Cascade17 dynamic non-occlusive remodelling net launched to European market 

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Perflow Medical has launched its Cascade17 non-occlusive remodelling net to the European market. According to a company press release the device has already received its first clinical use. 

The Cascade17 optimises non-occlusive support of distal and tortuous vessel anatomy during coil embolisation of intracranial aneurysms of smaller vessels, according to Perflow. The Cascade17 is the latest addition to the company’s portfolio of neurovascular devices based on a novel proprietary technology platform, the CEREBRAL NET, which includes the Stream Dynamic Neuro-Thrombectomy Net (Stream Net).

The company reports that early clinical experience with the Cascade17 is promising and further expands the range of brain vessels that can now be treated with Perflow’s CEREBRAL NET technology. Perflow claim the non-occlusive net design enables continuous blood flow during cerebral aneurysm repair and coiling, which maintains appropriate perfusion and may improve patient outcomes.

“The ability to perform Cascade-supported aneurysm coiling without the need to use an occlusive balloon or to place a stent in patients with brain aneurysms provides clinicians with a unique opportunity to safely position embolic coils in challenging situations and deliver a successful treatment without putting patients on lifelong medication,” said Xavier Barreau, Senior Interventional Neuroradiologist at CHU de Bordeaux, Bordeax, France, who was the first physician to use the Cascade17 clinically. “After a series of successful treatments with the Cascade Agile, we recently began using the Cascade17 to treat aneurysms in smaller vessels where access through a thinner microcatheter is preferred. The Cascade17 could easily be navigated to the distal anatomy, and the radiopaque braid structure provided excellent coil support. We look forward to continue using this unique device in our routine practice.”

“We are excited to start 2021 with the launch of the Cascade17,” commented Danny Farin, CEO of Perflow Medical. “This important milestone builds on the success of the Cascade product family and is the first of several exciting product announcements to come, including Stream17 Dynamic Neuro-Thrombectomy Net, as well as other new products for different indications we are currently working on.”

The Cascade Net and Stream Net product families are commercially available across Europe for the treatment of intracranial aneurysms and acute ischemic stroke, respectively. Perflow products are not yet approved for clinical use within the United States.


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