Tag: acute ischaemic stroke

Following Basking Biosciences’ recent announcement that the first acute ischaemic stroke patients have received its novel thrombolytic therapy as part of the Phase 2...

TargED Biopharmaceuticals has today announced that it has commenced clinical development with the dosing of the first participant with TGD001—a “groundbreaking” thrombolytic designed to...

“The race is on—don’t miss the bus!”, were the words of David Liebeskind (University of California Los Angeles Health, Los Angeles, USA) as he...

Data from a registry claimed to be the first prospective registry on mechanical thrombectomy for stroke in India have revealed a number of key...

A systematic review and meta-analysis of five studies and more than 11,000 patient records has indicated that each hour saved between acute ischaemic stroke...

Prolong Pharmaceuticals has announced that its investigational therapy—PEGylated carboxyhemoglobin, bovine (PP-007)—has received a fast-track designation from the US Food and Drug Administration (FDA) for...

Remedy Pharmaceuticals has announced that the US Food and Drug Administration (FDA) Office of Orphan Products Division (OOPD) has granted orphan drug designation to...

The European Stroke Organisation (ESO) Executive Committee’s Thrombolysis Taskforce has provided “important updates” regarding the security of supply for Metalyse (tenecteplase) and Actilyse (alteplase)...

Following the recent publication in Stroke: Vascular and Interventional Neurology of results from HEMERA-1, a prospective, multicentre trial evaluating the safety of novel neuroprotective...

This year’s European Stroke Organisation Conference (ESOC; 15–17 May, Basel, Switzerland) saw a plethora of data on intravenous tenecteplase—from studies spanning Australia, Canada, China,...

Today, Penumbra announced the launch of its Midway 43 and Midway 62 delivery catheters, which are designed to provide ideal tracking and a stable...

Cerenovus, part of Johnson & Johnson MedTech, has today announced the launch of its Cereglide 71 aspiration catheter in Europe, an aspiration catheter equipped...

An analysis involving some 300 patients with anterior-circulation acute ischaemic strokes caused by tandem lesions has determined a number of factors that may be...

In a guest article for NeuroNews, Adnan Mujanovic (Bern, Switzerland) discusses a relatively unknown but potentially significant factor in stroke patients experiencing poor clinical...

One-year follow-up data from two randomised controlled trials (RCTs) evaluating mechanical thrombectomy in patients with ischaemic strokes caused by large-core infarct volumes have demonstrated...

NOTE: This video is ONLY available to watch in selected countries and geographies  Interventional neuroradiologists Vincent Costalat (University Hospital of Montpellier, Montpellier, France) and...

Basking Biosciences has announced the close of US$55 million in financing, which will be used to accelerate clinical development of its novel thrombolytic therapy...

In light of recent evidence indicating that thrombectomies with poor reperfusion may lead to inferior clinical outcomes versus medical management in ischaemic stroke, Adrien...

Conrad Yiu, a pioneer and visionary in interventional ischaemic stroke therapy, passed away in the final weeks of 2023, succumbing to the very disease for...

A “historical milestone” for stroke patients in Brazil was achieved recently, with the country’s Ministry of Health (MOH) publishing Order 1.996/2023 on 24 November...

Perfuze has announced commencement of enrolment in its pivotal MARRS study—a multicentre trial set to evaluate the performance of aspiration thrombectomy with the company’s...

Athersys has announced that the independent data safety monitoring board (DSMB) has completed a preplanned interim analysis of the company’s ongoing, phase three MASTERS-2...

iVascular has announced that the SEMTIC study, evaluating the safety and efficacy of its comprehensive stroke thrombectomy treatment, is one step closer to providing...

Despite having worse stroke symptoms and living within comparable distances to comprehensive stroke centres (CSCs), women with large vessel occlusion (LVO) acute ischaemic stroke...

Highly targeted electrical stimulation to the brain has shown promise as a treatment option for acute ischaemic stroke, according to a pilot study led by University...

As per a press release from AptaTargets, JAMA Neurology has published positive results from APRIL—a Phase 1b/2a clinical trial evaluating the safety and efficacy...

A new study conducted by scientists at Louisiana State University (LSU) Health New Orleans Neuroscience Center of Excellence (New Orleans, USA) reports that the...

