Initial results of the EXPEDITE clinical study have shown Neural Analytics’ Transcranial Doppler technology platform , to be more than 95% accurate for the early detection of acute ischaemic stroke (AIS) due to large vessel occlusion (LVO). The data were presented at the 26th annual European Stroke Conference, taking place from 24–26 May in Berlin, Germany.
“Current standard of care for stroke diagnosis can be expensive and time consuming, underscoring a significant unmet need for an improved method for first responders and emergency room physicians to rapidly and accurately assess and triage patients for appropriate clinical intervention,” says Thomas Devlin, principal study investigator and medical director of Erlanger Health System’s Southeast Regional Stroke Center in Chattanooga, USA.
The EXPEDITE study, conducted at Erlanger Health System, examined the effectiveness of Neural Analytics’ transcranial Doppler (TCD) platform in assessing patients for stroke.
The research study evaluated 45 subjects either experiencing computed tomography angiography (CTA) confirmed AIS due to LVO of the internal carotid artery (ICA) or middle cerebral artery (MCA) or matched healthy controls. TCD scans were recorded in 30 second intervals across multiple depths for each brain hemisphere while patients awaited treatment. Data were analysed using two different stroke assessment algorithms. A stroke asymmetry index (SAI) which compared depth matched bilateral scans and a stroke waveform morphology index (SMI) which used an algorithm to asses Doppler waveform morphology changes. Both methods were 96% accurate for assessing large vessel occlusion.