrada (alemtuzumab) for the treatment of relapsing forms of multiple sclerosis. A six-month review period has been assigned for the Lemtrada sBLA.
Symbis Surgical System named to 2014 Space Technology Hall of Fame
IMRIS has announced that the SYMBIS Surgical System - the second generation of the neuroArm / Symbis programme - is a 2014 inductee into the Space Technology Hall of Fame. The Space Foundation honour is directed at technologies originally developed for space exploration that are being transformed into products to help improve the quality of life on Earth.
Teva and Active Biotech to continue with the development of Nerventra...
Teva Pharmaceutical Industries and Active Biotech have announced that the Committee for Medicinal Products for Human Use (CHMP) confirmed its January 23, 2014 opinion to recommend against approval for the treatment of relapsing-remitting multiple sclerosis in the European Union at this time.
NICE recommends Lemtrada (alemtuzumab) 12mg IV for the treatment of active...
The National Institute for Health and Care Excellence (NICE) has issued final guidance recommending that Lemtrada should be reimbursed on the National Health Service (NHS), as an option for treating adults with active relapsing remitting multiple sclerosis.
Older migraine sufferers may have more silent brain injury
Previous studies have indicated migraine could be an important stroke risk factor for younger people. A new study published in Stroke now says that older migraine sufferers may be more likely to have silent brain injury.
Inovio Pharmaceuticals acquires early stage DNA therapies to treat Alzheimer’s and...
Inovio Pharmaceuticals has announced that it has acquired worldwide rights (excluding China) for early preclinical therapies addressing Alzheimer's disease and multiple sclerosis based on the academic research of Bin Wang, a professor at Fudan University's Shanghai Medical College.
GE Healthcare and CorTechs Labs announce strategic agreement to co-market NeuroQuant
NeuroQuant enables the acquisition of volumetric brain image data and automatically conducts accurate and consistent measurements of cortical and subcortical volumes targeted at identifying evidence of neurodegeneration. This innovative solution will provide neurologists and radiologists with objective support for their clinical impression.
FDA clears SpringTMS migraine treatment device
SpringTMS is the first medical device available to patients in the USA for the acute treatment of pain associated with migraine headache with aura. The device is currently CE marked in Europe and is available to patients in the UK.
Significant milestones set in world’s most detailed brain imaging study to...
As part of the global effort to defeat dementia, around 100,000 participants are expected to be part of the world's most comprehensive imaging project over the next five years, following the launch of a feasibility study.
Neurotrope collaborates with Paul Wender and Stanford University on bryostatin analogues
Neurotrope has signed an agreement with Stanford University to study and, along with Paul Wender, investigate certain analogs of bryostatin, referred to as "bryologs", as potential clinical candidates for the treatment of various neurological disorders.
Barnes-Jewish Hospital neurosurgeons treat 1,000th patient using VISIUS iMRI
IMRIS has announced that Barnes-Jewish Hospital in St Louis is the first US hospital to use VISIUS iMRI for more than 1,000 procedures. This clinical experience and published evidence by the neurosurgical team has shown that intraoperative MRI is an effective tool for improving results and outcomes for patients undergoing brain surgery.
Keystone heart raises US$14m in series B funding for cerebral protection...
Keystone Heart has raised US$14 million in series B funding for cerebral protection devices. By protecting all brain territories, the TriGuard cerebral protection device is designed to minimise the risk of cerebral damage during transcatheter aortic valve implantation (TAVI) and other cardiovascular procedures.
Increase in hospitalisation for subarachnoid haemorrhage also sees decline in mortality...
Tobias Pilgaard Ottosen (Department of Clinical Epidemiology, Aarhus University Hospital, Denmark), in a presentation at European Stroke Conference (Nice, France, 6-9 May) told delegates that, over a 30-year period, first-time hospitalisation for subarachnoid haemorrhage has increased.
Cooling system may have neuroprotective effects in acute stroke
A poster presented at the European Stroke Conference (6-9 May 2014, Nice, France) by Robbert-Jan van Hooff (Department of Neurology, Universitair Ziekenhuis Brussel, Brussels, Belgium) and colleagues reports that surface cooling of the neck with a surface cooling system could contribute to therapeutic hypothermia and neuroprotective effects in acute stroke.
Long-term comparative effectiveness study of VNS in patients with refractory epilepsy...
Cyberonics has announced positive results from the Pulse (Open prospective randomised long-term effectiveness) study of vagus nerve stimulation (VNS) therapy in patients with refractory epilepsy conducted at 28 sites in Europe and Canada and published in the journal Epilepsia.
Sleep researchers at SRI International identify promising new treatment for narcolepsy
Neuroscientists at SRI International have found that a form of baclofen, a drug used to treat muscle spasticity, works better at treating narcolepsy than the best drug currently available when tested in mice.
Neurosurgery chair appointed at Henry Ford Hospital
Neurosurgeon Steven N Kalkanis has been appointed chair of the Department of Neurosurgery and co-director of the Neuroscience Institute at Henry Ford Hospital in Detroit, USA.
New MRI CryoProbe delivers highest sensitivity in rat brain in vivo...
At the joint ISMRM-ESMRMB 2014 meeting (10-16 May, Milan, Italy), Bruker announced a new phased array MRI CryoProbe for in vivo neuroimaging that delivers unparalleled access to rat brain microstructure and biochemistry, previously unresolvable in in vivo imaging of the rat.