New data from the VECTOR randomised controlled trial—presented at the European Stroke Organisation Conference (ESOC; 24–26 May, Munich, Germany)—have indicated that a mechanical thrombectomy...

As per results from the RESIST study, remote ischaemic conditioning (RIC)—while not being associated with any major safety issues—has failed to improve functional outcomes...

Endovascular therapy (EVT) has been deemed safe and effective in patients with ischaemic stroke caused by an anterior circulation large-vessel occlusion (LVO) who present...

MIVI Neuroscience has announced that it has completed enrolment in the EVAQ clinical trial to assess the safety and effectiveness of the Q revascularisation system...

Intravenous tenecteplase was associated with a higher rate of intracranial haemorrhage (ICH), as compared to alteplase, in a recent analysis of real-world data from...

While a number of companies in the neurovascular space have become increasingly focused on the ‘first-pass effect’ in mechanical thrombectomy treatments, many major clinical...

Phenox, a Wallaby Medical company, has announced the US Food and Drug Administration (FDA) 510(k) clearance of its Preset thrombectomy device for the treatment...

ApTOLL, a neuroprotectant medication intended to shield the brain from tissue damage, has been linked to reduced death and disability when used alongside standard...

A meta-analysis of recent basilar artery occlusion trials—including ATTENTION and BAOCHE—has further indicated the potential benefits held by endovascular therapy (EVT) in treating posterior-circulation...

Basking Biosciences has announced that it will be presenting three oral presentations and two moderated posters concerning the company’s novel drug candidate—a reversible thrombolytic...

A systematic review of interventional acute ischaemic stroke treatments in Latin American countries has found that mechanical thrombectomy usage in these regions is “comparable...

The “renaissance” of neuro- and cerebroprotective paradigms, coupled with “the advent of new ideas”—such as the concept of ‘transient neuroprotection’ to preserve the penumbra—appears...

The thrombolysis taskforce of the European Stroke Organisation (ESO) executive committee has provided an update on current shortages of alteplase and tenecteplase, detailing outcomes...

A wealth of new data confirming the beneficial role mechanical thrombectomy can play in the treatment of acute ischaemic stroke came to light through...

Following the publication of a case report in Topics in Magnetic Resonance Imaging, researchers from Malaysia have indicated that the use of vessel-wall imaging...

Penumbra announced today that its RED reperfusion catheters have secured a CE mark and are now commercially available in Europe. The catheters are part of...

Penumbra today announced initial INSIGHT registry data showing that its RED reperfusion catheters were successful in removing all clot types—and, additionally, results of sub-analyses...

Route 92 Medical recently announced the publication of an investigator-initiated, multicentre SLIC (Super large-bore ingestion of clot) study of its proprietary Monopoint operating platform,...

NeuroVasc Technologies recently announced that the first patient has been treated in its US investigational device exemption (IDE) clinical study, the ENVI randomised controlled...

In what is claimed to be the largest stroke clinical trial ever run in Canada, researchers have shown that tenecteplase—a safe, well-tolerated drug commonly...

In December 2021, University Hospital Basel (Basel, Switzerland) enrolled the first patient worldwide in the DISTAL study—a multicentre randomised controlled trial (RCT) evaluating the...

Vesalio has announced the completion of patient enrolment for the CLEAR US Food and Drug Administration (FDA) investigational device exemption (IDE) study utilising the NeVa...

Microvention, a wholly owned subsidiary of Terumo Corporation, has announced the successful completion of its first patient enrolment in a multicentre, prospective, observational study...

When comparing outcomes for acute ischaemic stroke patients treated at various levels of stroke centres, patients who received care at comprehensive stroke centres (CSC) or thrombectomy-capable...

In a phase 2a clinical trial in China, the clot-busting medication tenecteplase has been shown to be effective in restoring blood flow to the...

Cerenovus—a neurovascular firm that forms part of Johnson & Johnson Medical Devices Companies—has announced the launch of Emboguard, its next-generation balloon guide catheter to...

Perfuze announced today that it has closed a €22.5 million Series A investment round—the proceeds from which will be used to drive the next...

The American Academy of Neurology (AAN) has issued a position statement for neurologists on how to navigate consent issues for people who have experienced acute ischaemic...

Artificial intelligence (AI) and the role it can play in improving acute ischaemic stroke care protocols took centre stage at the Barts Research and...

