First clinical use of the Cascade Dynamic non-occlusive remodeling net announced


Perflow Medical has announced the first clinical cases of the Cascade Dynamic Non-Occlusive Remodeling Net earlier this month by Alejandro Tomasselo at Hospital Vall d’Hebron in Barcelona, Spain.

The Cascade Net is the latest addition to the Perflow’s portfolio of novel neurovascular devices based on the patent-protected CEREBRAL NET Technology platform. To support their continued commercial expansion, Perflow Medical also announces the acquisition of Israeli medtech developer and manufacturer TailorMed.

The Cascade device is a non-occlusive net that provides mechanical support during coil embolisation of intracranial aneurysms. Designed to improve procedural efficiency for the coiling of aneurysms, the device provides temporary support, through its compliant net while allowing continuous blood flow in the parent vessel. The unique cell design and braiding technology have superior flow permeability, an advantage over current techniques that require full occlusion of the vessel during the procedure. The braided net’s cell size is optimised to avoid coil entanglement during deployment, while the configuration enables superior compliance to the vessel anatomy and ease of deployment in bifurcations and other challenging vessel anatomies.

“My clinical experience with the Cascade Net has been very positive. It improved control during the coiling procedure and the braided net design significantly expanded my treatment options,” commented Tomasselo, Head of Interventional Neuroradiology at Hospital Vall d’Hebron, Barcelona, Spain. “It can help prevent the coils from herniating into the parent vessel, compact the coils during the procedure, and manipulate the coiling microcatheter, if needed, all while blood flows freely through the net. I look forward to incorporating the device as part of my clinical practice.


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