Non-drug TMS therapy shows favourable outcomes compared to oral anti-depressants
Neuronetics announced a new analysis of data at the annual meeting of the American Psychiatric Association that shows transcranial magnetic stimulation (TMS) administered with the NeuroStar TMS therapy system resulted in greater symptom improvement than next-choice conventional anti-depressant medication.
First treatment for babies with ultra-rare spectrum of autoinflammatory diseases now...
Anakinra (Kineret), an interleukin-1 (IL-1) inhibitor, is now available in the UK for treatment of CAPS in children and adults. Anakinra is the first CAPS treatment licensed for use in infants as young as eight months by the Medicines and Healthcare Products Regulatory Agency (MHRA).
Neurosurgical design nominated for business innovation award
Known as Rowena, the neurological simulator was shortlisted from over 950 entries in the FSB WorldPay UK Business Awards which take place at the Waldorf Hotel in London on 21st May. Rowena was created by consultant neurosurgeon Richard Ashpole, founder of Neurodesign.
Novel laser device used for brain surgery
Monteris Medical announced that their novel magnetic resonance imaging (MRI)-guided laser technology, the NeuroBlate system, was recently applied by neurosurgeons at UC San Diego Health System to a malignant tumour deep inside a patient's brain.
Alzheimer’s Drug Discovery Foundation raises US$1.1M for new clinical trial in...
The US$1.1 million was generated during the "Fund a Scientist" auction at its Eighth Annual Connoisseur’s Dinner on May 1, 2014, and awarded to Jeffrey Cummings, director of the Cleveland Clinic Lou Ruvo Center for Brain Health in Las Vegas, Nevada and Cleveland, Ohio, USA. Cummings will investigate rasagiline, an FDA-approved treatment for Parkinson’s disease with the potential to be the first drug to slow the course of Alzheimer’s disease.
Genzyme announces multi-year multiple sclerosis research collaboration
The research collaboration with Cleveland Clinic will be focused on developing new therapeutic approaches to the treatment of multiple sclerosis.
Two studies on the treatment of migraine headache with non-invasive vagus...
At the American Association of Neurology (AAN) meeting in Philadelphia, USA, two separate studies showed that electroCore's non-invasive vagus nerve stimulation (nVNS) therapy was effective in helping patients with different types of migraine.
Lpath lands fast-track SBIR grant from the NIH for traumatic brain...
Lpath has received official notification from the National Institutes of Neurological Diseases and Stroke (NINDS) that it has been awarded a US$1.7 million, 2.5-year grant to develop its antibody therapeutic, Lpathomab, which is directed against the bioactive lipid lysophosphatidic acid (LPA) for the treatment of traumatic brain injury.
Advance study completes enrolment for deep brain stimulation for Alzheimer’s disease
Functional Neuromodulation has completed enrolment for the Advance study. Forty-two North American patients with mild Alzheimer's have had a deep brain stimulation system implanted to evaluate the safety and potential clinical benefit of deep brain stimulation of the fornix.
Phase II study of Trimesta for relapsing-remitting multiple sclerosis yields positive...
Synthetic Biologics reports that the University of California, Los Angeles (UCLA) School of Medicine (USA) has announced preliminary, positive top-line data from the phase II clinical trial evaluating Trimesta (oral estriol), an oral, once-daily treatment for relapsing-remitting multiple sclerosis in women.
Mechanism of action of electroCore’s non-invasive vagus nerve stimulation therapy published...
In a paper published in the Journal of Pain it was reported that electroCore's non-invasive vagus nerve stimulation (nVNS) therapy can significantly reduce excessive glutamate levels in key regions of the central nervous system of animals sensitised to experience migraine-like symptoms.
Two-year study finds that vitamin E from palm oil helps to...
The results of a two-year human clinical study have been published in the American Heart Association journal, Stroke. The results show that vitamin E tocotrienols derived from Malaysian palm oil may support white matter health by weakening the progression of white matter lesions.
Study examines risk of early death for people with mild cognitive...
One of the first studies to look at a relationship between death and the two types of mild cognitive impairment suggests that people who have thinking problems but their memory is still intact might have a higher death rate in a period of six years compared to those who have no thinking or memory problems.
Lpath and Walter Reed Army Institute for Research begin efficacy study...
Lpath and scientists from the Center for Military Psychiatry and Neuroscience, Walter Reed Army Institute of Research (WRAIR), USA, have initiated a study on the use of Lpathomab, an antibody to lysophosphatidic acid (LPA), in the treatment of brain injury induced by blast overpressure.
AdvaStim enters neuromodulation device market
AdvaStim has announced that it has entered the research and development market with a new hardware/software solution for neuromodulation therapy developers.
Tampa General Hospital launches advanced intraoperative MRI use with first cases
IMRIS has announced that a University of South Florida neurosurgical team at Tampa General Hospital (TGH), USA, completed initial cases last week using its recently installed VISIUS intraoperative MRI. The first case was a right parietal high-grade glioma.
Legal safeguards needed for brain-boosting devices
Researchers from the Oxford Martin School, University of Oxford, UK, are calling for the regulation of a new breed of devices designed to enhance the brain's performance. According to Oxford Martin School, these devices, because of European legislation, only receive basic product safety requirements.