Phenox has added to its extensive technology portfolio with the introduction of the pRESET 6-50 mechanical thrombectomy device for the treatment of acute large...

North Carolina has updated its emergency stroke care protocol—a move applauded by the Get Ahead of Stroke campaign. The protocol, which went into effect...

NeuroVasc Technologies has announced that the first patient has been treated in a pivotal randomised controlled trial (RCT) in China, which will evaluate the...

At this year’s LINNC Paris Course (14–16 September, Paris, France and virtual), audiences heard that the ESCAPE-NEXT trial (sponsored by NoNO Inc.), which has already started enrolling...

Sensome has announced enrolment of the first patients in the multicentre, first-in-human CLOT OUT study, which will evaluate the safety and performance of the...

In a pilot programme in New York City, USA, a mobile interventional stroke team (MIST) travelled directly to patients to perform emergency stroke surgery...

Using a different type of computed tomography (CT) scan may reduce the time to essential surgery for patients with the deadliest kind of strokes—emergent...

Repeated clot retrieval attempts are associated with an increased rate of emboli to new territory (ENT) and greater infarct growth—resulting in poorer functional outcomes...

Penumbra has announced US Food and Drug Administration (FDA) 510(k) clearance and commercial availability of the RED 62 reperfusion catheter—the latest addition to the...

Vesalio has successfully secured a Class A financing round. The company claims this funding will be utilised to support its ongoing US Investigational Device...

HeMo Bioengineering, a Singapore-based medical device company with a focus on treating stroke patients, has announced that its Afentta intracranial thrombectomy aspiration catheter—a product...

The noninferiority of mechanical thrombectomy alone—compared to mechanical thrombectomy plus intravenous tissue plasminogen activator (IV-tPA)—for the treatment of acute ischaemic stroke has been demonstrated...

US medical device company Vesalio has announced the start of enrolment in the Vesalio CLEAR study—an acute ischaemic stroke FDA investigational device exemption (IDE)...

A recent Cerenovus study published in the Journal of Stroke (JOS) has found that in the treatment of acute ischaemic stroke, achieving complete or near...

A study published in Stroke reviewing nearly 28,000 emergency department records across 54 healthcare facilities has shown that less than 2% of patients diagnosed with COVID-19 suffered...

Ching-Jen Chen discusses his recent publication in the BMJ entitled, “Is a picture-perfect thrombectomy necessary in acute ischaemic stroke?” Whether imaging findings translate into outcomes...

A study recently published in the BMJ reports no observed delay in the treatment of patients with intracranial occlusion with endovascular thrombectomy (EVT) during the...

A study published in the online issue of Neurology has found that people aged 70 and older are having fewer strokes and are also...

Vesalio has announced in a company press release that it has received 510(k) clearance from the US Food and Drug Administration (FDA) and its...

Biomodex has announced its partnership with two of the top medical centres in France and a health system in the USA to develop Evias...

A new study has found several racial disparities after mechanical thrombectomy for stroke with respect to post-procedure management and outcomes. Vineeth Thirunavu of Northwestern...

Rapid Medical has announced CE mark approval for Tigertriever XL stentriever. The company noted that the first patients have been treated successfully with the...

The Society of NeuroInterventional Surgery (SNIS) has published a set of recommendations for the care of emergent neurointerventional patients during the COVID-19 pandemic. “Acute...

A new, non-invasive wearable magnetic brain stimulation device to improve recovery for stroke survivors has been deemed safe and effective. David Chiu, director of...

Thrombolytic Science (TSI) has announced progress with 10 patients enrolled in its prospective, randomised, multicentre phase 2 clinical trial, designed to confirm the safety...

According to Laura Stein and others from the Icahn School of Medicine at Mount Sinai, New York, USA, patients admitted with acute ischaemic stroke...

A progressive emergency medical services (EMS)–driven partnership in South Florida (USA) has expedited access to lifesaving care for stroke patients. This groundbreaking effort to...

Perfuze, a medical device company developing next-generation catheter-based technology to treat acute ischemic stroke, has been granted breakthrough device designation by the US Food...

A topical review published in Stroke investigates new approaches for the collection of outcomes data after stroke. In the context of global technological growth,...

Acandis GmbH announces that it has received European CE mark approval for its APERIO hybrid thrombectomy device. APERIO is intended for restoration of the...

