Tag: alteplase

EXTEND-IA TNK Part 2 trial finds no benefit of higher tenecteplase...

With the original trial demonstrating a higher incidence of substantial reperfusion with tenecteplase compared with alteplase prior to endovascular therapy, EXTEND-IA TNK Part 2...
Alteplase

Alteplase at 0.6mg/kg for stroke with unknown time of onset is...

Although an acceptable safety profile was demonstrated for MRI-guided thrombolysis with alteplase at 0.6mg/kg for stroke with unknown time of onset, the latter approach...

Tenecteplase reduces the need for thrombectomy compared to alteplase

Results from the Tenecteplase Versus Alteplase Before Endovascular Therapy for Ischemic Stroke (EXTEND-IA TNK) study show that the use of tenecteplase (0.25mg/kg) led to...