Therapies based on newly-discovered GAIM could combat neurodegenerative disorders
Researchers from NeuroPhage Pharmaceuticals have engineered a series of molecules with the potential to treat most neurodegenerative diseases that are characterised by misfolded proteins, such as Alzheimer's, Parkinson's and Huntington's diseases, according to a press release.
Carotid stenosis without warning may signal memory and thinking decline
For the first time, researchers have demonstrated that asymptomatic carotid stenosis may be linked to problems in learning, memory, thinking and decision-making, compared to people with similar risk factors but no carotid stenosis.
Study reinforces value of high-field iMRI in brain tumour resection
IMRIS has announced that a study published in the journal Neurosurgery by the neurosurgical team at Cleveland Clinic (USA) adds to growing clinical evidence which validates use of high-field intraoperative MRI (iMRI) as an effective tool for maximising the amount of surgical resection of gliomas.
Functional brain imaging reliably predicts which vegetative patients have potential to...
A functional brain imaging technique, positron emission tomography (PET), is a promising tool for determining which severely brain damaged individuals in vegetative states have the potential to recover consciousness, according to new research published in The Lancet.
Scottish Medicines Consortium approves Tecfidera for multiple sclerosis
The Scottish Medicines Consortium (SMC) has approved Tecfidera (dimethyl fumarate) as a first-line oral treatment for people with relapsing-remitting multiple sclerosis.
World’s first high-field MRI-guided radiation therapy system being installed at Dutch...
Elekta, Royal Philips and University Medical Center Utrecht (the Netherlands) announced that the initial components of the world's first high-field magnetic resonance imaging (MRI) guided radiation therapy system are being installed at University Medical Center Utrecht.
First patient enrolled in registry assessing Vercise deep brain stimulation system
Boston Scientific has enrolled the first patient in a new registry to evaluate clinical outcomes and the economic value of the Vercise deep brain stimulation system in patients with Parkinson's disease.
Covidien implements voluntary recall of its Pipeline embolisation device and Alligator...
Covidien has announced that it has notified customers of a voluntary recall to address an issue with certain lots of its Pipeline embolisation device and Alligator retrieval device where the polytetrafluoroethylene (PTFE) coating applied to the delivery wire could delaminate and detach from the devices.
CE mark approval for Airo mobile intraoperative CT
Brainlab and Mobius Imaging announced CE mark approval for Airo mobile intraoperative computed tomography. The CE mark allows Brainlab to begin installation of the systems sold in the European Union.
Monarch eTNS system receives market approval from Australian Therapeutic Goods Administration
NeuroSigma announced that it has received approval from the Therapeutic Goods Administration (TGA) to market its Monarch eTNS (external trigeminal nerve stimulation) system in Australia. The approval allows NeuroSigma to market the Monarch eTNS system for the adjunctive treatment of drug-resistant epilepsy in patients nine years of age and older.
Cognition Therapeutics receives a US patent for Alzheimer’s drug
Cognition Therapeutics has received a US patent for a drug to fight Alzheimer's disease. The patent describes the discovery of several candidate drug molecules which can stop the effects of the brain protein that appears to play a major role in development of Alzheimer’s disease.
NeuroVascular Quality Initiative launches first procedure module: Acute Ischaemic Stroke
The Society of NeuroInterventional Surgery and M2S announced the launch of the NeuroVascular Quality Initiative, a multi-module registry system designed to track performance and outcomes data across a variety of neurovascular conditions. The launch debuts the Acute Ischaemic Stroke module, which will be used to track and benchmark clinical performance at the centre level and nationally.
IMRIS iMRI and ClearPoint neuro intervention system utilised for first paediatric...
The combination of the IMRIS Visius surgical theatre and the ClearPoint neuro intervention system provided continuous real-time visualisation and guidance throughout a neurosurgical intervention to treat a brain tumour.
Antioxidant shows promise in supporting treatment for ALS
Researchers at The Center of Free Radical and Biomedical Research at Facultad de Medicina, Universidad de la Republicain Uruguay announced the discovery that the antioxidant MitoQ prolonged the lifespan and health-span of mice suffering from amyotrophic lateral sclerosis-like (ALS) disease, and successfully improved functional parameters related to muscular strength and reversed mitochondrial damage in nervous and muscle tissue.
FDA approval for Neuraceq (florbetaben F18 injection)
Neuraceq is indicated for Positron Emission Tomography (PET) imaging of the brain to estimate beta-amyloid neuritic plaque density in adult patients with cognitive impairment who are being evaluated for Alzheimer's disease and other causes of cognitive decline.
Morphology and interval growth are predictive factors of intracranial aneurysm rupture
In a study conducted by William Mehan et al, it was found that for patients with unruptured intracranial aneurysms, multilobulated morphology and interval growth of the unruptured aneurysms are "characteristics predictive of a higher risk of subsequent rupture during conservative CT angiography (CTA) follow-up."
ADAPT a safe and simple technique for ischaemic stroke thrombectomy
A direct aspiration first pass technique (ADAPT) with a large bore aspiration catheter has been shown to be "fast, safe, simple and effective method" for acute ischaemic stroke thrombectomy. The results were published in the Journal of of NeuroInterventional Surgery.
Statins slow the progression of advanced multiple sclerosis
In a two-year clinical trial involving 140 patients with secondary progressive multiple sclerosis, the drug simvastatin slowed brain shrinkage, which is thought to contribute to patients' impairments.
