MATERNA-X study reveals benefits of radiation shielding during pregnancy

Matthew Zidan presenting at ESMINT 2026

“Protecting the foetus begins with protecting the mother,” was the concluding message delivered by Matthew Zidan (Bonn University Hospital, Bonn, Germany) based on late-breaking findings from the MATERNA-X study presented at the 2026 European Society of Minimally Invasive Neurological Therapy (ESMINT) congress (2–4 September, Marseille, France).

The study used a ‘fake’ pregnant woman’s belly filled with different amounts of water to simulate amniotic fluid in order to compare theoretical radiation dosage to a foetus—with versus without the Nova-X system (Cathpax)—during the three trimesters of pregnancy.

Its results indicated radiation dosage reductions of 49%, 35% and 57% during the first, second and third trimesters, respectively. Zidan noted that the foetus therefore appears to benefit from their mother’s full-body protection, even during the period before the pregnancy is known about, which underscores the value of a shielding system that is used routinely as opposed to relying on individual adjustments over time.

Zidan went on to conclude that full-body shielding seems to be provided—regardless of abdominal circumference—during the later trimesters, with preliminary data indicating that the additional hourly dose to the foetus with Nova-X appeared to be comparable to environmental background radiation (0.1μSv) through each of the three trimesters.

“As a mother of two, I know very well the concerns women have when working in the angio suite during pregnancy,” commented Franziska Dorn (Bonn University Hospital, Bonn, Germany), congress chair for ESMINT 2026. “The MATERNA-X study addresses a topic that is highly relevant for our field: concerns about radiation during pregnancy remain a real barrier for women considering a career in neurointervention. Our key message is that a full-body shielding system can protect the unborn child from the very first weeks, often before a pregnancy has been disclosed. If we can bring foetal exposure close to background levels, we remove one of the reasons talented women leave or avoid our specialty.”


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