A study in which ambulance paramedics treated patients suspected of having an acute stroke with transdermal glyceryl trinitrate (GTN) to lower their blood pressure...

Insera Therapeutics has announced that it has received CE mark approval for its flagship product, the CLEAR Aspiration System, for the aspiration of blood...

The relationship between blood pressure and outcomes is highly dependent on reperfusion, conclude Lang Hong (Fudan University, Shanghai, China) and colleagues on behalf of...

In a subgroup of acute ischaemic stroke patients presenting with Alberta stroke program early CT score (ASPECTS) 0–5, who were treated with mechanical thrombectomy,...

iSchemaView receives approval from ANVISA (the Brazilian Health Regulatory Agency), for the use of the RAPID imaging platform across Brazil. RAPID is designed to...

Real-world data investigating patient outcome after endovascular stroke therapy in high versus low volume centres finds a 30% increase in the likelihood of a...

  Intensive glucose control (80–130mg/dL) does not improve 90-day functional outcome and increases the risk of severe hypoglycaemia. This is the conclusion presented by Karen...

The fact that endovascular therapy is now well established for patients with acute ischaemic stroke has changed the face of stroke treatment forever. The last five...

A series of studies published in the Journal of NeuroInterventional Surgery is bringing attention to potential constraints in the practice-changing DAWN and DEFUSE 3 trials, when...

Amid the current modernisation of ischaemic stroke treatment, Michael Chen discusses how telemedicine not only has tremendous value, but should become a more standard...

Enabling more clinicians to assess cerebral blood flow characteristics and detect neurological diseases such as stroke using robotic ultrasound technology could help to facilitate...

Thrombectomy is a highly effective way to treat ischaemic large vessel occlusion stroke. “Time is brain” remains crucial as the thrombectomy benefit is highly...

Addressing the diverse unmet clinical and environmental needs is crucial in reducing the high level of disabilities and stroke recurrence that currently characterise the...

In patients with unknown symptom onset stroke with MRI pattern of DWI-FLAIR-mismatch, treatment with alteplase resulted in better functional outcome than placebo. These benefits...

The first patients have been enrolled in the TIGER (Treatment with Intent to Generate Reperfusion) study. This is a multicentre study of the performance...

iSchemaView has received final clearance from the US Food and Drug Administration (FDA) for RAPID CTA, the company’s 3D imaging solution for Computed Tomography...

The study results show that endovascular therapy, given alongside standard medical therapy, results in better functional outcome than standard medical therapy alone for ischaemic...

Advertorial Health services across Europe have now implemented new policies to sustain the development of thrombectomy procedures. England’s National Health Service (NHS England) has made...

Oral contraceptives increase the risk of ischaemic stroke, but this risk is very small among women who do not have other stroke risk factors,...

EmboTrap (Neuravi/Johnson and Johnson’s Cerenovus) achieved a high reperfusion rate among acute ischaemic stroke patients with large vessel occlusion. With three, or fewer, passes...

In this educational supplement we focus on ischaemic stroke. We look at the results of the ASTER trial and experts weigh in on the...

Advertorial An interventional neuroradiology team has recorded significant improvement in time-to-treat in acute ischaemic stroke patients treated with mechanical thrombectomy over a five-year period. The...

With the results of the DAWN trial now published in the New England Journal of Medicine and the late time window data from the...

The real-life use of the EmboTrap device (Neuravi/Cerenovus) has provided “very good outcomes” when compared to that observed in large mechanical thrombectomy trials which...

According to one presentation given at the Society of NeuroInterventional Surgery’s 14th Annual Meeting (SNIS; 24–27 July, Colorado Springs, USA) the 3D revascularisation device...

John Muir Health’s Walnut Creek Medical Center, Walnut Creek, USA, has been awarded Comprehensive Stroke Certification Accreditation by The Joint Commission, which accredits and...

Despite prevention efforts, researchers have found a significant increase over a 10-year period in the percentage of people with stroke who have high blood...

Stroke experts from across Europe gathered in Brussels under the umbrella of the European Stroke Organisation (ESO) to call on political leaders to recognise...

One New York City-based centre is projecting that door-to-puncture times for the endovascular treatment of acute ischaemic stroke patients can be reduced to as...