Prodigy spinal cord stimulation system gets CE mark approval
St Jude Medical has received CE mark approval for its Prodigy chronic pain system with burst technology, the first and only implantable neuromodulation system that delivers burst stimulation.
Functional brain imaging can provide better diagnosis and treatment monitoring in...
A new paper published by a joint US and Canadian team in PLOS One suggests SPECT (single photon emission computed tomography)-a functional brain imaging modality that produces images of blood flow to the brain, showing areas of over or under-activity-is useful in both identifying and guiding treatment for those with traumatic brain injuries.
Data from a study of PBA symptoms in veterans with mild...
Avanir Pharmaceuticals announced the presentation of results from a first-of-its-kind study of pseudobulbar affect (PBA) symptoms in veterans with mild traumatic brain injury conducted in collaboration with the Department of Veterans Affairs and Evidera.
FDA allows marketing of first medical device to prevent migraine
The US Food and Drug Administration (FDA) has approved marketing of Cefaly, the first device as a preventative treatment for migraine. This is also the first transcutaneous electrical nerve stimulation (TENS) device specifically authorised for use prior to the onset of pain.
Dartmouth-Hitchcock Medical Centre inaugurates Visius surgical theatre
IMRIS announced that neurosurgeons at Dartmouth-Hitchcock Medical Centre in Lebanon, USA, have completed several cases to inaugurate use of intraoperative MRI (iMRI) within the Visius surgical theatre inside the hospital's Centre for Surgical Innovation.
Final results of Neuralstem phase I stem cell trial in ALS...
The final results from the phase I safety trial using NSI-566 spinal cord stem cells in the treatment of amyotrophic lateral sclerosis (ALS) were published in the peer-reviewed journal, Annals of Neurology.
Stroke survivors may lose month of healthy life for 15-minute delay...
Every 15-minute delay in delivering a clot-busting drug after stroke robs survivors of about a month of disability-free life, according to a new study in the American Heart Association journal Stroke.
Blood biomarkers could help guide return to play for athletes after...
In a recent study it was found that ice hockey players in Sweden with a sports-related concussion had higher levels of the blood biomarker total tau (T-tau), which suggests the central nervous system protein may be a tool for diagnosing concussions and making decisions about when players can return to play.
Philips celebrates World Sleep Day to raise awareness of the benefits...
Philips has launched a campaign for 2014 which highlights sleep as a powerful engine for all our daily activities.
Study finds high utilisation of neuroimaging for headaches despite guidelines
A recent study has found that neuroimaging for headaches is frequently ordered by physicians during outpatient visits, despite guidelines that recommend against such routine procedures.
Significant head and neck injury risk associated with extreme sports
A new study shows that extreme sports such as snowboarding and skateboarding present high risk for head and neck injuries, including concussions. The findings support need for greater education and advocacy efforts for safer equipment.
Clinical study finds electroCore’s non-invasive vagus nerve stimulation effective in treating...
A study reported in the International Headache Society's official journal Cephalalgia found that the use of electroCore's non-invasive vagus nerve stimulation therapy may be an effective and well tolerated treatment for migraine in certain patients.
Study finds no link between football play and neurocognitive function in...
A new study presented at the 2014 Annual Meeting of the American Academy of Orthopaedic Surgeons (AAOS) found no link between neurocognitive function and years of football play in adolescent athletes.
24-month data show back and leg pain scores are reduced with...
The 24-month results of a prospective European clinical study using Nevro Corp's Senza system delivering HF10 therapy were published in the journal Pain Medicine. The study was conducted in the UK and Belgium with 65 of the 72 implanted patients (90%) being available for data collection at two years.
Enrolment begins in a second phase II study of ND0612 for...
NeuroDerm announced that enrolment of patients is ongoing in its second phase II clinical trial of ND0612, a novel drug formulation for the treatment of Parkinson's disease.
SMC says yes to Aubagio (teriflunomide)
The new once daily, first-line oral treatment can be offered as an alternative to currently available injectable treatment options for people with an active relapsing remitting form of multiple sclerosis.
Phase III GBM brain cancer trial gets recommendation to continue based...
Northwest Biotherapeutics has announced that the Data Safety Monitoring Board has made an unblinded review of the safety data for the company's ongoing international Phase III Glioblastoma multiforme (GBM) Trial, and has recommended that the trial continue as planned.
Flow diverters safe and feasible in ruptured blood blister-like aneurysms
Published in the Journal of NeuroInterventional Surgery, the results of a small study of 11 patients has demonstrated that Silk flow diverter stents (Balt Extrusion) could be a safe and feasible treatment for fragile, difficult-to-treat blood blister-like aneurysms.
Aethlon Medical and Exosome Sciences announce brain research discoveries
The brain research discoveries could have implications in the diagnosis, monitoring and treatment of Alzheimer's disease, chronic traumatic encephalopathy and traumatic brain injury.
Stroke patients treated at stem cell research centre
Stem cell research institute of STC Life and 97.7 B&H Clinic successfully completed mesenchymal stem cell treatment for stroke patients.
D-Pharm reports successful interim analysis of phase II clinical study
D-Pharm has reported the successful interim analysis of its phase II clinical study of THR-18 in acute stroke patients treated with the thrombolytic drug tPA.
US clinical site opens for expansion of CEL-SCI’s global phase III...
