A device described as the latest addition to a growing group of ‘super-large bore’ catheter technologies has demonstrated “extremely positive” outcomes in early clinical usage.
At the recent BRAIN conference (2–4 December 2024, London, UK), Shahram Majidi (Department of Neurosurgery, Mount Sinai Health System, New York City, USA) presented his experiences with Cereglide 92 (Johnson & Johnson MedTech Neurovascular), relaying that the novel 0.092-inch catheter may enable higher first-pass effect rates as well as faster procedure times.
Majidi’s presentation included examples of three mechanical thrombectomy cases in which Cereglide 92 was used to treat large vessel occlusion (LVO) stroke patients via a direct aspiration technique. He noted during his talk that these cases—all of which ultimately saw a positive result—represent the first in-human treatments involving Cereglide 92 ever to be showcased at a medical conference.
Key characteristics of the device that Majidi highlighted include its enhanced trackability, the level of support it provides, and its atraumatic tip—all of which can help operators to capitalise on the benefits of flow modification and increased aspiration force brought about by these types of super-bore catheters. Usage of the Innerglide (Johnson & Johnson MedTech Neurovascular) delivery catheter, which is compatible with a 0.024-inch microwire, represents another feature of the system that—in Majidi’s view—further maximises the performance of Cereglide 92 in terms of reaching the M1 segment.
Providing a novel nugget of advice for those in the audience, the speaker also relayed that higher intracranial positioning of the guide catheter has been shown to lead to a faster recanalisation time when utilising large bore catheters like Cereglide 92 in stroke interventions, citing a recent publication and his own experiences.
Majidi went on to posit that, “in the era of expanding thrombectomy”, whereby his centre and many others are now performing multiple endovascular stroke procedures per day, efficiency and simplicity—including a straightforward setup, easy utilisation and compatibility of devices—are of paramount importance.