  The first patient has been enrolled in the TIGERTRIEVR registry at the Cantonal Hospital of Lucerne, Switzerland. The Tigertriever (Rapid Medical) is a one-of-a-kind, fully-visible,...

Following an interim analysis of data from the first 182 patients enrolled in DEFUSE 3, the trial has been terminated and is no longer...

A new study from Barcelona has shown that in a subgroup of patients, direct transfer and triage in the angiosuite seems feasible, safe, and achieves significant...

A new scoring method may help predict who is at high risk of serious bleeding after a stroke, according to a study published in...

In the USA, less than half of stroke patients discharged from the hospital received a prescription for statins, and the likelihood of a prescription varied...

Stroke patients who stopped taking statin drugs three to six months after a first ischaemic stroke had a higher risk of a having another stroke...

The results of the VITAL study demonstrate that a non-invasive, visor-like neurological device (VIPS technology from Cerebrotech Medical Systems) can identify those patients with...

In a study published in the journal Stroke, Lorenzo Rinaldo and colleagues from the Mayo Clinic, Rochester, USA, have reported that transfer of acute...

A subanalysis from the SWIFT PRIME trial has found that time to randomisation was significantly longer in magnetic resonance imaging (MRI)-selected patients in the...

The DAWN trial results, presented at the European Stroke Organisation Conference (ESOC) by Tudor Jovin and Raul Nogueira, dramatically change the landscape for treatment...

The much-anticipated results from the DAWN trial were finally revealed at the European Stroke Organisation Conference (ESOC; 16–18 May, Prague, Czech Republic) strongly indicating...

A study published online by JAMA Neurology has found that when a specific primary stroke centre protocol was fully executed in the treatment of...

Data from the pooled analysis of the HERMES collaboration have shown that stroke patients given endovascular treatment under general anaesthesia experienced worse outcomes than...

A new article published by JAMA Neurology examines acute stroke hospitalisation rates in younger adults aged 18 to 64 years by stroke type and...

A new process, developed by the American Heart Association/ American Stroke Association, will help streamline the initial emergency care of stroke patients. The new Severity-based...

Interventions in the aorta and manipulations in the aortic arch have become a “potential source of embolisation to the brain,” notes Roger Greenhalgh, Chairman...

Perflow Medical has announced the issuance of US Patent No. 9510855, by the US Patent and Trademark Office (USPTO), for the Stream Dynamic Neuro-Thrombectomy...

An early end to patient enrolment in the DAWN trial has been activated following a pre-planned interim analysis of the data from the first...

The European Stroke Organisation (ESO), together with the European Society of Minimally Invasive Neurological Therapy (ESMINT) and the European Society of Neuroradiology (ESNR), endorsed...

The primary results of the ASTER randomised controlled trial (RCT) have shown no statistically significant difference between ADAPT (a direct aspiration first pass technique)...

Enrolment is now complete in the ARISE II clinical trial which is assessing the safety and effectiveness of the EmboTrap II revascularisation device (Neuravi),...

In 2016, Penumbra announced the launch of the ACE68 reperfusion catheter, part of the Penumbra System at the Society of NeuroInterventional Surgery 13th Annual...

As the number of patients eligible for endovascular treatment of acute ischaemic stroke increases, centres across Europe must consider whether there are enough interventionalists...

Amnis Therapeutics has received approval to perform a first-in-human clinical trial with its neuro thrombectomy device, the Golden Retriever. The approval was received from...

Comparing the outcomes on computed tomography (CT) perfusion of patients with large baseline ischaemic cores undergoing endovascular therapy with the outcomes of matched controls...

The Society of Vascular and Interventional Neurology (SVIN) has announced the launch of Mission Thrombectomy 2020, an initiative to enhance global efforts to improve...

The US Food and Drug Administration (FDA) has cleared an expanded indication for the Solitaire stent retriever device (Medtronic). The FDA now allows the...

Neuravi has announced €15 million in venture debt financing from IPF Partners, a leading alternative financing provider focused on the healthcare sector. This financing allows...

A new study comparing acute damage to the arterial wall caused by ADAPT (a direct aspiration first pass technique) or stent retrievers during thrombectomy...

Now that mechanical thrombectomy for the treatment of acute ischaemic stroke is on its way to becoming well-established practice, new devices are beginning to...