CEL-SCI Corporation announced its phase III head and neck cancer clinical trial of its investigational cancer immunotherapy treatment Multikine (Leukocyte Interleukin, injection) has activated its first US clinical trial expansion site at 21st Century Oncology in Greenville, North Carolina, USA.
Forest Laboratories submits new drug application for memantine extended release and...
Forest Laboratories and Adamas Pharmaceuticals announced Forest's submission of a new drug application to the US Food and Drug Administration for a fixed-dose combination of memantine HCl extended release and donepezil HCl for the treatment of moderate to severe dementia of the Alzheimer's type.
New published paper shows efficacy of Lpathomab in traumatic brain injury...
Lpath has brought scientists one step closer to finding a potential treatment for traumatic brain injury with a recent publication showing that Lpathomab, an anti-lysophosphatidic acid antibody, reverses much of the damage caused by trauma to the nervous system.
Phase I/II clinical trial for ITI-007 in healthy geriatric subjects and...
Intra-Cellular Therapies announced the initiation of ITI-007-200, a Phase I/II clinical trial designed to evaluate the safety, tolerability and pharmacokinetics of low doses of its lead drug candidate, ITI-007, in healthy geriatric subjects and in patients with dementia, including Alzheimer’s disease.
Public to get a glimpse into cutting edge brain research
University of Leicester scientists will showcase their research findings as part of Brain Awareness Day on Wednesday, 12 March
Study shows that teenagers treated for headaches were prescribed opioids almost...
Clinicians prescribed opioids for almost half of the teenagers they treated for headache when medications, such as aspirin, ibuprofen and naproxen, are recommended as first-line therapies, according to a study in the Journal of Adolescent Health.
New partnerships designed to advance Parkinson’s and dystonia care
The aim of these partnerships between Dystonia Europe and the European Parkinson's Disease Association and Boston Scientific is to increase awareness, understanding of solutions and to take initiatives in the worldwide fight against Parkinson's disease and dystonia, two areas of high unmet need.
Piramal Imaging announces EU approval of NeuraCeq
NeuraCeq (florbetaben 18F) has been approved for PET imaging of beta-amyloid neuritic plaque density in the brain.
Study shows that MS antibody may be detectable years before symptoms...
An antibody found in the blood of people with multiple sclerosis may be present long before the onset of the disease and its symptoms, according to a recent study that will be presented at the American Academy of Neurology's 66th Annual Meeting in Philadelphia, USA, April 26 to May 3, 2014.
Takeda joins the Global CEO Initiative on Alzheimer’s disease
The Global CEO Initiative (CEOi) on Alzheimer's Disease announced that Takeda Pharmaceutical Company will join the CEOi as part of its effort to spur innovations in research and accelerate a means of prevention for Alzheimer's and dementia, building momentum behind the G8's commitment to stop the disease by 2025.
Vitae earns US$14 million milestone payment from Boehringer Ingelheim in Alzheimer’s...
Vitae Pharmaceuticals announced that it has earned a US$14 million milestone payment from Boehringer Ingelheim for that company’s initiation of a Phase I clinical trial in the Vitae’s beta-secretase (BACE) inhibitor programme for Alzheimer’s disease.
Stryker launches Trevo XP ProVue retrieval system
Stryker has launched the Trevo XP ProVue retrieval system, a second generation fully visible stent retriever to treat acute ischaemic stroke.
Michael J Fox Foundation to fund the use of GlycanMap technology...
Ezose Sciences has announced that it has received a grant from the Michael J Fox Foundation for Parkinson's Research to apply Ezose's GlycanMap technology to investigating the role of the sugars known as glycans in Parkinson's disease.
STC Life successfully treats patients with Parkinson’s disease at stem cell...
The stem cell research institute of STC Life and 97.7 B&H Clinic successfully completed mesenchymal stem cell therapy for patients with Parkinson's disease.
Reverse Medical announces CE mark of UNO neurovascular embolisation system
Reverse Medical Corporation has announced the initial clinical use of their UNO neurovascular embolisation system for intracranial use. The device has been granted European Union CE mark approval to obstruct blood flow in the neurovasculature.
Clinical study focused on innovations in Parkinson’s disease biomarker discovery announced
Berg and the Parkinson's Institute and Clinical Centre has announced the next phase in their ongoing partnership, focused on identifying potential biomarkers that may lead to breakthroughs in the research, diagnosis, and treatment of Parkinson's disease.
IMRIS launches world’s first MR-safe and CT-compatible neurosurgical horseshoe headrest
The IMRIS horseshoe headrest provides non-rigid head positioning for paediatric and adult patients during brain surgery and intraoperative imaging in the VISIUS surgical theatre.
New study results demonstrate value of Cerox cerebral oxidation monitor
Ornim Medical has announced that new study results demonstrate the feasibility of the Cerox cerebral oxidation monitor for measuring regional cerebral tissue oxygenation in patients with severe traumatic brain injury.
FDA clears next generation VISIUS surgical theatre
IMRIS has announced US Food and Drug Administration (FDA) clearance of the newest generation VISIUS surgical theatre which integrates Siemens' latest high-field magnetic resonance (MR) scanners for use during neurosurgical procedures.
