Tag: thrombolysis
Dual antiplatelet therapy comparable to thrombolysis in minor, non-disabling ischaemic stroke
Among Chinese patients with minor, non-disabling stroke presenting <4.5 hours from symptom onset, dual antiplatelet therapy (DAPT) has been found to be non-inferior to...
Prior thrombolysis improves outcomes for M2 occlusion stroke patients undergoing thrombectomy
Intravenous thrombolysis (IVT) prior to a mechanical thrombectomy procedure could result in better functional outcomes than thrombectomy alone in stroke patients with M2 occlusions,...
European Stroke Organisation taskforce delivers update on thrombolytic drug shortages
The thrombolysis taskforce of the European Stroke Organisation (ESO) executive committee has provided an update on current shortages of alteplase and tenecteplase, detailing outcomes...
World Stroke Congress bolsters evidence on optimal thrombectomy and thrombolysis approaches
While much-needed improvements to existing triage and transport protocols for acute stroke patients were a leading topic of focus on World Stroke Day (29...
US study bolsters recent evidence supporting tenecteplase in ischaemic stroke care
Tenecteplase, a newer-generation intravenous thrombolysis (IVT) drug, has outperformed the traditional treatment (alteplase) for ischaemic strokes in several key areas, demonstrating better health outcomes...
Study findings encourage direct EVT approaches over bridging thrombolysis in select...
A retrospective study involving more than 200 patients has indicated that ‘bridging thrombolysis’ may not be associated with improved functional outcomes in stroke patients...
Newer clot-busting medication may someday increase time window for stroke treatment
In a phase 2a clinical trial in China, the clot-busting medication tenecteplase has been shown to be effective in restoring blood flow to the...
Direct mechanical thrombectomy fails to show non-inferiority compared with IV t-PA...
The preliminary results of the SWIFT-DIRECT (Solitaire with the intention for thrombectomy plus IV t-PA versus direct Solitaire stent-retriever thrombectomy in acute anterior circulation...
Benefits of EVT for basilar artery occlusion “cannot be excluded” following...
A randomised controlled trial (RCT) involving 300 patients found that functional outcomes among basilar artery occlusion stroke patients “did not differ significantly” with endovascular...
Noninferiority of thrombectomy alone further demonstrated in acute ischaemic stroke treatment
The noninferiority of mechanical thrombectomy alone—compared to mechanical thrombectomy plus intravenous tissue plasminogen activator (IV-tPA)—for the treatment of acute ischaemic stroke has been demonstrated...
Case report indicates 3D black blood vessel wall imaging can predict...
The early findings from a case report have highlighted the potential held by 3D black blood vessel wall post-contrast imaging to predict the outcomes...
Thrombolysis versus thrombectomy: Honours even between basilar occlusion treatments in CX...
Thrombolysis is considered as effective as mechanical thrombectomy for the treatment of basilar artery occlusion (BAO)—despite existing evidence on both intervention options being limited....
ISC News: Non-inferiority for direct mechanical thrombectomy “could not be proven”
Skipping IV thrombolysis and using mechanical clot removal alone for stroke was not shown to be non-inferior compared to the combination of both treatments,...
MR CLEAN II trials are expanding into France
The recent European Society of Minimally Invasive Neurological Therapy (ESMINT; 4–6 September, Nice, France) meeting saw Adriaan C G M van Es of Erasmus...
The blood pressure paradox in acute ischaemic stroke “lies in the...
The relationship between blood pressure and outcomes is highly dependent on reperfusion, conclude Lang Hong (Fudan University, Shanghai, China) and colleagues on behalf of...
Intensive blood pressure lowering beyond recommendations safely reduced the risk of...
Although intensive blood pressure lowering with intravenous thrombolysis is safe in patients with acute ischaemic stroke, the observed reduction in intracranial haemorrhage did not...
Debate: IV thrombolysis in acute stroke treatment is dead
It has now been universally accepted that mechincal thrombectomy for the treatment of patients with acute ischaemic stroke with large vessel occlusions is the...