While the proven success and corresponding uptake of mechanical thrombectomy for the treatment of acute ischaemic stroke has undoubtedly changed the face of stroke...

There is no doubt now that mechanical thrombectomy has been established as the new standard of care for the treatment of emergent large vessel...

In an analysis that included nearly 1,300 patients with large-vessel ischaemic stroke, earlier treatment with endovascular thrombectomy (intra-arterial use of a micro-catheter or other...

The treatment of mechanical thrombectomy represents a highly effective therapy in patients with acute ischaemic stroke. This was recently proven by four randomised controlled...

In recent years the neurointerventional field has seen many changes, especially in the area of stroke treatment. It is now becoming increasingly important how...

Women and minorities may be less likely to receive treatment for stroke, according to a study published in a recent online issue of Neurology,...

Neuravi has received CE mark approval for newly available enhancements to its EmboTrap stent retriever platform, the EmboTrap II revascularisation device. The company will...

The US Food and Drug Administration (FDA) has allowed marketing of two Trevo (Stryker Neurovascular) clot retrieval devices as an initial therapy for ischaemic...

The Penumbra 3D trial of the company’s 3D revascularisation device has successfully met the primary trial endpoints, demonstrating non-inferiority in both safety and efficacy...

Penumbra has launched its new ACE 68 reperfusion catheter in the USA.  The catheter is part of the Penumbra System, and was launched at...

A study of the long-term use of the ADAPT technique for the treatment of acute ischaemic stroke has confirmed that it is an efficient...

It has now been universally accepted that mechincal thrombectomy for the treatment of patients with acute ischaemic stroke with large vessel occlusions is the...

  The World Stroke Organization has announced a global partnership with Medtronic to increase stroke awareness through several initiatives. The two organisations will work together with...

Acute ischaemic stroke is the second most common cause of death and disability in Europe. The evidence in the recently published or presented randomised...

Data from the first 500 patients enrolled in the Trevo Registry were presented at the European Stroke Organisation Conference (ESOC; 10-12 May, Barcelona, Spain)...

Amnis Therapeutics has announced successful results in its pre-clinical trials, which tested the safety and efficacy of the Golden Retriever neuro thrombectomy device. The...

The phenox pREset and pREset LITE thrombectomy devices have been included in the study portfolio of the SITS Open clinical trial. Two other devices...

Siemens’ unique technology optimally supports a one-stop-shop workflow. After clinical NIHSS-based pre-selection, the imaging technologies provided by Siemens help to detect rare cases of...

By Aquilla Turk In the last year, five prospective randomised clinical trials have demonstrated the superiority of endovascular thrombectomy over medical management for the treatment...

Stent retriever technology has been named by the Cleveland Clinic as a top medical innovation. It was part of a list of the top...

While the traditional unsheathing technique for the deployment of stent retrievers has proved successful in clinical use, in their experience, Raul Gomes Nogueira (Emory...

Medtronic plc has announced that it has acquired Lazarus Effect, a Campbell, California, USA-based and privately-held medical device company focused on acute ischaemic stroke...

Medtronic plc has announced the US launch of the Arc support catheter, the most navigable, 6F tapered support catheter available. Developed to improve delivery of...

Penumbra has announced that the results of the European multicentre study of the company’s ACE64 thrombectomy system were presented in the Abstract Presentations Session at...

Penumbra has announced that the company’s ACE64 aspiration thrombectomy system received 510(k) marketing clearance from the US Food and Drug Administration for the revascularisation...

Diogo Haussen and colleagues (Emory University School of Medicine, Atlanta, USA) report that their initial data suggest that treatment of distal cerebrovascular occlusions with...

With the publication of two more stroke trials, the evidence in favour of endovascular treatment in patients with acute ischaemic stroke has reached new heights. Data from SWIFT PRIME and REVASCAT add to that of three other trials-MR CLEAN, EXTEND-IA and ESCAPE-that have begun to change the face of ischaemic stroke treatment.

Two new clinical trials on the treatment of stroke (ESCAPE and EXTEND IA) demonstrate that neurointerventional surgery significantly increases the number of patients who are able to live independently without major neurological disabilities.

Stryker has launched the Trevo XP ProVue retrieval system, a second generation fully visible stent retriever to treat acute ischaemic stroke.