New stroke therapy produced significant gains in motor function post-stroke
New stroke therapy, using a combination of non-invasive navigated transcranial stimulation along with occupational therapy, has been found to produce significant gains in motor function post-stroke, with an average of 50% of stroke survivors recovering full use of their arm.
MIT professor joins Constant Therapy’s Scientific Advisory Board
Constant Therapy, a developer of a cloud-based iPad solution enabling people with cognitive, language, communication and learning disorders to access science-based brain therapies, has announced that John Gabrieli, Massachusetts Institute of Technology (MIT) Brain and Cognitive Sciences professor, has joined the company's Scientific Advisory Board.
FDA classifies worldwide voluntary correction notice on Trufill at Class I...
Codman Neuro announced that the US Food and Drug Administration (FDA) has classified the recently initiated medical device correction notice related to the Trufill n-BCA liquid embolic system as a Class I recall.
Intracranial carotid artery atherosclerosis associated with increased stroke risk
A build-up of plaque in the carotid artery above the neck was associated with an increased risk of stroke for older white patients in a recent study.
InspireMD reports successful implantation of the new CGuard carotid embolic system...
InspireMD has announced that its new CGuard carotid embolic protection system, designed to trap the debris that can travel downstream after a patient is treated with traditional stenting methods, has been successfully implanted in recent procedures.
Brain Research Foundation announces 2014 Scientific Innovations Awards
The Brain Research Foundation has announced the 2014 Scientific Innovations Awards to fund ground-breaking work in Parkinson's disease, epilepsy, Hurler syndrome and autism.
MRI increases the incidence of extra-axial intracranial tumour diagnosis
A Norwegian study has found that cerebral, regional magnetic resonance imaging (MRI) can lead to an increase in incidence rates of intracranial tumour diagnosis.
Vilcek Foundation honours renowned neuroscientist
British-born neuroscientist honoured by Vilcek Foundation.
The ALS Association announces new grants to investigate the causes of...
Five new grants have been awarded to investigate the causes of and treatments for amyotrophic lateral sclerosis
Tecfidera approved in the European Union as a first-line oral treatment...
The European Commission has approved Tecfidera (dimethyl fumarate) as a first-line oral treatment for multiple sclerosis.
US dementia experts to share best practices in phase III clinical...
A US team of dementia experts will visit Russia to share experiences in phase III clinical research study.
BrainStorm signs definitive agreement with Mayo Clinic for ALS clinical trial
BrainStorm Cell Therapeutics has signed a definitive agreement with the Mayo Clinic to conduct Phase II of its ALS clinical trial.
Stenting without post-dilation is a safe and feasible strategy in the...
The results of a study published in the Journal of NeuroInterventional Surgery have shown that carotid stenting without post-dilation is safe and effective.
Myelin Repair Foundation and NIH enter into agreement to repurpose MRF-008...
The Myelin Repair Foundation has announced that it has entered a Cooperative Research and Development Agreement (CRADA) with the National Institutes of Health (NIH) to assess MRF-008, as a potential therapeutic for multiple sclerosis. The NIH are expect to instigate a clinical trial to assess this.
Canadian collaboration to fund anti-hypertensive drugs for Alzheimer’s disease research
A new funding collaboration to support a clinical trial investigating the potential for hypertension drugs to slow Alzheimer's disease progression has been announced between The Alzheimer's Drug Discovery Foundation of Canada and The W Garfield Weston Foundation.
Positive clinical performance of MS Precise for multiple sclerosis reported
New data has been reported supporting the clinical validation of MS Precise (DioGenix), a next-generation sequencing assay for the identification of patients with multiple sclerosis at first clinical presentation.
eNeura files 510(k) with the FDA for SpringTMS migraine treatment
eNeura has reported that it has filed a 510(k) with the US Food and Drug Administration (FDA) for the SpringTMS transcranial magnetic stimulation (TMS) device. SpringTMS is CE marked in Europe and available by prescription in the UK.
Brain surgeon teams with NASA scientists to develop 3D high-definition surgical...
Brain surgeon Hrayr Shahinian (the Skull Base Institute, Los Angeles, USA), a pioneer in minimally invasive surgery, and NASA's Jet Propulsion Laboratory in Pasadena, USA, have introduced the next generation of high-tech surgical instruments to remove tumours and treat other brain abnormalities.
Take head injuries seriously, says NICE
Time is of the essence when treating head injuries to avoid potentially serious complications, including disability or death, says the National Institute for Health and Care Excellence (NICE). Its updated guidance on the issue emphasises the importance of early detection and prompt treatment for both children and adults who have suffered trauma to the head.
Kessler Foundation neuroimaging study sheds light on mechanisms of cognitive fatigue...
The study, published in PlosOne, is the first study to use neuroimaging to investigate aspects of cognitive fatigue. The findings of the study support the part that the striato-thalamic-frontal cortical system plays in fatigue, suggesting a "fatigue-network" in multiple sclerosis.
Transcranial magnetic stimulation a “breakthrough treatment” for migraine patients
In NHS guidance, the National Institute for Health and Care Excellence (NICE) has announced the results from clinical trials investigating a portable transcranial magnetic device for the treatment of migraine.
NICE recommends Aubagio for multiple sclerosis
In final guidance, the National Institute for Health and Care Excellence (NICE) has recommended the use of Genzyme's multiple sclerosis drug teriflunomide (also called Aubagio) for adults with relapsing-remitting multiple sclerosis.
