Meta-analysis of acute migraine treatment devices finds evidence in support of the REN method

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According to a press release produced by Theranica, a peer-reviewed study published in The Journal of Headache and Pain, has concluded that remote electrical neuromodulation (REN) was the only neuromodulation-based acute migraine treatment with sufficient clinical evidence to conclude that it is effective.

According to the press release, the study examined 38 peer-reviewed studies focusing on the effect of neuromodulation treatment on migraine patients.

Seven of the studies focused on acute treatment and the ability of different devices to deliver either pain relief or pain freedom at two hours. Secondary outcomes were assessed by improvement in quality of life, the need for rescue medication and the Patient Global Impression of Change Score.

Stephem Silbertein, director of the Headache Center at Jefferson University Hospital, Philadelphia, USA, commented, “As non-invasive neuromodulation is an emerging field in the treatment of migraine, an unbiased systemic review was important to understand what may really be benefitting patients.” He continued, “While the industry should conduct more studies to understand the potential of neuromodulation for migraine treatment, this study certainly helps comparing between the different emerging techniques.”


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