Middle-school girls continue to play football with concussion symptoms, study finds
Concussions are common among middle-school girls who play soccer, and most continue to play with symptoms, according to a study published in JAMA Pediatrics and by John W O' Kane, University of Washington Sports Medicine Clinic, Seattle, USA, and colleagues.
Vitamin D status associated with multiple sclerosis activity and progression
Vitamin D status appears to be associated with reduced disease activity in patients with multiple sclerosis and a slower rate of disease progression, according to a study by Alberto Ascherio, Harvard School of Public Health, Boston, USA, and colleagues.
Journal of the International Neuropsychological Society announces new editor-in-chief
Stephen M Rao has been named the new editor-in-chief of the Journal of the International Neuropsychological Society (JINS). Rao is the pioneer of the application of task-activated MRI and has applied this strategy to brain mapping for neurodegenerative conditions.
Richard Hammond backs children’s brain injury book launch
Top Gear presenter Richard Hammond is backing the launch of a book launch aimed at helping youngsters and their parents to better understand brain injuries and their hidden effects, it was reported in a press release from the Children's Trust.
Research confirms effectiveness of Cognigram, a new test for Alzheimer’s disease
A study from Australia, published online first in BMC Psychology, has confirmed the effectiveness a new test for Alzheimer's disease. The test is said to detect cognitive decline in patients by scoring attention/reaction and learning/memory and comparing the scores to traditional cognitive impairment indicators.
Stryker and NeuroLogica partner to provide surgical navigation with the BodyTom...
Stryker and NeuroLogica have announced an exclusive partnership agreement in which Stryker will promote and sell NeuroLogica's BodyTom portable full-body computed tomography (CT) scanner for the specialties of neurosurgery, spine surgery, orthopaedic surgery, and trauma surgery in conjunction with the Stryker NAV3i surgical navigation platform.
13,000 patients treated with Visius surgical theatre since 2005, study indicates
Results of an internal study of 40 worldwide Visius surgical theatre hospital customers indicates that nearly 13,000 patients have been treated using intraoperative MRI (iMRI) since the first installation in 2005.
National stroke summit tour to bring physicians across the USA together...
The Society of NeuroInterventional Surgery (SNIS) on 9 January has launched a 2014 national tour that will bring together physicians and medical personnel across the USA involved in stroke care to address current stroke treatment and the value of neurointerventional therapy in optimal stroke care delivery.
Next Wave brain stimulation for neuro-ophthalmologic patients available at German University
University Medical Center Hamburg-Eppendorf, Germany, is now offering the use of the EBS Next Wave brain stimulation device designed to expand the visual field of patients with impaired vision caused by optic nerve damage, it was announced by EBS Technologies.
Oscar 2 selected by PRA for pharmaceutical research trial for Alzheimer’s...
The SunTech Medical Oscar 2 ambulatory blood pressure monitoring system has been selected by PRA for use in a phase I clinical study. The study will investigate the inhibition of degenerative mechanisms to provide improved neuroprotection for those with Alzheimer's disease.
Device used to assess elevated brain pressure could benefit astronauts
A clinical research study of a non-invasive intracranial pressure measurement device has been launched by the National Space Biomedical Research Institute (NSBRI) and Vittamed, the developer of the device. The study will include the monitoring of neurological patients, as a prelude to possible future use with astronauts.
Apeiron signs regional license agreements for the commercialisation of a neuroblastoma...
Apeiron has announced the signing of two transactions as part of the worldwide commercialisation of APN311, an antibody-based immunotherapy in development for the treatment of children suffering from high-risk neuroblastoma.
Parkinson’s research study shows inosine compound raises urate levels
New findings published in JAMA Neurology from research into a potentially protective therapy for Parkinson's disease show that with medical supervision, urate levels may safely be raised while mitigating risk of complications such as gout. Previous research showed that higher levels of the antioxidant urate were associated with lower risk and slower progression of the disease.
BioCrea wins the Epilepsy Innovation Seal of Excellence Award
BioCrea announced on 9 January that the Epilepsy Foundation (USA) has presented the Epilepsy Innovation Seal of Excellence Award to BioCrea in recognition of the creation of the new anti-seizure platform, GABAA PAMs (LT GABAA PAM), to treat refractory epilepsy.
TauRx expands Alzheimer’s clinical trials in the USA
TauRx Therapeutics has expanded its international clinical trials by adding new research centres across the USA. The company says the addition of 35 clinical research centres means that more patients suffering from mild or moderate Alzheimer’s, and their caregivers, will have an opportunity to see if they qualify for participation in TauRx’s Alzheimer’s clinical trials.
Cognitive function in combat veterans with repeated brain injury examined
Researchers at Albert Einstein College of Medicine of Yeshiva University, New York, USA, in cooperation with Resurrecting Lives Foundation, are investigating the effect of repeated combat-related blast exposures on the brains of veterans.
First patient treated in Neuralstem China stem cell trial to treat...
The first patient was treated in the phase I/II NSI-566 stem cell trial to treat motor deficits from ischaemic stroke at BaYi Brain Hospital in Beijing, China, according to a press release.
Anxiety linked to higher long-term risk of stroke
A new study published in Stroke has identified that there is a higher risk of stroke in people with high levels of anxiety.
Implant allows rats with brain damage to rapidly recover motor skills
Scientists at the University of Kansas School of Medicine and Case Western Reserve University have developed a lightweight, battery-powered device that appears capable of repairing damaged pathways in the brain. The technology holds promise helping individuals who suffer from the damage left by stroke or head injuries.
Cerena TMS device for migraine headache pain gets FDA approval
The Cerena Transcranial Magnetic Stimulator (TMS) from eNeura Therapeutics is a prescription device used after the onset of pain associated with migraine headaches preceded by an aura.
Falls in Parkinson’s disease may be adversely impacted by deep brain...
New findings from the Parkinson Alliance show that falls are highly prevalent in Parkinson's disease and may be adversely impacted by deep brain stimulation therapy.
G8 countries agree to find a cure and treat dementia by...
Alzheimer’s Association president and CEO Harry Johns presented and participated in the first ever G8 Dementia Summit hosted by the UK. World leaders acknowledged that the Alzheimer’s and dementia crisis cannot be ignored. All of the G8 countries committed to the goal of identifying disease-modifying therapies or a cure for dementia by 2025.
Preliminary findings of phase IIa study of NurOwn reported as “extremely...
BrainStorm Cell Therapeutics has announced that the preliminary findings from the ongoing phase IIa dose-escalating trial evaluating NurOwn technology was presented at the 24th International Symposium on ALS/MND in Milan, Italy.
Clinical study of selective muscarinic M1 receptor agonist for Alzheimer’s disease...
Heptares Therapeutics has announced that it has initiated a phase I clinical study of HTL9936, the first fully-selective muscarinic M1 receptor agonist to enter clinical development. HTL9936 is an orally available, small molecule drug candidate using the Heptares GPCR structure-based drug-design (SBDD) platform.
US stroke deaths declining due to improved prevention and treatment
Stroke deaths in the USA have declined dramatically in recent decades due to improved treatment and prevention, according to a statement published in Stroke.
ALS Therapy Development Institute and Neurimmune partner to advance treatments for...
The ALS Therapy Development Institute (ALS TDI) and Anelixis Therapeutics have announced that it has formed a research partnership with Neurimmune to advance potential treatments for amyotrophic lateral sclerosis (ALS).
Thirty patients implanted in Advance study of deep brain stimulation for...
On 5 December, the company Functional Neuromodulation reported that 30 patients with mild Alzheimer's disease have been successfully implanted in the ongoing Advance study.
MRI Interventions and Imris technologies combine to lessen anxiety for deep...
Imris and MRI Interventions announced that Cook Children's Medical Center in Fort Worth, USA, is the first US paediatric hospital to offer asleep deep brain stimulation surgery to children suffering from dystonia by utilising the combination of MRI Interventions' ClearPoint Neuro Intervention System and an Imris Visius Surgical Theatre for real-time intraoperative image guidance and procedure visualisation.
First US implants of new Medtronic deep brain stimulation system
The first US implants of a novel deep brain stimulation system in research that is investigating the brain's response to the therapy has been announced by Medtronic.
Telemedicine can bring Parkinson’s care to “anyone, anywhere”
A new study shows that a neurologist in an office thousands of miles away can deliver effective specialised care to people with Parkinson's disease. For patients with the condition, these "virtual house calls" could allow them to live independently while effectively managing the symptoms of the disease.
Study of Prodigy neurostimulator to evaluate burst stimulation technology for chronic...
St Jude Medical has initiated a clinical study of the Prodigy neurostimulator, the first spinal cord stimulation system able to deliver a proprietary mode of stimulation therapy called burst stimulation. The study will evaluate whether burst stimulation can be more effective in managing chronic pain than traditional tonic stimulation.
Mechanical thrombectomy is beneficial if implemented by a collaborative neurointerventional team
A presentation at ESMINT (5-8 September, Nice, France) says that there are studies that indicate the benefit of mechanical thrombectomy if it is performed with a collaborative team of interventional neuroradiologists, neurologists and neurosurgeons and in dedicated stroke centres. Read more
Favourable results for real-world experience with the Precision Spectra Spinal Cord...
New retrospective data highlighting the Precision Spectra Spinal Cord Stimulator (Boston Scientific) System demonstrate the device provided highly significant pain relief three months after implantation. The results were presented at the North American Neuromodulation Society (NANS) 17th annual meeting in Las Vegas, USA (5-8 December).
Electrosonic stimulation as adjunctive therapy shows “significant improvements” in Parkinson’s disease...
A presentation on electrosonic stimulation as adjunctive therapy to dopaminergic treatments at the 5th International Symposium on Neuromodulation says that patients undergoing stimulation with the ESStim technology (Highland Instruments) saw significant improvements relative to baseline measurements when compared to sham stimulation in Parkinson's disease patients.
Novel rehabilitation device improves motor skills after stroke
Using a novel stroke rehabilitation device that converts an individual's thoughts to electrical impulses to move upper extremities has reported improvements in stroke patients' motor function and ability to perform day-to-day activities. Results of the study were presented at the annual meeting of the Radiological Society of North America (RSNA; 1-6 December, Chicago, USA).
Health Canada approves Aubagio for relapsing remitting multiple sclerosis
Genzyme has announced that Health Canada has approved Aubagio (teriflunomide) 14mg as monotherapy for the treatment of patients with relapsing remitting multiple sclerosis (RRMS) to reduce the frequency of clinical exacerbations and to delay the accumulation of physical disability.